Faculty evaluate, diagnose and treat endocrine and reproductive disorders including abnormal menses, amenorrhea, infertility, recurrent early pregnancy loss, ovulatory problems, uterine or tubal abnormalities.
Therapies may include hormonal and/or surgical treatment or advanced technologies such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).
The division provides an important educational setting for experiences provided to residents in obstetrics and gynecology, fellows in reproductive endocrinology and infertility, medical students and other learners.
RELATED FACULTY
Victor Shola Akinsooto
MBBS, FCOG, FRCSC
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Victor Shola Akinsooto is a Royal College of Physician and Surgeons of Canada certified reproductive endocrinologist and fertility specialist. He started his medical education at the University of Ilorin where he obtained his bachelor of medicine and surgery. After his residency at the University of Natal, he was admitted as a fellow of the South African College of Obstetricians and Gynaecologists. Following his Royal College of Physicians and Surgeons of Canada certification, in obstetrics and gynecology, he had a two year sub-specialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University. He is now an associate staff of Hamilton Health Sciences and an assistant clinical professor in the Department of Obstetrics & Gynecology, division of reproductive endocrinology and infertility at McMaster University.
Victor Shola Akinsooto
MBBS, FCOG, FRCSC
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
Shilpa Amin
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
ONE Fertility is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges. Visit the ONE Fertility Clinic website or call 1-877-663-0223 for more information.
RESEARCH INTERESTS
Infertility, polycystic ovary syndrome (PCOS), insulin resistance, Gonadatropins
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Shilpa Amin
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
Rolando Cepeda
MD
Associate Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Rolando Cepeda is an associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University. After completing medical school in Mexico, he entered a residency in obstetrics and gynecology at McMaster University, in 1989.
RESEARCH INTERESTS
- Education in bioethics – teaching and education research
- International Women’s Health – teaching and consultation (Uganda, Zambia, Zimbabwe, Pakistan, Ethiopia, Yemen)
Rolando Cepeda
MD
Associate Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
Stacy Deniz
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Stacy Deniz is a specialist in reproductive endocrinology and infertility. She obtained her specialty training in obstetrics and gynecology at McMaster University in 2012. She completed her two-year subspecialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University and joined the team at ONE Fertility. Dr. Deniz is a fellow of the Royal College of Physicians and Surgeons of Canada and an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University.
Her practice involves the management of patients with female and male factor infertility, polycystic ovarian syndrome, recurrent pregnancy loss, premature ovarian failure and endocrinologic disorders affecting the female reproductive system. Her research interests include the disposition of unused embryos following and in vitro fertilization (IVF) treatment cycle, as well as evaluating and improving the emotional support available to patients’ struggling with fertility issues. Dr. Deniz has advanced training in reproductive surgery including operative laparoscopy and hysteroscopy for fertility management. Most importantly, she is passionate about supporting couples and individuals along their fertility journey while helping them achieve their goal of parenthood.
RESEARCH INTERESTS
Embryo disposition; Mental health and fertility; Patient education and Information delivery; Psychosocial support through fertility treatments
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Ray, J. G., Deniz, S., Olivieri, A., Pollex, E., Vermeulen, M. J., Alexander, K. S.,… & Hamielec, C. M. (2003). Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel. BMC cardiovascular disorders, 3(1), 3.
Stacy Deniz
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
Mehrnoosh Faghih
MD, FRCSC, GREI
Associate Clinical Professor (Part-Time), GREI Fellowship Program Director
Reproductive Endocrinology & Infertility
BIO
Dr. Faghih completed medical school in Iran at Isfahan University of Medical Sciences, graduating at the top of her class. After moving to Canada, she pursued her residency in obstetrics and gynecology. She completed a two-year residency in gynecologic reproductive endocrinology and infertility at McMaster University, graduating in March of 2010. Dr. Faghih has been involved in teaching since 2007 as an instructor for the obstetrics and gynecology residency and clerkship programs at McMaster University. She was also extensively involved in the process of starting an accredited reproductive endocrinology and infertility fellowship program at McMaster. ONE Fertility Clinic is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges.
PUBLICATIONS
2016. Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
2016. Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
2013. Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
2011. Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
2008. Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Mehrnoosh Faghih
MD, FRCSC, GREI
Associate Clinical Professor (Part-Time), GREI Fellowship Program Director
Reproductive Endocrinology & Infertility
Edward Hughes
Professor Emeritus
Reproductive Endocrinology & Infertility
BIO
Edward G. Hughes is a professor of obstetrics and gynecology at McMaster University in Hamilton, Ontario, Canada. He is immediate past president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of fertility care.
After receiving an MBChB from the University of Liverpool Medical School, England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. He completed four years of post-fellowship training in reproductive endocrinology and infertility at the University of Ottawa and Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed his masters in clinical epidemiology and biostatistics.
In addition to training as a reproductive endocrine and Infertility specialist, Dr. Hughes has worked as a general practitioner in a remote area of Northern British Columbia, called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.
Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction and the inhibin/TGFß peptide family. He has recently led and completed a multi-centre randomized controlled trial of expectant management versus in vitro fertilization (EMVI). He is currently beginning research work on Art Therapy as a healing tool for women dealing with infertility. Dr. Hughes has lectured on these topics both nationally and internationally.
Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction and Canadian Medical Journal. He is an associate editor of the Journal Human Reproduction Update and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes also sits on the Science Advisory Panel to the Agency for Human Reproduction Canada.
PUBLICATIONS
O’Reilly, D., Bowen, J.M., Perampaladas, K., Qureshi, R., Xie, F. and Hughes, E., 2017. Feasibility of an altruistic sperm donation program in Canada: results from a population-based model. Reproductive Health, 14(1), p.8.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Hughes, E.G., Sawyer, A., DeJean, D. and Adamson, G.D., 2016. Cross-border reproductive care in North America: a pilot study testing a prospective data collection program for in vitro fertilization clinics in Canada and the United States. Fertility and sterility, 105(3), pp.786-790.
Beck, J.I., Boothroyd, C., Proctor, M., Farquhar, C. and Hughes, E., 2016. Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. Cochrane Database of Systematic Reviews, (1), pp.1-44.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Hughes, E.G., Grantmyre, J. and Zini, A., 2015. An Integrated Approach to Male-Factor Subfertility: Bridging the Gap Between Fertility Specialists Trained in Urology and Gynaecology. Journal of Obstetrics and Gynaecology Canada, 37(3), pp.258-265.
Hughes, E.G., 2015. Singleton birth at term: an old alarm or a new debate?. Human Reproduction, 30(10), pp.2254-2256.
Mohiyiddeen L, Hardiman A., Fitzgerald C., Hughes E., Mol BJ, Johnson N, Watson. (2015) A Tubal Flushing for Subfertility. Cochrane Library.
Hughes, E. and Pierson, R., 2014. Art and Medicine: Hand and Glove. Journal of Obstetrics and Gynaecology Canada, 36(12), p.1136.
Pierson, R. and Hughes, E., 2014. The Birth of Cupid. Journal of Obstetrics and Gynaecology Canada, 36(3), p.280.
Hughes, E. and Pierson, R., 2014. Pregnant woman. Journal of Obstetrics and Gynaecology Canada, 36(4), p.368.
Pierson, R. and Hughes, E., 2014. Placenta Bowl. Journal of Obstetrics and Gynaecology Canada, 36(10), p.944.
Hughes, E. and Pierson, R., 2014. Mother and Child: A Quiet Mystery. Journal of Obstetrics and Gynaecology Canada, 36(9), p.848.
Pierson, R. and Hughes, E., 2014. Moche Pot. Journal of Obstetrics and Gynaecology Canada, 36(7), p.656.
Pierson, R. and Hughes, E., 2014. Medieval Caesarean Section. Journal of Obstetrics and Gynaecology Canada, 36(11), p.1040.
Hughes, E. and Pierson, R., 2014. From Cradle to Grave. Journal of Obstetrics and Gynaecology Canada, 36(8), p.752.
Hughes, E., and Pierson, R., 2014. William Smellie and the macabre side of obstetrical science. Journal of Obstetrics and Gynaecology Canada, 36(6), p.560.
Pierson, R. and Hughes, E., 2014. A new year—an old hope. Journal of Obstetrics and Gynaecology Canada, 36(1), p.96.
Hughes, E. and Pierson, R., 2014. Love Conquers All. Journal of Obstetrics and Gynaecology Canada, 36(2), p.192.
Pierson, R. and Hughes, E., 2014. Primitive Passion. Journal of Obstetrics and Gynaecology Canada, 36(5), p.464.
Hughes, E. and Pierson, R., 2013. The Arnolfini Wedding: The World’s Most Famous Phantom Pregnancy. Journal of Obstetrics and Gynaecology Canada, 35(12), p.1152.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Hughes, E. and Pierson, R., 2013. The Birth of Asclepius: A Postmortem Caesarean Like No Other. Journal of Obstetrics and Gynaecology Canada, 35(8), p.768.
Hughes, E. and Pierson, R., 2013. All Things Come From Eggs. Journal of Obstetrics and Gynaecology Canada, 35(1), p.96.
Hughes, E. and Pierson, R., 2013. The Animalcules of Antoni Van Leeuwenhoek. Journal of Obstetrics and Gynaecology Canada, 35(10), p.960.
van den Boogaard, N.M., Bensdorp, A.J., Rengerink, K.O., Barnhart, K., Bhattacharya, S., Custers, I.M., Coutifaris, C., Goverde, A.J., Guzick, D.S., Hughes, E.C. and Factor-Litvak, P., 2013. Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data. Human reproduction update, Jan- Feb;20(1):141-51.
Pierson, Roger, and FCAHS FEAS. “Motherhood Undone: A Magical Teaching Tool.” Journal of Obstetrics and Gynaecology Canada 35, no. 3 (2013): 288.
Hughes, E. and Pierson, R., 2013. Life on a half-shell. Journal of Obstetrics and Gynaecology Canada, 35(2), p.192.
Pierson, R. and Hughes, E., 2013. Imagine All the Species. Journal of Obstetrics and Gynaecology Canada, 35(11), p.1056.
Hughes, E. and Pierson, R., 2013. Frieze Frame. Journal of Obstetrics and Gynaecology Canada, 35(7), p.680.
Pierson, R. and Hughes E., 2013. Broken Dreams of Motherhood: Frida’s Pictures of Pain. J Obstet Gynaecol Can, 35(4), p.392.
Hughes, E., and Pierson R., 2013. Art and Reproductive Science: Celebrating a Glorious Marriage. J Obstet Gynaecol Can, 35(1), pp.17-18.
Hughes, E. and Pierson, R., 2013. A Dangerous Journey: Giving Birth in the 1800s. Journal of Obstetrics and Gynaecology Canada, 35(9), p.864.
Pierson, R. and Hughes, E., 2013. Love in Bloom. Journal of Obstetrics and Gynaecology Canada, 35(5), p.488.
Pierson, R. and Hughes, E., 2013. The Birth of Gossip. Journal of Obstetrics and Gynaecology Canada, 35(6), p.584.
Veltman-Verhulst, S.M., Cohlen, B.J., Hughes, E. and Heineman, M.J., 2012. Intra-uterine insemination for unexplained subfertility. Cochran Database Syst Rev. 2012 Sep 12;9
Sadeu, J.C., Doedée, A.M.C.M., Neal, M.S., Hughes, E.G. and Foster, W.G., 2012. Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses. Reproductive biomedicine online, 24(2), pp.174-179.
Shmorgun, D., Claman, P., Gysler, M., Hemmings, R., Cheung, A.P., Goodrow, G.J., Hughes, E.G., Min, J.K., Roberts, J., Senikas, V. and Wong, B.C.M., 2012. The diagnosis and management of ovarian hyperstimulation syndrome. International Journal of Gynecology & Obstetrics, 116(3), pp.268-273.
Hughes, E.G., van Wely, M. and Farquhar, C.M., 2012. Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication. Human Reproduction. 27 (1): 3-5.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Cook, J.L., Collins, J., Buckett, W., Racowsky, C., Hughes, E. and Jarvi, K., 2011. Assisted reproductive technology-related multiple births: Canada in an international context. Journal of Obstetrics and Gynaecology Canada, 33(2), pp.159-167.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.
Edward Hughes
Professor Emeritus
Reproductive Endocrinology & Infertility
Megan Karnis
MD, FRCSC
Associate Clinical Professor (Part-Time), Division Head (Reproductive Endocrinology & Infertility)
Reproductive Endocrinology & Infertility
BIO
Dr. Karnis is originally from Toronto. She pursued her undergraduate studies at McMaster University, where she earned a bachelor of arts and science. In 1993, she graduated from medical school at McMaster University. Dr. Karnis completed her internship at the University of Toronto, in the Department of Obstetrics and Gynecology. She then returned to McMaster for her residency in obstetrics and oynecology. Upon completion of her residency, Dr. Karnis moved to Boston, Massachusetts where she engaged in a three-year fellowship in reproductive endocrinology and infertility at Harvard Medical School, in conjunction with the Beth Israel Deaconess Medical Center and Boston IVF. Following her subspeciality training, she returned to Hamilton and joined the Hamilton Health Sciences Centre for Reproductive Care. In 2009, the Centre for Reproductive Care closed and she opened The Ontario Network of Experts in Fertility (ONE Fertility) with partners Dr. Shilpa Amin (GREI) and Mr. Mike Neal (Embryology). ONE Fertility is a full service fertility centre and reproductive endocrinology clinic. Dr. Karnis is a fellow of the Royal College of Physicians and Surgeons of Canada and is U.S. Board Eligible in obstetrics and gynecology and reproductive endocrinology and infertility.
RESEARCH INTERESTS
Research Themes
Infertility; Reproductive endocrinology; Turner syndrome
PUBLICATIONS
Tan, L., Krichevsky, L., Greenblatt, E., Casper, R., Laskin, C.A., Sierra, S., Hannam, T., Karnis, M.F., Librach, C.L. and Sharma, P.A., 2016. Retrospective analysis of the efficacy of ART and reproductive outcomes in females with Fragile X associated primary ovarian insufficiency. Fertility and Sterility, 106(3), p.e241.
Lin, A.E., Karnis, M.F., Calderwood, L., Crenshaw, M., Bhatt, A., Souter, I., Silberbach, M. and Reindollar, R.H., 2016. Proposal for a national registry to monitor women with Turner syndrome seeking assisted reproductive technology. Fertility and sterility, 105(6), pp.1446-1448.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Karnis, M., 2012. Fertility, pregnancy, and medical management of Turner syndrome in the reproductive years. Fertility and Sterility, 98(4), 787-791.
Karnis, M., 2012. Catastrophic Consequences of Assisted Reproduction: The Case of Turner Syndrome. Seminars in Reproductive Medicine, 30(02), 116-122.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Megan Karnis
MD, FRCSC
Associate Clinical Professor (Part-Time), Division Head (Reproductive Endocrinology & Infertility)
Reproductive Endocrinology & Infertility
Victor Shola Akinsooto
MBBS, FCOG, FRCSC
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Victor Shola Akinsooto is a Royal College of Physician and Surgeons of Canada certified reproductive endocrinologist and fertility specialist. He started his medical education at the University of Ilorin where he obtained his bachelor of medicine and surgery. After his residency at the University of Natal, he was admitted as a fellow of the South African College of Obstetricians and Gynaecologists. Following his Royal College of Physicians and Surgeons of Canada certification, in obstetrics and gynecology, he had a two year sub-specialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University. He is now an associate staff of Hamilton Health Sciences and an assistant clinical professor in the Department of Obstetrics & Gynecology, division of reproductive endocrinology and infertility at McMaster University.
Victor Shola Akinsooto
MBBS, FCOG, FRCSC
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Victor Shola Akinsooto is a Royal College of Physician and Surgeons of Canada certified reproductive endocrinologist and fertility specialist. He started his medical education at the University of Ilorin where he obtained his bachelor of medicine and surgery. After his residency at the University of Natal, he was admitted as a fellow of the South African College of Obstetricians and Gynaecologists. Following his Royal College of Physicians and Surgeons of Canada certification, in obstetrics and gynecology, he had a two year sub-specialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University. He is now an associate staff of Hamilton Health Sciences and an assistant clinical professor in the Department of Obstetrics & Gynecology, division of reproductive endocrinology and infertility at McMaster University.
Shilpa Amin
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
ONE Fertility is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges. Visit the ONE Fertility Clinic website or call 1-877-663-0223 for more information.
RESEARCH INTERESTS
Infertility, polycystic ovary syndrome (PCOS), insulin resistance, Gonadatropins
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Shilpa Amin
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
ONE Fertility is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges. Visit the ONE Fertility Clinic website or call 1-877-663-0223 for more information.
RESEARCH INTERESTS
Infertility, polycystic ovary syndrome (PCOS), insulin resistance, Gonadatropins
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Rolando Cepeda
MD
Associate Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Rolando Cepeda is an associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University. After completing medical school in Mexico, he entered a residency in obstetrics and gynecology at McMaster University, in 1989.
RESEARCH INTERESTS
- Education in bioethics – teaching and education research
- International Women’s Health – teaching and consultation (Uganda, Zambia, Zimbabwe, Pakistan, Ethiopia, Yemen)
Rolando Cepeda
MD
Associate Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Rolando Cepeda is an associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University. After completing medical school in Mexico, he entered a residency in obstetrics and gynecology at McMaster University, in 1989.
RESEARCH INTERESTS
- Education in bioethics – teaching and education research
- International Women’s Health – teaching and consultation (Uganda, Zambia, Zimbabwe, Pakistan, Ethiopia, Yemen)
Stacy Deniz
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Stacy Deniz is a specialist in reproductive endocrinology and infertility. She obtained her specialty training in obstetrics and gynecology at McMaster University in 2012. She completed her two-year subspecialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University and joined the team at ONE Fertility. Dr. Deniz is a fellow of the Royal College of Physicians and Surgeons of Canada and an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University.
Her practice involves the management of patients with female and male factor infertility, polycystic ovarian syndrome, recurrent pregnancy loss, premature ovarian failure and endocrinologic disorders affecting the female reproductive system. Her research interests include the disposition of unused embryos following and in vitro fertilization (IVF) treatment cycle, as well as evaluating and improving the emotional support available to patients’ struggling with fertility issues. Dr. Deniz has advanced training in reproductive surgery including operative laparoscopy and hysteroscopy for fertility management. Most importantly, she is passionate about supporting couples and individuals along their fertility journey while helping them achieve their goal of parenthood.
RESEARCH INTERESTS
Embryo disposition; Mental health and fertility; Patient education and Information delivery; Psychosocial support through fertility treatments
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Ray, J. G., Deniz, S., Olivieri, A., Pollex, E., Vermeulen, M. J., Alexander, K. S.,… & Hamielec, C. M. (2003). Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel. BMC cardiovascular disorders, 3(1), 3.
Stacy Deniz
MD
Assistant Clinical Professor (Part-Time)
Reproductive Endocrinology & Infertility
BIO
Dr. Stacy Deniz is a specialist in reproductive endocrinology and infertility. She obtained her specialty training in obstetrics and gynecology at McMaster University in 2012. She completed her two-year subspecialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University and joined the team at ONE Fertility. Dr. Deniz is a fellow of the Royal College of Physicians and Surgeons of Canada and an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University.
Her practice involves the management of patients with female and male factor infertility, polycystic ovarian syndrome, recurrent pregnancy loss, premature ovarian failure and endocrinologic disorders affecting the female reproductive system. Her research interests include the disposition of unused embryos following and in vitro fertilization (IVF) treatment cycle, as well as evaluating and improving the emotional support available to patients’ struggling with fertility issues. Dr. Deniz has advanced training in reproductive surgery including operative laparoscopy and hysteroscopy for fertility management. Most importantly, she is passionate about supporting couples and individuals along their fertility journey while helping them achieve their goal of parenthood.
RESEARCH INTERESTS
Embryo disposition; Mental health and fertility; Patient education and Information delivery; Psychosocial support through fertility treatments
PUBLICATIONS
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Ray, J. G., Deniz, S., Olivieri, A., Pollex, E., Vermeulen, M. J., Alexander, K. S.,… & Hamielec, C. M. (2003). Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel. BMC cardiovascular disorders, 3(1), 3.
Mehrnoosh Faghih
MD, FRCSC, GREI
Associate Clinical Professor (Part-Time), GREI Fellowship Program Director
Reproductive Endocrinology & Infertility
BIO
Dr. Faghih completed medical school in Iran at Isfahan University of Medical Sciences, graduating at the top of her class. After moving to Canada, she pursued her residency in obstetrics and gynecology. She completed a two-year residency in gynecologic reproductive endocrinology and infertility at McMaster University, graduating in March of 2010. Dr. Faghih has been involved in teaching since 2007 as an instructor for the obstetrics and gynecology residency and clerkship programs at McMaster University. She was also extensively involved in the process of starting an accredited reproductive endocrinology and infertility fellowship program at McMaster. ONE Fertility Clinic is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges.
PUBLICATIONS
2016. Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
2016. Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
2013. Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
2011. Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
2008. Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Mehrnoosh Faghih
MD, FRCSC, GREI
Associate Clinical Professor (Part-Time), GREI Fellowship Program Director
Reproductive Endocrinology & Infertility
BIO
Dr. Faghih completed medical school in Iran at Isfahan University of Medical Sciences, graduating at the top of her class. After moving to Canada, she pursued her residency in obstetrics and gynecology. She completed a two-year residency in gynecologic reproductive endocrinology and infertility at McMaster University, graduating in March of 2010. Dr. Faghih has been involved in teaching since 2007 as an instructor for the obstetrics and gynecology residency and clerkship programs at McMaster University. She was also extensively involved in the process of starting an accredited reproductive endocrinology and infertility fellowship program at McMaster. ONE Fertility Clinic is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges.
PUBLICATIONS
2016. Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
2016. Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
2013. Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
2011. Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
2008. Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Edward Hughes
Professor Emeritus
Reproductive Endocrinology & Infertility
BIO
Edward G. Hughes is a professor of obstetrics and gynecology at McMaster University in Hamilton, Ontario, Canada. He is immediate past president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of fertility care.
After receiving an MBChB from the University of Liverpool Medical School, England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. He completed four years of post-fellowship training in reproductive endocrinology and infertility at the University of Ottawa and Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed his masters in clinical epidemiology and biostatistics.
In addition to training as a reproductive endocrine and Infertility specialist, Dr. Hughes has worked as a general practitioner in a remote area of Northern British Columbia, called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.
Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction and the inhibin/TGFß peptide family. He has recently led and completed a multi-centre randomized controlled trial of expectant management versus in vitro fertilization (EMVI). He is currently beginning research work on Art Therapy as a healing tool for women dealing with infertility. Dr. Hughes has lectured on these topics both nationally and internationally.
Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction and Canadian Medical Journal. He is an associate editor of the Journal Human Reproduction Update and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes also sits on the Science Advisory Panel to the Agency for Human Reproduction Canada.
PUBLICATIONS
O’Reilly, D., Bowen, J.M., Perampaladas, K., Qureshi, R., Xie, F. and Hughes, E., 2017. Feasibility of an altruistic sperm donation program in Canada: results from a population-based model. Reproductive Health, 14(1), p.8.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Hughes, E.G., Sawyer, A., DeJean, D. and Adamson, G.D., 2016. Cross-border reproductive care in North America: a pilot study testing a prospective data collection program for in vitro fertilization clinics in Canada and the United States. Fertility and sterility, 105(3), pp.786-790.
Beck, J.I., Boothroyd, C., Proctor, M., Farquhar, C. and Hughes, E., 2016. Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. Cochrane Database of Systematic Reviews, (1), pp.1-44.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Hughes, E.G., Grantmyre, J. and Zini, A., 2015. An Integrated Approach to Male-Factor Subfertility: Bridging the Gap Between Fertility Specialists Trained in Urology and Gynaecology. Journal of Obstetrics and Gynaecology Canada, 37(3), pp.258-265.
Hughes, E.G., 2015. Singleton birth at term: an old alarm or a new debate?. Human Reproduction, 30(10), pp.2254-2256.
Mohiyiddeen L, Hardiman A., Fitzgerald C., Hughes E., Mol BJ, Johnson N, Watson. (2015) A Tubal Flushing for Subfertility. Cochrane Library.
Hughes, E. and Pierson, R., 2014. Art and Medicine: Hand and Glove. Journal of Obstetrics and Gynaecology Canada, 36(12), p.1136.
Pierson, R. and Hughes, E., 2014. The Birth of Cupid. Journal of Obstetrics and Gynaecology Canada, 36(3), p.280.
Hughes, E. and Pierson, R., 2014. Pregnant woman. Journal of Obstetrics and Gynaecology Canada, 36(4), p.368.
Pierson, R. and Hughes, E., 2014. Placenta Bowl. Journal of Obstetrics and Gynaecology Canada, 36(10), p.944.
Hughes, E. and Pierson, R., 2014. Mother and Child: A Quiet Mystery. Journal of Obstetrics and Gynaecology Canada, 36(9), p.848.
Pierson, R. and Hughes, E., 2014. Moche Pot. Journal of Obstetrics and Gynaecology Canada, 36(7), p.656.
Pierson, R. and Hughes, E., 2014. Medieval Caesarean Section. Journal of Obstetrics and Gynaecology Canada, 36(11), p.1040.
Hughes, E. and Pierson, R., 2014. From Cradle to Grave. Journal of Obstetrics and Gynaecology Canada, 36(8), p.752.
Hughes, E., and Pierson, R., 2014. William Smellie and the macabre side of obstetrical science. Journal of Obstetrics and Gynaecology Canada, 36(6), p.560.
Pierson, R. and Hughes, E., 2014. A new year—an old hope. Journal of Obstetrics and Gynaecology Canada, 36(1), p.96.
Hughes, E. and Pierson, R., 2014. Love Conquers All. Journal of Obstetrics and Gynaecology Canada, 36(2), p.192.
Pierson, R. and Hughes, E., 2014. Primitive Passion. Journal of Obstetrics and Gynaecology Canada, 36(5), p.464.
Hughes, E. and Pierson, R., 2013. The Arnolfini Wedding: The World’s Most Famous Phantom Pregnancy. Journal of Obstetrics and Gynaecology Canada, 35(12), p.1152.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Hughes, E. and Pierson, R., 2013. The Birth of Asclepius: A Postmortem Caesarean Like No Other. Journal of Obstetrics and Gynaecology Canada, 35(8), p.768.
Hughes, E. and Pierson, R., 2013. All Things Come From Eggs. Journal of Obstetrics and Gynaecology Canada, 35(1), p.96.
Hughes, E. and Pierson, R., 2013. The Animalcules of Antoni Van Leeuwenhoek. Journal of Obstetrics and Gynaecology Canada, 35(10), p.960.
van den Boogaard, N.M., Bensdorp, A.J., Rengerink, K.O., Barnhart, K., Bhattacharya, S., Custers, I.M., Coutifaris, C., Goverde, A.J., Guzick, D.S., Hughes, E.C. and Factor-Litvak, P., 2013. Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data. Human reproduction update, Jan- Feb;20(1):141-51.
Pierson, Roger, and FCAHS FEAS. “Motherhood Undone: A Magical Teaching Tool.” Journal of Obstetrics and Gynaecology Canada 35, no. 3 (2013): 288.
Hughes, E. and Pierson, R., 2013. Life on a half-shell. Journal of Obstetrics and Gynaecology Canada, 35(2), p.192.
Pierson, R. and Hughes, E., 2013. Imagine All the Species. Journal of Obstetrics and Gynaecology Canada, 35(11), p.1056.
Hughes, E. and Pierson, R., 2013. Frieze Frame. Journal of Obstetrics and Gynaecology Canada, 35(7), p.680.
Pierson, R. and Hughes E., 2013. Broken Dreams of Motherhood: Frida’s Pictures of Pain. J Obstet Gynaecol Can, 35(4), p.392.
Hughes, E., and Pierson R., 2013. Art and Reproductive Science: Celebrating a Glorious Marriage. J Obstet Gynaecol Can, 35(1), pp.17-18.
Hughes, E. and Pierson, R., 2013. A Dangerous Journey: Giving Birth in the 1800s. Journal of Obstetrics and Gynaecology Canada, 35(9), p.864.
Pierson, R. and Hughes, E., 2013. Love in Bloom. Journal of Obstetrics and Gynaecology Canada, 35(5), p.488.
Pierson, R. and Hughes, E., 2013. The Birth of Gossip. Journal of Obstetrics and Gynaecology Canada, 35(6), p.584.
Veltman-Verhulst, S.M., Cohlen, B.J., Hughes, E. and Heineman, M.J., 2012. Intra-uterine insemination for unexplained subfertility. Cochran Database Syst Rev. 2012 Sep 12;9
Sadeu, J.C., Doedée, A.M.C.M., Neal, M.S., Hughes, E.G. and Foster, W.G., 2012. Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses. Reproductive biomedicine online, 24(2), pp.174-179.
Shmorgun, D., Claman, P., Gysler, M., Hemmings, R., Cheung, A.P., Goodrow, G.J., Hughes, E.G., Min, J.K., Roberts, J., Senikas, V. and Wong, B.C.M., 2012. The diagnosis and management of ovarian hyperstimulation syndrome. International Journal of Gynecology & Obstetrics, 116(3), pp.268-273.
Hughes, E.G., van Wely, M. and Farquhar, C.M., 2012. Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication. Human Reproduction. 27 (1): 3-5.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Cook, J.L., Collins, J., Buckett, W., Racowsky, C., Hughes, E. and Jarvi, K., 2011. Assisted reproductive technology-related multiple births: Canada in an international context. Journal of Obstetrics and Gynaecology Canada, 33(2), pp.159-167.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.
Edward Hughes
Professor Emeritus
Reproductive Endocrinology & Infertility
BIO
Edward G. Hughes is a professor of obstetrics and gynecology at McMaster University in Hamilton, Ontario, Canada. He is immediate past president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of fertility care.
After receiving an MBChB from the University of Liverpool Medical School, England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. He completed four years of post-fellowship training in reproductive endocrinology and infertility at the University of Ottawa and Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed his masters in clinical epidemiology and biostatistics.
In addition to training as a reproductive endocrine and Infertility specialist, Dr. Hughes has worked as a general practitioner in a remote area of Northern British Columbia, called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.
Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction and the inhibin/TGFß peptide family. He has recently led and completed a multi-centre randomized controlled trial of expectant management versus in vitro fertilization (EMVI). He is currently beginning research work on Art Therapy as a healing tool for women dealing with infertility. Dr. Hughes has lectured on these topics both nationally and internationally.
Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction and Canadian Medical Journal. He is an associate editor of the Journal Human Reproduction Update and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes also sits on the Science Advisory Panel to the Agency for Human Reproduction Canada.
PUBLICATIONS
O’Reilly, D., Bowen, J.M., Perampaladas, K., Qureshi, R., Xie, F. and Hughes, E., 2017. Feasibility of an altruistic sperm donation program in Canada: results from a population-based model. Reproductive Health, 14(1), p.8.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Hughes, E.G., Sawyer, A., DeJean, D. and Adamson, G.D., 2016. Cross-border reproductive care in North America: a pilot study testing a prospective data collection program for in vitro fertilization clinics in Canada and the United States. Fertility and sterility, 105(3), pp.786-790.
Beck, J.I., Boothroyd, C., Proctor, M., Farquhar, C. and Hughes, E., 2016. Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. Cochrane Database of Systematic Reviews, (1), pp.1-44.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Hughes, E.G., Grantmyre, J. and Zini, A., 2015. An Integrated Approach to Male-Factor Subfertility: Bridging the Gap Between Fertility Specialists Trained in Urology and Gynaecology. Journal of Obstetrics and Gynaecology Canada, 37(3), pp.258-265.
Hughes, E.G., 2015. Singleton birth at term: an old alarm or a new debate?. Human Reproduction, 30(10), pp.2254-2256.
Mohiyiddeen L, Hardiman A., Fitzgerald C., Hughes E., Mol BJ, Johnson N, Watson. (2015) A Tubal Flushing for Subfertility. Cochrane Library.
Hughes, E. and Pierson, R., 2014. Art and Medicine: Hand and Glove. Journal of Obstetrics and Gynaecology Canada, 36(12), p.1136.
Pierson, R. and Hughes, E., 2014. The Birth of Cupid. Journal of Obstetrics and Gynaecology Canada, 36(3), p.280.
Hughes, E. and Pierson, R., 2014. Pregnant woman. Journal of Obstetrics and Gynaecology Canada, 36(4), p.368.
Pierson, R. and Hughes, E., 2014. Placenta Bowl. Journal of Obstetrics and Gynaecology Canada, 36(10), p.944.
Hughes, E. and Pierson, R., 2014. Mother and Child: A Quiet Mystery. Journal of Obstetrics and Gynaecology Canada, 36(9), p.848.
Pierson, R. and Hughes, E., 2014. Moche Pot. Journal of Obstetrics and Gynaecology Canada, 36(7), p.656.
Pierson, R. and Hughes, E., 2014. Medieval Caesarean Section. Journal of Obstetrics and Gynaecology Canada, 36(11), p.1040.
Hughes, E. and Pierson, R., 2014. From Cradle to Grave. Journal of Obstetrics and Gynaecology Canada, 36(8), p.752.
Hughes, E., and Pierson, R., 2014. William Smellie and the macabre side of obstetrical science. Journal of Obstetrics and Gynaecology Canada, 36(6), p.560.
Pierson, R. and Hughes, E., 2014. A new year—an old hope. Journal of Obstetrics and Gynaecology Canada, 36(1), p.96.
Hughes, E. and Pierson, R., 2014. Love Conquers All. Journal of Obstetrics and Gynaecology Canada, 36(2), p.192.
Pierson, R. and Hughes, E., 2014. Primitive Passion. Journal of Obstetrics and Gynaecology Canada, 36(5), p.464.
Hughes, E. and Pierson, R., 2013. The Arnolfini Wedding: The World’s Most Famous Phantom Pregnancy. Journal of Obstetrics and Gynaecology Canada, 35(12), p.1152.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Hughes, E. and Pierson, R., 2013. The Birth of Asclepius: A Postmortem Caesarean Like No Other. Journal of Obstetrics and Gynaecology Canada, 35(8), p.768.
Hughes, E. and Pierson, R., 2013. All Things Come From Eggs. Journal of Obstetrics and Gynaecology Canada, 35(1), p.96.
Hughes, E. and Pierson, R., 2013. The Animalcules of Antoni Van Leeuwenhoek. Journal of Obstetrics and Gynaecology Canada, 35(10), p.960.
van den Boogaard, N.M., Bensdorp, A.J., Rengerink, K.O., Barnhart, K., Bhattacharya, S., Custers, I.M., Coutifaris, C., Goverde, A.J., Guzick, D.S., Hughes, E.C. and Factor-Litvak, P., 2013. Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data. Human reproduction update, Jan- Feb;20(1):141-51.
Pierson, Roger, and FCAHS FEAS. “Motherhood Undone: A Magical Teaching Tool.” Journal of Obstetrics and Gynaecology Canada 35, no. 3 (2013): 288.
Hughes, E. and Pierson, R., 2013. Life on a half-shell. Journal of Obstetrics and Gynaecology Canada, 35(2), p.192.
Pierson, R. and Hughes, E., 2013. Imagine All the Species. Journal of Obstetrics and Gynaecology Canada, 35(11), p.1056.
Hughes, E. and Pierson, R., 2013. Frieze Frame. Journal of Obstetrics and Gynaecology Canada, 35(7), p.680.
Pierson, R. and Hughes E., 2013. Broken Dreams of Motherhood: Frida’s Pictures of Pain. J Obstet Gynaecol Can, 35(4), p.392.
Hughes, E., and Pierson R., 2013. Art and Reproductive Science: Celebrating a Glorious Marriage. J Obstet Gynaecol Can, 35(1), pp.17-18.
Hughes, E. and Pierson, R., 2013. A Dangerous Journey: Giving Birth in the 1800s. Journal of Obstetrics and Gynaecology Canada, 35(9), p.864.
Pierson, R. and Hughes, E., 2013. Love in Bloom. Journal of Obstetrics and Gynaecology Canada, 35(5), p.488.
Pierson, R. and Hughes, E., 2013. The Birth of Gossip. Journal of Obstetrics and Gynaecology Canada, 35(6), p.584.
Veltman-Verhulst, S.M., Cohlen, B.J., Hughes, E. and Heineman, M.J., 2012. Intra-uterine insemination for unexplained subfertility. Cochran Database Syst Rev. 2012 Sep 12;9
Sadeu, J.C., Doedée, A.M.C.M., Neal, M.S., Hughes, E.G. and Foster, W.G., 2012. Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses. Reproductive biomedicine online, 24(2), pp.174-179.
Shmorgun, D., Claman, P., Gysler, M., Hemmings, R., Cheung, A.P., Goodrow, G.J., Hughes, E.G., Min, J.K., Roberts, J., Senikas, V. and Wong, B.C.M., 2012. The diagnosis and management of ovarian hyperstimulation syndrome. International Journal of Gynecology & Obstetrics, 116(3), pp.268-273.
Hughes, E.G., van Wely, M. and Farquhar, C.M., 2012. Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication. Human Reproduction. 27 (1): 3-5.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Cook, J.L., Collins, J., Buckett, W., Racowsky, C., Hughes, E. and Jarvi, K., 2011. Assisted reproductive technology-related multiple births: Canada in an international context. Journal of Obstetrics and Gynaecology Canada, 33(2), pp.159-167.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.
Megan Karnis
MD, FRCSC
Associate Clinical Professor (Part-Time), Division Head (Reproductive Endocrinology & Infertility)
Reproductive Endocrinology & Infertility
BIO
Dr. Karnis is originally from Toronto. She pursued her undergraduate studies at McMaster University, where she earned a bachelor of arts and science. In 1993, she graduated from medical school at McMaster University. Dr. Karnis completed her internship at the University of Toronto, in the Department of Obstetrics and Gynecology. She then returned to McMaster for her residency in obstetrics and oynecology. Upon completion of her residency, Dr. Karnis moved to Boston, Massachusetts where she engaged in a three-year fellowship in reproductive endocrinology and infertility at Harvard Medical School, in conjunction with the Beth Israel Deaconess Medical Center and Boston IVF. Following her subspeciality training, she returned to Hamilton and joined the Hamilton Health Sciences Centre for Reproductive Care. In 2009, the Centre for Reproductive Care closed and she opened The Ontario Network of Experts in Fertility (ONE Fertility) with partners Dr. Shilpa Amin (GREI) and Mr. Mike Neal (Embryology). ONE Fertility is a full service fertility centre and reproductive endocrinology clinic. Dr. Karnis is a fellow of the Royal College of Physicians and Surgeons of Canada and is U.S. Board Eligible in obstetrics and gynecology and reproductive endocrinology and infertility.
RESEARCH INTERESTS
Research Themes
Infertility; Reproductive endocrinology; Turner syndrome
PUBLICATIONS
Tan, L., Krichevsky, L., Greenblatt, E., Casper, R., Laskin, C.A., Sierra, S., Hannam, T., Karnis, M.F., Librach, C.L. and Sharma, P.A., 2016. Retrospective analysis of the efficacy of ART and reproductive outcomes in females with Fragile X associated primary ovarian insufficiency. Fertility and Sterility, 106(3), p.e241.
Lin, A.E., Karnis, M.F., Calderwood, L., Crenshaw, M., Bhatt, A., Souter, I., Silberbach, M. and Reindollar, R.H., 2016. Proposal for a national registry to monitor women with Turner syndrome seeking assisted reproductive technology. Fertility and sterility, 105(6), pp.1446-1448.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Karnis, M., 2012. Fertility, pregnancy, and medical management of Turner syndrome in the reproductive years. Fertility and Sterility, 98(4), 787-791.
Karnis, M., 2012. Catastrophic Consequences of Assisted Reproduction: The Case of Turner Syndrome. Seminars in Reproductive Medicine, 30(02), 116-122.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.
Megan Karnis
MD, FRCSC
Associate Clinical Professor (Part-Time), Division Head (Reproductive Endocrinology & Infertility)
Reproductive Endocrinology & Infertility
BIO
Dr. Karnis is originally from Toronto. She pursued her undergraduate studies at McMaster University, where she earned a bachelor of arts and science. In 1993, she graduated from medical school at McMaster University. Dr. Karnis completed her internship at the University of Toronto, in the Department of Obstetrics and Gynecology. She then returned to McMaster for her residency in obstetrics and oynecology. Upon completion of her residency, Dr. Karnis moved to Boston, Massachusetts where she engaged in a three-year fellowship in reproductive endocrinology and infertility at Harvard Medical School, in conjunction with the Beth Israel Deaconess Medical Center and Boston IVF. Following her subspeciality training, she returned to Hamilton and joined the Hamilton Health Sciences Centre for Reproductive Care. In 2009, the Centre for Reproductive Care closed and she opened The Ontario Network of Experts in Fertility (ONE Fertility) with partners Dr. Shilpa Amin (GREI) and Mr. Mike Neal (Embryology). ONE Fertility is a full service fertility centre and reproductive endocrinology clinic. Dr. Karnis is a fellow of the Royal College of Physicians and Surgeons of Canada and is U.S. Board Eligible in obstetrics and gynecology and reproductive endocrinology and infertility.
RESEARCH INTERESTS
Research Themes
Infertility; Reproductive endocrinology; Turner syndrome
PUBLICATIONS
Tan, L., Krichevsky, L., Greenblatt, E., Casper, R., Laskin, C.A., Sierra, S., Hannam, T., Karnis, M.F., Librach, C.L. and Sharma, P.A., 2016. Retrospective analysis of the efficacy of ART and reproductive outcomes in females with Fragile X associated primary ovarian insufficiency. Fertility and Sterility, 106(3), p.e241.
Lin, A.E., Karnis, M.F., Calderwood, L., Crenshaw, M., Bhatt, A., Souter, I., Silberbach, M. and Reindollar, R.H., 2016. Proposal for a national registry to monitor women with Turner syndrome seeking assisted reproductive technology. Fertility and sterility, 105(6), pp.1446-1448.
Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.
Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.
Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.
Karnis, M., 2012. Fertility, pregnancy, and medical management of Turner syndrome in the reproductive years. Fertility and Sterility, 98(4), 787-791.
Karnis, M., 2012. Catastrophic Consequences of Assisted Reproduction: The Case of Turner Syndrome. Seminars in Reproductive Medicine, 30(02), 116-122.
Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.
Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.