BIO

Dr. Swati Agrawal is an expert in the field of Maternal and Fetal Medicine, renowned for her significant contributions to the management of complex fetal conditions and high-risk pregnancies. Her expertise is particularly pronounced in early anatomy fetal scanning and fetal neurosonography (brain scan for various brain anomalies), areas where she has demonstrated a steadfast commitment to the early detection and management of fetal developmental anomalies. She is an expert in prenatal diagnosis techniques and procedures like amniocentesis, chorionic villous sampling, amnioreduction and fetal cysts/ bladder aspiration.

In terms of educational background, Dr. Agrawal has successfully completed a Fellowship in Maternal and Fetal Medicine, earning sub-specialty board certification from The Royal College of Physicians and Surgeons of Canada. Subsequently, she did an additional year of training in placental complications in pregnancy and then another year solidifying skills in fetal neurosonogram. Additionally, she possesses a Master of Science in Clinical Embryology from the University of Oxford, UK, providing her with an intricate understanding of fetal development and the embryological components of prenatal healthcare.

Dr. Agrawal’s scholarly contributions include the publication of approximately 50 peer-reviewed articles in esteemed journals such as ‘Hypertension’, ‘BJOG’, and ‘AJOG’. Her work has been recognized with several prestigious awards, highlighting her research’s impact and relevance.

Outside of her professional achievements, Dr. Agrawal enjoys spending time with family and friends, hiking, practicing meditation, and reading, finding balance and inspiration in these activities.

CLINICAL INTERESTS

• Prenatal diagnosis (amniocentesis and CVS)
• Fetal procedures (amnioreduction, fetal cyst aspiration)
• Fetal ultrasound
• Fetal neurosonograms (fetal brain scan)
• Early anatomy ultrasound scans (12-16 weeks)
• Placental pathology (preeclampsia, fetal growth restriction)

BIO

Dr. Swati Agrawal is an expert in the field of Maternal and Fetal Medicine, renowned for her significant contributions to the management of complex fetal conditions and high-risk pregnancies. Her expertise is particularly pronounced in early anatomy fetal scanning and fetal neurosonography (brain scan for various brain anomalies), areas where she has demonstrated a steadfast commitment to the early detection and management of fetal developmental anomalies. She is an expert in prenatal diagnosis techniques and procedures like amniocentesis, chorionic villous sampling, amnioreduction and fetal cysts/ bladder aspiration.

In terms of educational background, Dr. Agrawal has successfully completed a Fellowship in Maternal and Fetal Medicine, earning sub-specialty board certification from The Royal College of Physicians and Surgeons of Canada. Subsequently, she did an additional year of training in placental complications in pregnancy and then another year solidifying skills in fetal neurosonogram. Additionally, she possesses a Master of Science in Clinical Embryology from the University of Oxford, UK, providing her with an intricate understanding of fetal development and the embryological components of prenatal healthcare.

Dr. Agrawal’s scholarly contributions include the publication of approximately 50 peer-reviewed articles in esteemed journals such as ‘Hypertension’, ‘BJOG’, and ‘AJOG’. Her work has been recognized with several prestigious awards, highlighting her research’s impact and relevance.

Outside of her professional achievements, Dr. Agrawal enjoys spending time with family and friends, hiking, practicing meditation, and reading, finding balance and inspiration in these activities.

CLINICAL INTERESTS

• Prenatal diagnosis (amniocentesis and CVS)
• Fetal procedures (amnioreduction, fetal cyst aspiration)
• Fetal ultrasound
• Fetal neurosonograms (fetal brain scan)
• Early anatomy ultrasound scans (12-16 weeks)
• Placental pathology (preeclampsia, fetal growth restriction)

BIO

Dr. Victor Shola Akinsooto is a Royal College of Physician and Surgeons of Canada certified reproductive endocrinologist and fertility specialist. He started his medical education at the University of Ilorin where he obtained his bachelor of medicine and surgery. After his residency at the University of Natal, he was admitted as a fellow of the South African College of Obstetricians and Gynaecologists. Following his Royal College of Physicians and Surgeons of Canada certification, in obstetrics and gynecology, he had a two year sub-specialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University. He is now an associate staff of Hamilton Health Sciences and an assistant clinical professor in the Department of Obstetrics & Gynecology, division of reproductive endocrinology and infertility at McMaster University.

BIO

Dr. Victor Shola Akinsooto is a Royal College of Physician and Surgeons of Canada certified reproductive endocrinologist and fertility specialist. He started his medical education at the University of Ilorin where he obtained his bachelor of medicine and surgery. After his residency at the University of Natal, he was admitted as a fellow of the South African College of Obstetricians and Gynaecologists. Following his Royal College of Physicians and Surgeons of Canada certification, in obstetrics and gynecology, he had a two year sub-specialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University. He is now an associate staff of Hamilton Health Sciences and an assistant clinical professor in the Department of Obstetrics & Gynecology, division of reproductive endocrinology and infertility at McMaster University.

BIO

ONE Fertility is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges. Visit the ONE Fertility Clinic website or call 1-877-663-0223 for more information.

RESEARCH INTERESTS

Infertility, polycystic ovary syndrome (PCOS), insulin resistance, Gonadatropins

PUBLICATIONS

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.

Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

BIO

ONE Fertility is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges. Visit the ONE Fertility Clinic website or call 1-877-663-0223 for more information.

RESEARCH INTERESTS

Infertility, polycystic ovary syndrome (PCOS), insulin resistance, Gonadatropins

PUBLICATIONS

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.

Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

Originally from Israel, Eran obtained his medical degree from Tel Aviv University and completed his residency training in obstetrics and gynecology at Lis Medical Center (affiliated with Tel Aviv University). At this tertiary care perinatal centre, with over 12,000 deliveries per annum, he developed his clinical interests in maternal fetal medicine and advanced his research skills by undertaking an advanced biostatistics program at Tel Aviv University.

Following an initial appointment as an assistant professor of obstetrics and gynecology at Tel Aviv University, Eran relocated to the University of Toronto, where he undertook subspecialty training in Canada’s largest maternal fetal medicine program, principally at Mount Sinai Hospital. His extended four-year period of training included one year of advanced obstetrics at St. Michael’s Hospital and a two-year period in Mount Sinai Hospital. In 2021, he obtained subspecialty certification in maternal fetal medicine from the Royal College of Physicians and Surgeons of Canada and completed his training with additional one year period within the Placenta Program at Mount Sinai Hospital.

Eran has continued to be a passionate team-based researcher. To date, he has authored and co-authored over 110 peer-reviewed original articles, reviews and book chapters, and has disseminated his work at many national and international level meetings.

In February 2022, Eran was appointed as an associate professor in the maternal fetal medicine division, Department of Obstetrics & Gynecology at McMaster University, Hamilton, Canada. His clinical and research interests focus on all aspects of prenatal diagnosis and management of both fetal and placenta disorders, with a focus on placental dysfunction and multifetal pregnancy. Eran has enjoyed working with a wide range of undergraduate and postgraduate learners and welcomes the opportunity to continue mentorship of next-generation academic physicians and scientists.

Originally from Israel, Eran obtained his medical degree from Tel Aviv University and completed his residency training in obstetrics and gynecology at Lis Medical Center (affiliated with Tel Aviv University). At this tertiary care perinatal centre, with over 12,000 deliveries per annum, he developed his clinical interests in maternal fetal medicine and advanced his research skills by undertaking an advanced biostatistics program at Tel Aviv University.

Following an initial appointment as an assistant professor of obstetrics and gynecology at Tel Aviv University, Eran relocated to the University of Toronto, where he undertook subspecialty training in Canada’s largest maternal fetal medicine program, principally at Mount Sinai Hospital. His extended four-year period of training included one year of advanced obstetrics at St. Michael’s Hospital and a two-year period in Mount Sinai Hospital. In 2021, he obtained subspecialty certification in maternal fetal medicine from the Royal College of Physicians and Surgeons of Canada and completed his training with additional one year period within the Placenta Program at Mount Sinai Hospital.

Eran has continued to be a passionate team-based researcher. To date, he has authored and co-authored over 110 peer-reviewed original articles, reviews and book chapters, and has disseminated his work at many national and international level meetings.

In February 2022, Eran was appointed as an associate professor in the maternal fetal medicine division, Department of Obstetrics & Gynecology at McMaster University, Hamilton, Canada. His clinical and research interests focus on all aspects of prenatal diagnosis and management of both fetal and placenta disorders, with a focus on placental dysfunction and multifetal pregnancy. Eran has enjoyed working with a wide range of undergraduate and postgraduate learners and welcomes the opportunity to continue mentorship of next-generation academic physicians and scientists.

BIO

Dr. Barrett is Professor and Chair of the Department of Obstetrics and Gynecology at McMaster University. He holds the F.L. Johnson Chair in Women’s Reproductive Health Research. Dr. Barrett received his training from the University of Witwatersrand in South Africa and the University of Newcastle Upon Tyne in the U.K and is well known for his work with preterm and multiple births as well as the care of their families.

Dr. Barrett is a World Health Organization advisor on Maternal Health and has just been appointed as Special Advisor on Maternal Mortality to the Government of Guyana.   He has been a Vice Chair of the Board of the Society of Obstetricians and Gynecologists and President of the Canadian Society of Maternal Fetal Medicine. He was the Founder and Chair of the Southern Ontario Obstetrical Network (SOON). Dr Barrett has recently been appointed by the Ontario Ministry of Health to Co-Chair the Regional Networks Operating Forum, a body formed to coordinate quality initiatives in the Ontario Maternal Child and Youth Networks.

He has held more than $25 million in grants, most prominently in the conduct of randomized controlled trials, wherein he has obtained international recognition in the field of multiple pregnancy.

BIO

Dr. Barrett is Professor and Chair of the Department of Obstetrics and Gynecology at McMaster University. He holds the F.L. Johnson Chair in Women’s Reproductive Health Research. Dr. Barrett received his training from the University of Witwatersrand in South Africa and the University of Newcastle Upon Tyne in the U.K and is well known for his work with preterm and multiple births as well as the care of their families.

Dr. Barrett is a World Health Organization advisor on Maternal Health and has just been appointed as Special Advisor on Maternal Mortality to the Government of Guyana.   He has been a Vice Chair of the Board of the Society of Obstetricians and Gynecologists and President of the Canadian Society of Maternal Fetal Medicine. He was the Founder and Chair of the Southern Ontario Obstetrical Network (SOON). Dr Barrett has recently been appointed by the Ontario Ministry of Health to Co-Chair the Regional Networks Operating Forum, a body formed to coordinate quality initiatives in the Ontario Maternal Child and Youth Networks.

He has held more than $25 million in grants, most prominently in the conduct of randomized controlled trials, wherein he has obtained international recognition in the field of multiple pregnancy.

BIO

Dr. Stephen Bates earned his medical degree from McMaster University in 1979 and entered a residency in family medicine. In 1984, he completed his residency in obstetrics and gynecology and began his general practice in obstetrics and gynecology, including colposcopy, laser surgery of the genital tract, hysteroscopy, endometrial ablation and operative laparoscopy. In 1994, he completed his MSc in clinical epidemiology and biostatistics at McMaster University.

In addition to his practice in Brantford, Dr. Bates has dedicated his career to education, working as a Clinical Professor in the Department of Obstetrics and Gynecology at McMaster University.

AWARDS

His teaching of health professionals at all levels has earned him numerous awards including the Association of Professors of Obstetrics and Gynecology (Canada) Educator of the Year Award in 2006, the Faculty of Health Sciences Undergraduate MD Program Outstanding Preceptor Award in 2007 and the 2008 CREOG National Faculty Award for Excellence in Resident Education.

RESEARCH INTERESTS

• Study design to assess non-hysterectomy surgical therapy for menorrhagia
• Quality Improvement in medical practice
• Teaching of health professional at all levels

PUBLICATIONS

Malinowski A, Bates SK. Semantics and Pitfalls in the Diagnosis of Cornual/Interstitial Pregnancy. Fertility and Sterility 2006; 86:1764. e11-4.

Bates SK. Postmenopausal Estrogen Replacement Therapy and Breast Cancer. Journal of the Society of Obstetricians & Gynecologists of Canada. September 1990; Volume 12, No. 7; page 9.

BIO

Dr. Stephen Bates earned his medical degree from McMaster University in 1979 and entered a residency in family medicine. In 1984, he completed his residency in obstetrics and gynecology and began his general practice in obstetrics and gynecology, including colposcopy, laser surgery of the genital tract, hysteroscopy, endometrial ablation and operative laparoscopy. In 1994, he completed his MSc in clinical epidemiology and biostatistics at McMaster University.

In addition to his practice in Brantford, Dr. Bates has dedicated his career to education, working as a Clinical Professor in the Department of Obstetrics and Gynecology at McMaster University.

AWARDS

His teaching of health professionals at all levels has earned him numerous awards including the Association of Professors of Obstetrics and Gynecology (Canada) Educator of the Year Award in 2006, the Faculty of Health Sciences Undergraduate MD Program Outstanding Preceptor Award in 2007 and the 2008 CREOG National Faculty Award for Excellence in Resident Education.

RESEARCH INTERESTS

• Study design to assess non-hysterectomy surgical therapy for menorrhagia
• Quality Improvement in medical practice
• Teaching of health professional at all levels

PUBLICATIONS

Malinowski A, Bates SK. Semantics and Pitfalls in the Diagnosis of Cornual/Interstitial Pregnancy. Fertility and Sterility 2006; 86:1764. e11-4.

Bates SK. Postmenopausal Estrogen Replacement Therapy and Breast Cancer. Journal of the Society of Obstetricians & Gynecologists of Canada. September 1990; Volume 12, No. 7; page 9.

BIO

Following the completion of her undergraduate medical degree at the University of Toronto, Dr. Best completed her residency training at McMaster University in 2009. She went on to do a two year fellowship in urogynecology and reconstructive pelvic surgery at the University of Toronto, Mount Sinai Hospital. Dr. Best returned to McMaster University and joined the Department of Obstetrics & Gynecology in 2012, with a clinical practice focused on pelvic organ prolapse and urinary incontinence, and a keen interest in surgical education.

In January 2016, Dr. Best moved her clinical practice to the community of Halton and began her work as a urogynecologist at the new Oakville Trafalgar Memorial Hospital. Surgical teaching has remained a priority in her daily practice, creating a new community site for the McMaster obstetrics and gynecology residents during the urogynecology rotation. Her practice is entirely dedicated to urogynecology, with an interest and focus on minimally invasive surgical techniques.

She is currently an assistant clinical professor in the Department of Obstetrics & Gynecology, McMaster University

AWARDS

• Academic Professionals in Obstetrics and Gynaecology (APOG) Carl Nimrod Educator Award 2015
• H.R. Morgan Surgical teaching Award 2015
• The American Association of Gynecologic Laparoscopists (AAGL) Resident Award for Excellence in Laparoscopy – 2009
• R. T. Weaver Resident Research Award – 2008

PUBLICATIONS

Lovatsis D, Best C, Diamond P. (2017). Short-term Uresta efficacy (SURE) study: a randomized controlled trial of the Uresta continence device. International Urogynecology Journal. January 2017 28(1). pp147

Leong Y, Kotani S, Best C, Diamond P, Lovatsis D, Drutz HP. (2017). A comparison of health-related quality of life of women awaiting pelvic organ prolapse surgery versus hip or knee replacement. JOGC May 2017, 39 (5)

Singh, S., Best, C., Dunn, S., Leyland, N. and Wolfman, W.L., 2016. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S231-S263.

Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Abnormal uterine bleeding in pre-menopausal women. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.47

Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., CLINIQUE-GYNECOLOGIE, C.D.P., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M. and Lemyre, M., 2013. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.476-479.

Best, C., Drutz, H.P. and Alarab, M., 2012. Obstetric anal sphincter injuries: a survey of clinical practice among Canadian obstetricians. Journal of Obstetrics and Gynaecology Canada, 34(8), pp.747-754.

Best, C., Drutz, H.P. and Alarab, M., 2012. Obstetric anal sphincter injuries: a survey of clinical practice among Canadian obstetricians. Journal of Obstetrics and Gynaecology Canada, 34(8), pp.747-754.

Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2011. Oral contraceptives and the risk of venous thromboembolism: an update. International Journal of Gynecology & Obstetrics, 112(3), pp.252-256.

Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Adhesion prevention in gynaecological surgery. International Journal of Gynecology & Obstetrics, 111(2), pp193-7.

Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Asymptomatic endometrial thickening. Journal of Obstetrics and Gynaecology Canada, 32(10), pp.990-999.

Leyland, N., Casper, R., Laberge, P., Singh, S.S., Allen, L., Arendas, K., Allaire, C., Awadalla, A., Best, C., Contestabile, E. and Dunn, S., 2010. Endometriosis: diagnosis and management. Journal of Obstetrics and Gynaecology Canada, 32(7), pp.S1-S3.

Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Épaississement endométrial asymptomatique. Journal of Obstetrics and Gynaecology Canada, 32(11), pp.1070-1081.

Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Hystérectomie supracervicale. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.69-76.

Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Prévention des adhérences en chirurgie gynécologique. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.603-608.

Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Supracervical hysterectomy. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.62-68.

McDonald, S., Best, C., Lam, K., 2010. P13 The recurrence risk of severe de novo preeclampsia in singleton pregnancies: a population-based cohort. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health, 1, p.S46.

Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2010. Oral contraceptives and the risk of venous thromboembolism: an update. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1192-1197.

BIO

Following the completion of her undergraduate medical degree at the University of Toronto, Dr. Best completed her residency training at McMaster University in 2009. She went on to do a two year fellowship in urogynecology and reconstructive pelvic surgery at the University of Toronto, Mount Sinai Hospital. Dr. Best returned to McMaster University and joined the Department of Obstetrics & Gynecology in 2012, with a clinical practice focused on pelvic organ prolapse and urinary incontinence, and a keen interest in surgical education.

In January 2016, Dr. Best moved her clinical practice to the community of Halton and began her work as a urogynecologist at the new Oakville Trafalgar Memorial Hospital. Surgical teaching has remained a priority in her daily practice, creating a new community site for the McMaster obstetrics and gynecology residents during the urogynecology rotation. Her practice is entirely dedicated to urogynecology, with an interest and focus on minimally invasive surgical techniques.

She is currently an assistant clinical professor in the Department of Obstetrics & Gynecology, McMaster University

AWARDS

• Academic Professionals in Obstetrics and Gynaecology (APOG) Carl Nimrod Educator Award 2015
• H.R. Morgan Surgical teaching Award 2015
• The American Association of Gynecologic Laparoscopists (AAGL) Resident Award for Excellence in Laparoscopy – 2009
• R. T. Weaver Resident Research Award – 2008

PUBLICATIONS

Lovatsis D, Best C, Diamond P. (2017). Short-term Uresta efficacy (SURE) study: a randomized controlled trial of the Uresta continence device. International Urogynecology Journal. January 2017 28(1). pp147

Leong Y, Kotani S, Best C, Diamond P, Lovatsis D, Drutz HP. (2017). A comparison of health-related quality of life of women awaiting pelvic organ prolapse surgery versus hip or knee replacement. JOGC May 2017, 39 (5)

Singh, S., Best, C., Dunn, S., Leyland, N. and Wolfman, W.L., 2016. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S231-S263.

Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Abnormal uterine bleeding in pre-menopausal women. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.47

Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., CLINIQUE-GYNECOLOGIE, C.D.P., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M. and Lemyre, M., 2013. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.476-479.

Best, C., Drutz, H.P. and Alarab, M., 2012. Obstetric anal sphincter injuries: a survey of clinical practice among Canadian obstetricians. Journal of Obstetrics and Gynaecology Canada, 34(8), pp.747-754.

Best, C., Drutz, H.P. and Alarab, M., 2012. Obstetric anal sphincter injuries: a survey of clinical practice among Canadian obstetricians. Journal of Obstetrics and Gynaecology Canada, 34(8), pp.747-754.

Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2011. Oral contraceptives and the risk of venous thromboembolism: an update. International Journal of Gynecology & Obstetrics, 112(3), pp.252-256.

Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Adhesion prevention in gynaecological surgery. International Journal of Gynecology & Obstetrics, 111(2), pp193-7.

Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Asymptomatic endometrial thickening. Journal of Obstetrics and Gynaecology Canada, 32(10), pp.990-999.

Leyland, N., Casper, R., Laberge, P., Singh, S.S., Allen, L., Arendas, K., Allaire, C., Awadalla, A., Best, C., Contestabile, E. and Dunn, S., 2010. Endometriosis: diagnosis and management. Journal of Obstetrics and Gynaecology Canada, 32(7), pp.S1-S3.

Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Épaississement endométrial asymptomatique. Journal of Obstetrics and Gynaecology Canada, 32(11), pp.1070-1081.

Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Hystérectomie supracervicale. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.69-76.

Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Prévention des adhérences en chirurgie gynécologique. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.603-608.

Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Supracervical hysterectomy. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.62-68.

McDonald, S., Best, C., Lam, K., 2010. P13 The recurrence risk of severe de novo preeclampsia in singleton pregnancies: a population-based cohort. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health, 1, p.S46.

Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2010. Oral contraceptives and the risk of venous thromboembolism: an update. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1192-1197.

BIO

Dr. Rolando Cepeda is an associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University. After completing medical school in Mexico, he entered a residency in obstetrics and gynecology at McMaster University, in 1989.

RESEARCH INTERESTS

• Education in bioethics – teaching and education research
• International Women’s Health – teaching and consultation (Uganda, Zambia, Zimbabwe, Pakistan, Ethiopia, Yemen)

BIO

Dr. Rolando Cepeda is an associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University. After completing medical school in Mexico, he entered a residency in obstetrics and gynecology at McMaster University, in 1989.

RESEARCH INTERESTS

• Education in bioethics – teaching and education research
• International Women’s Health – teaching and consultation (Uganda, Zambia, Zimbabwe, Pakistan, Ethiopia, Yemen)

BIO

After completing her BSc in biochemistry at the University of Toronto, Dr. Jean Chamberlain attended medical school at the University of Toronto. She earned her MD in 1991 and completed a rotating internship at Toronto East General Hospital in 1992. Upon completion of a Royal College Fellowship in obstetrics and gynecology at the University of Western Ontario in 1996, Dr. Chamberlain joined the Department of Obstetrics & Gynecology at McMaster University. She completed her master of education at the University of Toronto (OISE) in 1998.

Dr. Chamberlain is also co-director of the McMaster International Women’s Health Program and founding director of Save the Mothers (STM) International, an organization dedicated to saving some of the 287,000 mothers who die in childbirth every year. Dr. Chamberlain is an internationally recognized expert in women’s health and is a member of the Order of Canada. Her work has earned her several awards including the 2006 International Community Service Award from the Federation of International Obstetricians/Gynecologists for her outstanding contribution to the health of mothers around the world.

Dr. Chamberlain also received the Teasdale-Corti Humanitarian Award from the Royal College of Physicians and Surgeons of Canada in 2009.

She has spent 12 years working in Uganda advocating for safe motherhood with Save the Mothers. Before her tenure in Uganda, she spent five years in Yemen as an obstetrician/gynecologist. While abroad, she maintained her academic position in obstetrics and gynecology at McMaster University. Currently, she is a professor at McMaster University with her clinical practice based out of St Joseph’s Hospital Hamilton.

RESEARCH INTERESTS

International women’s health, public health leadership, advocacy, refugee and immigrant women

HONOURS & AWARDS

• International Community Service Award, Federation of International Obstetricians/Gynecologists (2006)
• Teasdale-Corti Humanitarian Award for work improving maternal health, Royal College of Physicians and Surgeons of Canada (2009)
• Prix d’Excellence for going beyond the call of duty, Royal College of Physicians and Surgeons of Canada (2012)
• Queen Elizabeth II Diamond Jubilee medal (2012)
• Iductee, Hamilton Gallery of Distinction (2013)
• Mission Legacy Award, The Sisters of St. Joseph, Hamilton (2013)
• Honorary Doctorate of Laws, University of Waterloo (2013)
• Member, Order of Canada (2014)

PUBLICATIONS

Jarde, A., Lutsiv, O., Park, C.K., Beyene, J., Dodd, J.M., Barrett, J., Shah, P.S., Cook, J.L., Saito, S., Biringer, A.B. and Sabatino, L., 2017. Effectiveness of progesterone, cerclage and pessary for preventing preterm birth in singleton pregnancies: a systematic review and network meta-analysis. BJOG: An International Journal of Obstetrics & Gynaecology.

Jarde, A., Lutsiv, O., Park, C., Gulmezoglu, M., Shah, P., Biringer, A., Saito, S., Cook, J., Vera, C., Barrett, J. and Chamberlain, J., 2016. Progesterone, cervical cerclage and cervical pessary for primary prevention of preterm birth in high risk singleton pregnancies: a systematic review and network meta-analysis. American Journal of Obstetrics and Gynecology, 1(214), pp.S248-S249.

Jarde, A., Lutsiv, O., Park, C., Shah, P., Biringer, A., Saito, S., Cook, J., Vera, C., Barret, J., Chamberlain, J. and Dodd, J., 2016. P-OBS-JM-077 What is the Best Intervention for Preventing Preterm Birth: Progesterone, Cerclage or Pessary? A Systematic Review and Network Meta-analysis. Journal of Obstetrics and Gynaecology Canada, 38(5), p.489.

Chamberlain, J. and E. Nakabembe. (2016) Water: A Missing Link That Can Save Mothers and Newborns. Solutions 7(6):40-46.

Nakabembe, E., Chamberlain, J., Ssonko, M., Mirembe, F., Scott, D. and Agutu, T., 2015. Bridging the communication gap between communities and health facilities using modern accessible technology with information power for improved care of vulnerable mothers and newborns. Canadian Journal of Surgery, 58(4 Suppl 1), p.S165.

Chamberlain, J. and Nakabembe, E., 2015. Moving Goals and Policy Into Effective Action for Mothers and Newborns Around the World: the Mother-and Baby-Friendly Hospital Initiative. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.14-15.

Chamberlain, J. and Watt, S., 2012. Training multidisciplinary leaders for health promotion in developing countries: lessons learned. Health promotion practice, 13(3), pp.344-348.

Watt, S., and Chamberlain, J., 2012. Training and Retaining Effective Safe Motherhood Advocates. Interdisciplinary Studies Journal, 1(4), p.9.

Watt, S. and Chamberlain, J., 2011. Water, climate change, and maternal and newborn health. Current Opinion in Environmental Sustainability, 3(6), pp.491-496.

Chamberlain, J. and Watt, S., 2008. Education for safe motherhood: a Save the Mothers’ advocacy initiative. Leadership in Health Services, 21(4), pp.278-289.

Chamberlain, J., Watt, S., Mohide, P., Muggah, H., Trim, K. and Kyomuhendo, G.B., 2007. Women’s perception of self-worth and access to health care. International Journal of Gynecology & Obstetrics, 98(1), pp.75-79.

Chamberlain JE. (2004). Compassion in Life, Caring in Death.(editorial).  JOGC July 2004 26 (7): 621.

Chamberlain JE, Lalonde A, Sarulkarum A, McDonagh R. The Role of Professional Associations in Reducing Maternal Mortality. Int. J. of Gyencol Obstet 2003: 83 (1):94-102.

Chamberlain, JE. From Fistula Patient to Fistula Surgeon. JOGC, February 2003

Thistle PJ, Chamberlain J. Vaginal Birth after Cesarean Section in Rural African Setting. Int. J. of Gynecology and Obstetrics, 77, April 2002, 31.

BIO

After completing her BSc in biochemistry at the University of Toronto, Dr. Jean Chamberlain attended medical school at the University of Toronto. She earned her MD in 1991 and completed a rotating internship at Toronto East General Hospital in 1992. Upon completion of a Royal College Fellowship in obstetrics and gynecology at the University of Western Ontario in 1996, Dr. Chamberlain joined the Department of Obstetrics & Gynecology at McMaster University. She completed her master of education at the University of Toronto (OISE) in 1998.

Dr. Chamberlain is also co-director of the McMaster International Women’s Health Program and founding director of Save the Mothers (STM) International, an organization dedicated to saving some of the 287,000 mothers who die in childbirth every year. Dr. Chamberlain is an internationally recognized expert in women’s health and is a member of the Order of Canada. Her work has earned her several awards including the 2006 International Community Service Award from the Federation of International Obstetricians/Gynecologists for her outstanding contribution to the health of mothers around the world.

Dr. Chamberlain also received the Teasdale-Corti Humanitarian Award from the Royal College of Physicians and Surgeons of Canada in 2009.

She has spent 12 years working in Uganda advocating for safe motherhood with Save the Mothers. Before her tenure in Uganda, she spent five years in Yemen as an obstetrician/gynecologist. While abroad, she maintained her academic position in obstetrics and gynecology at McMaster University. Currently, she is a professor at McMaster University with her clinical practice based out of St Joseph’s Hospital Hamilton.

RESEARCH INTERESTS

International women’s health, public health leadership, advocacy, refugee and immigrant women

HONOURS & AWARDS

• International Community Service Award, Federation of International Obstetricians/Gynecologists (2006)
• Teasdale-Corti Humanitarian Award for work improving maternal health, Royal College of Physicians and Surgeons of Canada (2009)
• Prix d’Excellence for going beyond the call of duty, Royal College of Physicians and Surgeons of Canada (2012)
• Queen Elizabeth II Diamond Jubilee medal (2012)
• Iductee, Hamilton Gallery of Distinction (2013)
• Mission Legacy Award, The Sisters of St. Joseph, Hamilton (2013)
• Honorary Doctorate of Laws, University of Waterloo (2013)
• Member, Order of Canada (2014)

PUBLICATIONS

Jarde, A., Lutsiv, O., Park, C.K., Beyene, J., Dodd, J.M., Barrett, J., Shah, P.S., Cook, J.L., Saito, S., Biringer, A.B. and Sabatino, L., 2017. Effectiveness of progesterone, cerclage and pessary for preventing preterm birth in singleton pregnancies: a systematic review and network meta-analysis. BJOG: An International Journal of Obstetrics & Gynaecology.

Jarde, A., Lutsiv, O., Park, C., Gulmezoglu, M., Shah, P., Biringer, A., Saito, S., Cook, J., Vera, C., Barrett, J. and Chamberlain, J., 2016. Progesterone, cervical cerclage and cervical pessary for primary prevention of preterm birth in high risk singleton pregnancies: a systematic review and network meta-analysis. American Journal of Obstetrics and Gynecology, 1(214), pp.S248-S249.

Jarde, A., Lutsiv, O., Park, C., Shah, P., Biringer, A., Saito, S., Cook, J., Vera, C., Barret, J., Chamberlain, J. and Dodd, J., 2016. P-OBS-JM-077 What is the Best Intervention for Preventing Preterm Birth: Progesterone, Cerclage or Pessary? A Systematic Review and Network Meta-analysis. Journal of Obstetrics and Gynaecology Canada, 38(5), p.489.

Chamberlain, J. and E. Nakabembe. (2016) Water: A Missing Link That Can Save Mothers and Newborns. Solutions 7(6):40-46.

Nakabembe, E., Chamberlain, J., Ssonko, M., Mirembe, F., Scott, D. and Agutu, T., 2015. Bridging the communication gap between communities and health facilities using modern accessible technology with information power for improved care of vulnerable mothers and newborns. Canadian Journal of Surgery, 58(4 Suppl 1), p.S165.

Chamberlain, J. and Nakabembe, E., 2015. Moving Goals and Policy Into Effective Action for Mothers and Newborns Around the World: the Mother-and Baby-Friendly Hospital Initiative. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.14-15.

Chamberlain, J. and Watt, S., 2012. Training multidisciplinary leaders for health promotion in developing countries: lessons learned. Health promotion practice, 13(3), pp.344-348.

Watt, S., and Chamberlain, J., 2012. Training and Retaining Effective Safe Motherhood Advocates. Interdisciplinary Studies Journal, 1(4), p.9.

Watt, S. and Chamberlain, J., 2011. Water, climate change, and maternal and newborn health. Current Opinion in Environmental Sustainability, 3(6), pp.491-496.

Chamberlain, J. and Watt, S., 2008. Education for safe motherhood: a Save the Mothers’ advocacy initiative. Leadership in Health Services, 21(4), pp.278-289.

Chamberlain, J., Watt, S., Mohide, P., Muggah, H., Trim, K. and Kyomuhendo, G.B., 2007. Women’s perception of self-worth and access to health care. International Journal of Gynecology & Obstetrics, 98(1), pp.75-79.

Chamberlain JE. (2004). Compassion in Life, Caring in Death.(editorial).  JOGC July 2004 26 (7): 621.

Chamberlain JE, Lalonde A, Sarulkarum A, McDonagh R. The Role of Professional Associations in Reducing Maternal Mortality. Int. J. of Gyencol Obstet 2003: 83 (1):94-102.

Chamberlain, JE. From Fistula Patient to Fistula Surgeon. JOGC, February 2003

Thistle PJ, Chamberlain J. Vaginal Birth after Cesarean Section in Rural African Setting. Int. J. of Gynecology and Obstetrics, 77, April 2002, 31.

BIO

After completing her BSc with honours at the University of Toronto in 1992, Dr. Ann Marie Chen began medical school at the University of Toronto. In 1996, she entered a residency in obstetrics and oynecology at McMaster University and, in 2001, joined the department.

Dr. Chen is an assistant clinical professor and active staff in the Department of Obstetrics & Gynecology at Hamilton Health Sciences Corporation.

AWARDS

• 2015 American College of Obstetricians and Gynecologists (CREOG) National Faculty Award for Excellence in Resident Education, McMaster University, OBGYN Dept
• 2018 Excellence in Resident Teaching, McMaster University, Department of Obstetrics & Gynecology

PUBLICATIONS

McDonald, S.D., Pullenayegum, E., Bracken, K., Chen, A.M., McDonald, H., Malott, A., Hutchison, R., Haley, S., Lutsiv, O., Taylor, V.H. and Good, C., 2012. Comparison of midwifery, family medicine, and obstetric patients’ understanding of weight gain during pregnancy: a minority of women report correct counselling. Journal of Obstetrics and Gynaecology Canada, 34(2), pp.129-135.

McDonald, S.D., Pullenayegum, E., Taylor, V., Lutsiv, O., Bracken, K., Good, C., Hutton, E., Chen, A.M., Hutchison, R., Malott, A. and McDonald, H., 2011. 182-Three-quarters of overweight and obese women are planning on exceeding the gestational weight gain recommendations. Canadian Journal of Diabetes, 35(2), p.187.

BIO

After completing her BSc with honours at the University of Toronto in 1992, Dr. Ann Marie Chen began medical school at the University of Toronto. In 1996, she entered a residency in obstetrics and oynecology at McMaster University and, in 2001, joined the department.

Dr. Chen is an assistant clinical professor and active staff in the Department of Obstetrics & Gynecology at Hamilton Health Sciences Corporation.

AWARDS

• 2015 American College of Obstetricians and Gynecologists (CREOG) National Faculty Award for Excellence in Resident Education, McMaster University, OBGYN Dept
• 2018 Excellence in Resident Teaching, McMaster University, Department of Obstetrics & Gynecology

PUBLICATIONS

McDonald, S.D., Pullenayegum, E., Bracken, K., Chen, A.M., McDonald, H., Malott, A., Hutchison, R., Haley, S., Lutsiv, O., Taylor, V.H. and Good, C., 2012. Comparison of midwifery, family medicine, and obstetric patients’ understanding of weight gain during pregnancy: a minority of women report correct counselling. Journal of Obstetrics and Gynaecology Canada, 34(2), pp.129-135.

McDonald, S.D., Pullenayegum, E., Taylor, V., Lutsiv, O., Bracken, K., Good, C., Hutton, E., Chen, A.M., Hutchison, R., Malott, A. and McDonald, H., 2011. 182-Three-quarters of overweight and obese women are planning on exceeding the gestational weight gain recommendations. Canadian Journal of Diabetes, 35(2), p.187.

RESEARCH INTERESTS

• Burnout

Research Themes

Minimally invasive gynecology; Minimally invasive surgery; Hysterectomy; Laparoscopy

FEATURED PUBLICATIONS

Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. (2017). Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. Journal of Obstetrics and Gynaecology Canada.

Arendas, K., Coll-Black, M. and Leyland, N.A., 2015. Approach to the Obliterated Posterior Cul-De-Sac. Journal of Minimally Invasive Gynecology, 22(6), p.S120.

RESEARCH INTERESTS

• Burnout

Research Themes

Minimally invasive gynecology; Minimally invasive surgery; Hysterectomy; Laparoscopy

FEATURED PUBLICATIONS

Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. (2017). Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. Journal of Obstetrics and Gynaecology Canada.

Arendas, K., Coll-Black, M. and Leyland, N.A., 2015. Approach to the Obliterated Posterior Cul-De-Sac. Journal of Minimally Invasive Gynecology, 22(6), p.S120.

BIO

Dr. Dustin Costescu is an academic generalist, family planning specialist in the Department of Obstetrics & Gynecology at McMaster University. Dr. Costescu completed his Bsc at the University of Guelph, his doctorate of medicine from the University of Western Ontario and his obstetrics and gynaecology residency at McMaster University. Dr. Costescu also completed a fellowship in contraception advice research and education from Queen’s University.

Clinical, Educational and Administrative Work

Dr. Costescu’s clinical practice focuses in contraceptive care, family planning, colposcopy and sexual medicine, in addition to general OB/Gyn complaints. Dr. Costescu teaches medical students, residents and allied health professionals in many of these areas, and is an invited lecturer locally, nationally and internationally as a family planning expert. Dr. Costescu is the current continuing education director for the department.

RESEARCH INTERESTS

Dr. Costescu’s research focuses on contraception and family planning. Currently, the following areas are being investigated:

• Family planning need and contraceptive use in special populations
• Contraceptive decision-making
• Qualitative experiences of unintended pregnancy and abortion, both for women and men involved in the pregnancy
• Optimizing contraceptive care

PUBLICATIONS

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2017. No. 329-Canadian Contraception Consensus Part 4 of 4 Chapter 9: Combined Hormonal Contraception. Journal of Obstetrics and Gynaecology Canada, 39(4), pp.229-268.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2017. Consensus canadien sur la contraception (4 e partie de 4): chapitre 9–contraception hormonale combinée. Journal of Obstetrics and Gynaecology Canada, 39(4), pp.269-314.

Syan, S.K., Minuzzi, L., Costescu, D., Smith, M., Allega, O.R., Coote, M., Hall, G.B. and Frey, B.N., 2017. Influence of endogenous estradiol, progesterone, allopregnanolone, and dehydroepiandrosterone sulfate on brain resting state functional connectivity across the menstrual cycle. Fertility and Sterility, 107(5), pp.1246-1255.

Dylan Ehman, MD, MSc; Dustin Costescu MD, FRCSC Tubal Sterilization in Women Uner 30: Case Series and Ethical Implications JOGC 2017 Sept; .doi: 10.1016/j.jogc.2017.05.034

Persadie, R.J., Costescu-Green, D. and Gerster, K.M., 2016. Cervical Ectopic Pregnancy Complicated by Escherichia Coli Septicemia: A Case Report

Ferguson, C.A., Costescu, D., Jamieson, M.A. and Jong, L., 2016. Transmural migration and perforation of a levonorgestrel intrauterine system: a case report and review of the literature.

Liauw, J., Foran, J., Dineley, B., Costescu, D. and Kouyoumdjian, F.G., 2016. The Unmet Contraceptive Need of Incarcerated Women in Ontario

Soon, J.A., Costescu, D. and Guilbert, E., 2016. Medications Used in Evidence-Based Regimens for Medical Abortion: An Overview. Journal of Obstetrics and Gynaecology Canada, 38(7), pp.636-645.

Costescu, D., Guilbert, E., Bernardin, J., Black, A., Dunn, S., Fitzsimmons, B., Norman, W.V., Pymar, H., Soon, J., Trouton, K. and Wagner, M.S., 2016. Medical abortion. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.366-389.

Costescu, D.J., 2016. Levonorgestrel-releasing intrauterine systems for long-acting contraception: current perspectives, safety, and patient counseling. International journal of women’s health, 8, p.589.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (2e partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(11), pp.1036-1039.

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Blake, J., Waddington, A., Black, D., Brown, V., Costescu, D., Mangat, R., Rittenberg, D., Leboeuf, M., Malhotra, U., Fisher, W. and Cook, J., 2016. Intrauterine contraception: Build your expertise intrauterine contraceptive health Practitioner/patient Audit Program. Bjog: An International Journal of Obstetrics and Gynaecology, 123, pp.47-48.

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W., Pymar, H., Reid, R. and Roy, G., 2016. Canadian Contraception Consensus (Part 3 of 4): Chapter 8–Progestin-Only Contraception. Journal of Obstetrics and Gynaecology Canada, 38(3), pp.279-300.

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Costescu, D., Liauw, J. and Dineley, B., Abortion training in Canadian obstetrics and gynaecology residency programmes. Book of Abstracts, The European Journal of Contraception & Reproductive Health Care, 21:sup1, p.101

Liauw, J., Dineley, B., Gerster, K., Hill, N. and Costescu, D., 2016. Abortion training in Canadian obstetrics and gynecology residency programs. Contraception, 94(5), pp.478-482.

Costescu, D., Guilbert, É., Bernardin, J., Black, A., Dunn, S., Fitzsimmons, B., Norman, W.V., Pymar, H., Soon, J., Trouton, K. and Wagner, M.S., 2016. Avortement médical. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.390-420.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W., Pymar, H., Reid, R. and Roy, G., 2016. Canadian contraception consensus (part 3 of 4): chapter 7–intrauterine contraception. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.182-222.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Canadian contraception consensus (part 1 of 4). Journal of Obstetrics and Gynaecology Canada, 37(10), pp.936-938.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (1 re partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(10), pp.939-942.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (2e partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(11), pp.1036-1039.

Hauck, B. and Costescu, D., 2015. Barriers and misperceptions limiting widespread use of intrauterine contraception among Canadian women. Journal of Obstetrics and Gynaecology Canada, 37(7), pp.606-616.

Costescu, D.J. and Waddington, A., 2013. Any review must carefully weigh the available evidence. BMJ, 346, p.f2250.

Costescu, D.J. and Cullimore, A.J., 2013. Lessons learned from a resident-led clinical trial in obstetrics. Clinical Trials, 10(4), pp.612-616.

Costescu, D.J. and Lamont, J.A., 2013. Understanding the pregnancy decision-making process among couples seeking induced abortion. Journal of Obstetrics and Gynaecology Canada, 35(10), pp.899-904.

BIO

Dr. Dustin Costescu is an academic generalist, family planning specialist in the Department of Obstetrics & Gynecology at McMaster University. Dr. Costescu completed his Bsc at the University of Guelph, his doctorate of medicine from the University of Western Ontario and his obstetrics and gynaecology residency at McMaster University. Dr. Costescu also completed a fellowship in contraception advice research and education from Queen’s University.

Clinical, Educational and Administrative Work

Dr. Costescu’s clinical practice focuses in contraceptive care, family planning, colposcopy and sexual medicine, in addition to general OB/Gyn complaints. Dr. Costescu teaches medical students, residents and allied health professionals in many of these areas, and is an invited lecturer locally, nationally and internationally as a family planning expert. Dr. Costescu is the current continuing education director for the department.

RESEARCH INTERESTS

Dr. Costescu’s research focuses on contraception and family planning. Currently, the following areas are being investigated:

• Family planning need and contraceptive use in special populations
• Contraceptive decision-making
• Qualitative experiences of unintended pregnancy and abortion, both for women and men involved in the pregnancy
• Optimizing contraceptive care

PUBLICATIONS

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2017. No. 329-Canadian Contraception Consensus Part 4 of 4 Chapter 9: Combined Hormonal Contraception. Journal of Obstetrics and Gynaecology Canada, 39(4), pp.229-268.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2017. Consensus canadien sur la contraception (4 e partie de 4): chapitre 9–contraception hormonale combinée. Journal of Obstetrics and Gynaecology Canada, 39(4), pp.269-314.

Syan, S.K., Minuzzi, L., Costescu, D., Smith, M., Allega, O.R., Coote, M., Hall, G.B. and Frey, B.N., 2017. Influence of endogenous estradiol, progesterone, allopregnanolone, and dehydroepiandrosterone sulfate on brain resting state functional connectivity across the menstrual cycle. Fertility and Sterility, 107(5), pp.1246-1255.

Dylan Ehman, MD, MSc; Dustin Costescu MD, FRCSC Tubal Sterilization in Women Uner 30: Case Series and Ethical Implications JOGC 2017 Sept; .doi: 10.1016/j.jogc.2017.05.034

Persadie, R.J., Costescu-Green, D. and Gerster, K.M., 2016. Cervical Ectopic Pregnancy Complicated by Escherichia Coli Septicemia: A Case Report

Ferguson, C.A., Costescu, D., Jamieson, M.A. and Jong, L., 2016. Transmural migration and perforation of a levonorgestrel intrauterine system: a case report and review of the literature.

Liauw, J., Foran, J., Dineley, B., Costescu, D. and Kouyoumdjian, F.G., 2016. The Unmet Contraceptive Need of Incarcerated Women in Ontario

Soon, J.A., Costescu, D. and Guilbert, E., 2016. Medications Used in Evidence-Based Regimens for Medical Abortion: An Overview. Journal of Obstetrics and Gynaecology Canada, 38(7), pp.636-645.

Costescu, D., Guilbert, E., Bernardin, J., Black, A., Dunn, S., Fitzsimmons, B., Norman, W.V., Pymar, H., Soon, J., Trouton, K. and Wagner, M.S., 2016. Medical abortion. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.366-389.

Costescu, D.J., 2016. Levonorgestrel-releasing intrauterine systems for long-acting contraception: current perspectives, safety, and patient counseling. International journal of women’s health, 8, p.589.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (2e partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(11), pp.1036-1039.

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Blake, J., Waddington, A., Black, D., Brown, V., Costescu, D., Mangat, R., Rittenberg, D., Leboeuf, M., Malhotra, U., Fisher, W. and Cook, J., 2016. Intrauterine contraception: Build your expertise intrauterine contraceptive health Practitioner/patient Audit Program. Bjog: An International Journal of Obstetrics and Gynaecology, 123, pp.47-48.

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W., Pymar, H., Reid, R. and Roy, G., 2016. Canadian Contraception Consensus (Part 3 of 4): Chapter 8–Progestin-Only Contraception. Journal of Obstetrics and Gynaecology Canada, 38(3), pp.279-300.

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Costescu, D., Liauw, J. and Dineley, B., Abortion training in Canadian obstetrics and gynaecology residency programmes. Book of Abstracts, The European Journal of Contraception & Reproductive Health Care, 21:sup1, p.101

Liauw, J., Dineley, B., Gerster, K., Hill, N. and Costescu, D., 2016. Abortion training in Canadian obstetrics and gynecology residency programs. Contraception, 94(5), pp.478-482.

Costescu, D., Guilbert, É., Bernardin, J., Black, A., Dunn, S., Fitzsimmons, B., Norman, W.V., Pymar, H., Soon, J., Trouton, K. and Wagner, M.S., 2016. Avortement médical. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.390-420.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W., Pymar, H., Reid, R. and Roy, G., 2016. Canadian contraception consensus (part 3 of 4): chapter 7–intrauterine contraception. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.182-222.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Canadian contraception consensus (part 1 of 4). Journal of Obstetrics and Gynaecology Canada, 37(10), pp.936-938.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (1 re partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(10), pp.939-942.

Black, A., Guilbert, E., Costescu, D., Dunn, S., Fisher, W., Kives, S., Mirosh, M., Norman, W.V., Pymar, H., Reid, R. and Roy, G., 2015. Consensus canadien sur la contraception (2e partie de 4). Journal of Obstetrics and Gynaecology Canada, 37(11), pp.1036-1039.

Hauck, B. and Costescu, D., 2015. Barriers and misperceptions limiting widespread use of intrauterine contraception among Canadian women. Journal of Obstetrics and Gynaecology Canada, 37(7), pp.606-616.

Costescu, D.J. and Waddington, A., 2013. Any review must carefully weigh the available evidence. BMJ, 346, p.f2250.

Costescu, D.J. and Cullimore, A.J., 2013. Lessons learned from a resident-led clinical trial in obstetrics. Clinical Trials, 10(4), pp.612-616.

Costescu, D.J. and Lamont, J.A., 2013. Understanding the pregnancy decision-making process among couples seeking induced abortion. Journal of Obstetrics and Gynaecology Canada, 35(10), pp.899-904.

BIO

Dr. Crankshaw is a professor emeritus at McMaster University and continues to participate in basic research projects both at McMaster and at the National University of Ireland, Galway.

He is a pharmacologist with interests in basic research and drug discovery. For eight years Dr. Crankshaw was the director of the honours biology and pharmacology program at McMaster University. His BSc from the University of London and PhD from the University of Alberta are both in pharmacology. He also did post-doctoral work at the Swiss Federal Institute of Technology (ETH Zürich) and has taken research leaves at the University of Manchester, Astra Pain Discovery Unit Sweden, AstraZeneca Pharmaceuticals, Wilmington, DE and the National University of Ireland, Galway.

AWARDS

• McMaster University Students’ Union Award for Teaching Excellence, Faculty of Health Sciences, 1997
• McMaster University Students’ Union Award for Teaching Excellence, Faculty of Health Sciences, 2005

RESEARCH INTERESTS

Dr. Crankshaw’s research interests are currently focused almost exclusively on aspect of human myometrial function:

• Operational and analytical pharmacology of human myometrium in vitro
• Development of novel treatments for preterm labour and post-partum hemorrhage
• Understanding the underlying causes of poor uterine contractility during labour

Research Themes

Human myometrium; Contractility; Preterm labour; Pharmacology; Post partum haemorrhage

PUBLICATIONS

Crankshaw, D.J., Crosby, D.A. and Morrison, J.J., 2017. Effects of the KIR7. 1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium. Reproductive Sciences, p.1933719116687657.

Crosby, D.A., Crankshaw, D.J. and Morrison, J.J., 2016. 202: Human myometrial in vitro effects of pharmacological agents used in the clinical management of postpartum hemorrhage. American Journal of Obstetrics & Gynecology, 214(1), pp.S122-S123.

Morrison, J.J., Crosby, D.A. and Crankshaw, D.J., 2016. In vitro contractile effects of agents used in the clinical management of postpartum haemorrhage. European journal of pharmacology, 789, pp.328-333.

Morrison, J.J., Sweeney, E.M., Crosby, D.A., Crankshaw, D.J. and Dockery, P., 2016. The mitochondrion and uterine myocyte senescence in human pregnant myometrium: implications for labor and maternal age. American Journal of Obstetrics & Gynecology, 214(1), p.S214.

Crankshaw, D.J., O’Brien, Y.M., Crosby, D.A. and Morrison, J.J., 2015. Maternal age and contractility of human myometrium in pregnancy. Reproductive Sciences, 22(10), pp.1229-1235.

Sweeney, E.M., Scully, D., Black, A., Crankshaw, D.J., O’brien, Y., Dockery, P. and Morrison, J.J., 2014. An analysis of connexin 43 expression in term myometrium and the effect of maternal Bmi and age. Journal of Anatomy, 224(2), p.243.

Crankshaw, D.J., Sweeney, E.M., Walsh, J.M., Dockery, P. and Morrison, J.J., 2014. The influence of smooth muscle content and orientation in dissected human pregnant myometrial strips on contractility measurements. European journal of pharmacology, 738, pp.245-249.

Crankshaw, D.J., Walsh, J.M. and Morrison, J.J., 2014. The effects of methyl palmitate, a putative regulator from perivascular fat, on the contractility of pregnant human myometrium. Life sciences, 116(1), pp.25-30.

Sweeney, E.M., Morrison, J.J., Crankshaw, D.J., O’Brien, Y.M. and Dockery, P., 2014, March. Reduced Mitochondrial Content in Pregnant Myometrium from Older Mothers. Reproductive Sciences (Vol. 21, No. 3, pp. 341A-342A).

Sweeney, E.M., Dockery, P., Crankshaw, D.J., O’brien, Y.M., Walsh, J.M. and Morrison, J.J., 2014. Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age. Journal of anatomy, 225(6), pp.625-633.

McNulty, J., Keskar, K., Crankshaw, D.J. and Holloway, A.C., 2014. Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic & medicinal chemistry letters, 24(18), pp.4586-4589.

Sweeney, E.M., Morrison, J.J., Crankshaw, D.J., Walsh, J.M. and Dockery, P., 2014, March. Increased Surface to Volume Ratio in Pregnant Myometrial Smooth Muscle from Older Mothers. Reproductive Sciences (Vol. 21, No. 3, pp. 342A-342A).

Crankshaw, D.J., Pistilli, M.J., O’Brien, Y.M., Sweeney, E.M., Dockery, P., Holloway, A.C. and Morrison, J.J., 2013. The effects of extracellular calcium-sensing receptor ligands on the contractility of pregnant human myometrium in vitro. Reproductive sciences, p.1933719112468949.

McNulty, J., Nielsen, A.J., Brown, C.E., DiFrancesco, B.R., Vurgun, N., Nair, J.J., Crankshaw, D.J. and Holloway, A.C., 2013. Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 23(22), pp.6060-6063.

Sweeney, E.M., Crankshaw, D.J., O’brien, Y., Dockery, P. and Morrison, J.J., 2013. Stereology of human myometrium in pregnancy: influence of maternal body mass index and age. American journal of obstetrics and gynecology, 208(4), pp.324-e1.

Sweeney, E., Crankshaw, D., O’brien, Y., Dockery, P. and Morrison, J., 2013. 308: Stereological analysis of human myometrium in third trimester pregnancy: influence of maternal age, body mass index and parity. American Journal of Obstetrics & Gynecology, 208(1), p.S139.

Pistilli, M.J., Petrik, J.J., Holloway, A.C. and Crankshaw, D.J., 2012. Immunohistochemical and functional studies on calcium?sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology, 39(1), pp.37-42.

McNulty, J., Nair, J.J., Vurgun, N., DiFrancesco, B.R., Brown, C.E., Tsoi, B., Crankshaw, D.J. and Holloway, A.C., 2012. Discovery of a novel class of aldol-derived 1, 2, 3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 22(1), pp.718-722.

Holloway AC, Anger DA, Crankshaw DJ, Wu M, Foster WG. (2007). Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. J. Appl. Toxicol.,.28: 260-270.

BIO

Dr. Crankshaw is a professor emeritus at McMaster University and continues to participate in basic research projects both at McMaster and at the National University of Ireland, Galway.

He is a pharmacologist with interests in basic research and drug discovery. For eight years Dr. Crankshaw was the director of the honours biology and pharmacology program at McMaster University. His BSc from the University of London and PhD from the University of Alberta are both in pharmacology. He also did post-doctoral work at the Swiss Federal Institute of Technology (ETH Zürich) and has taken research leaves at the University of Manchester, Astra Pain Discovery Unit Sweden, AstraZeneca Pharmaceuticals, Wilmington, DE and the National University of Ireland, Galway.

AWARDS

• McMaster University Students’ Union Award for Teaching Excellence, Faculty of Health Sciences, 1997
• McMaster University Students’ Union Award for Teaching Excellence, Faculty of Health Sciences, 2005

RESEARCH INTERESTS

Dr. Crankshaw’s research interests are currently focused almost exclusively on aspect of human myometrial function:

• Operational and analytical pharmacology of human myometrium in vitro
• Development of novel treatments for preterm labour and post-partum hemorrhage
• Understanding the underlying causes of poor uterine contractility during labour

Research Themes

Human myometrium; Contractility; Preterm labour; Pharmacology; Post partum haemorrhage

PUBLICATIONS

Crankshaw, D.J., Crosby, D.A. and Morrison, J.J., 2017. Effects of the KIR7. 1 Blocker VU590 on Spontaneous and Agonist-Induced Contractions of Human Pregnant Myometrium. Reproductive Sciences, p.1933719116687657.

Crosby, D.A., Crankshaw, D.J. and Morrison, J.J., 2016. 202: Human myometrial in vitro effects of pharmacological agents used in the clinical management of postpartum hemorrhage. American Journal of Obstetrics & Gynecology, 214(1), pp.S122-S123.

Morrison, J.J., Crosby, D.A. and Crankshaw, D.J., 2016. In vitro contractile effects of agents used in the clinical management of postpartum haemorrhage. European journal of pharmacology, 789, pp.328-333.

Morrison, J.J., Sweeney, E.M., Crosby, D.A., Crankshaw, D.J. and Dockery, P., 2016. The mitochondrion and uterine myocyte senescence in human pregnant myometrium: implications for labor and maternal age. American Journal of Obstetrics & Gynecology, 214(1), p.S214.

Crankshaw, D.J., O’Brien, Y.M., Crosby, D.A. and Morrison, J.J., 2015. Maternal age and contractility of human myometrium in pregnancy. Reproductive Sciences, 22(10), pp.1229-1235.

Sweeney, E.M., Scully, D., Black, A., Crankshaw, D.J., O’brien, Y., Dockery, P. and Morrison, J.J., 2014. An analysis of connexin 43 expression in term myometrium and the effect of maternal Bmi and age. Journal of Anatomy, 224(2), p.243.

Crankshaw, D.J., Sweeney, E.M., Walsh, J.M., Dockery, P. and Morrison, J.J., 2014. The influence of smooth muscle content and orientation in dissected human pregnant myometrial strips on contractility measurements. European journal of pharmacology, 738, pp.245-249.

Crankshaw, D.J., Walsh, J.M. and Morrison, J.J., 2014. The effects of methyl palmitate, a putative regulator from perivascular fat, on the contractility of pregnant human myometrium. Life sciences, 116(1), pp.25-30.

Sweeney, E.M., Morrison, J.J., Crankshaw, D.J., O’Brien, Y.M. and Dockery, P., 2014, March. Reduced Mitochondrial Content in Pregnant Myometrium from Older Mothers. Reproductive Sciences (Vol. 21, No. 3, pp. 341A-342A).

Sweeney, E.M., Dockery, P., Crankshaw, D.J., O’brien, Y.M., Walsh, J.M. and Morrison, J.J., 2014. Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age. Journal of anatomy, 225(6), pp.625-633.

McNulty, J., Keskar, K., Crankshaw, D.J. and Holloway, A.C., 2014. Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic & medicinal chemistry letters, 24(18), pp.4586-4589.

Sweeney, E.M., Morrison, J.J., Crankshaw, D.J., Walsh, J.M. and Dockery, P., 2014, March. Increased Surface to Volume Ratio in Pregnant Myometrial Smooth Muscle from Older Mothers. Reproductive Sciences (Vol. 21, No. 3, pp. 342A-342A).

Crankshaw, D.J., Pistilli, M.J., O’Brien, Y.M., Sweeney, E.M., Dockery, P., Holloway, A.C. and Morrison, J.J., 2013. The effects of extracellular calcium-sensing receptor ligands on the contractility of pregnant human myometrium in vitro. Reproductive sciences, p.1933719112468949.

McNulty, J., Nielsen, A.J., Brown, C.E., DiFrancesco, B.R., Vurgun, N., Nair, J.J., Crankshaw, D.J. and Holloway, A.C., 2013. Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 23(22), pp.6060-6063.

Sweeney, E.M., Crankshaw, D.J., O’brien, Y., Dockery, P. and Morrison, J.J., 2013. Stereology of human myometrium in pregnancy: influence of maternal body mass index and age. American journal of obstetrics and gynecology, 208(4), pp.324-e1.

Sweeney, E., Crankshaw, D., O’brien, Y., Dockery, P. and Morrison, J., 2013. 308: Stereological analysis of human myometrium in third trimester pregnancy: influence of maternal age, body mass index and parity. American Journal of Obstetrics & Gynecology, 208(1), p.S139.

Pistilli, M.J., Petrik, J.J., Holloway, A.C. and Crankshaw, D.J., 2012. Immunohistochemical and functional studies on calcium?sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology, 39(1), pp.37-42.

McNulty, J., Nair, J.J., Vurgun, N., DiFrancesco, B.R., Brown, C.E., Tsoi, B., Crankshaw, D.J. and Holloway, A.C., 2012. Discovery of a novel class of aldol-derived 1, 2, 3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 22(1), pp.718-722.

Holloway AC, Anger DA, Crankshaw DJ, Wu M, Foster WG. (2007). Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues. J. Appl. Toxicol.,.28: 260-270.

BIO

Dr. Amie Cullimore is a professor emeritus of obstetrics and gynecology at McMaster University and a former practicing obstetrician and gynecologist at St. Joseph’s Healthcare.

AWARDS

• 2008, Ontario Hospital Association, Leading Practice Award
• 2007, Association of Professors in Obstetrics and Gynecology of Canada, Carl Nimrod Educator of the Year Award
• 2005, Canadian Association of Medical Education, Certificate of Merit Award
• 2005, Association of Professors in Obstetrics and Gynecology AGM., Best Oral Presentation
• 2004, The Professional Association of Internes and Residents of Ontario (PAIRO) Trust Fund Travel Award for Clinical Educators
• 2004, Association of Professors in Obstetrics and Gynecology (APOG) AGM, Best Poster, 2nd Place
• 2002, Association of Professors of Gynecology and Obstetrics, Excellence in Teaching Award

RESEARCH INTERESTS

Medical Education, Progress Testing in Postgraduate Training

PUBLICATIONS

Abbott, J.F., Pradhan, A., Buery-Joyner, S., Casey, P.M., Chuang, A., Dugoff, L., Dalrymple, J.L., Forstein, D.A., Hampton, B.S., Hueppchen, N.A. and Kaczmarczyk, J.M., 2017. To the Point: Integrating Patient Safety Education Into the Obstetrics and Gynecology Undergraduate Curriculum. Journal of Patient Safety.

Dugoff, L., Pradhan, A., Casey, P., Dalrymple, J.L., Abbott, J.F., Buery-Joyner, S.D., Chuang, A., Cullimore, A.J., Forstein, D.A., Hampton, B.S. and Kaczmarczyk, J.M., 2016. Pelvic and breast examination skills curricula in United States medical schools: a survey of obstetrics and gynecology clerkship directors. BMC Medical Education, 16(1), p.314.

Dalrymple, J.L., Cullimore, A.J., Hiraoka, M., Holmström, S. and Hueppchen, N.A., 2014. Abstracts From the Proceedings of the 2013 Annual Meeting of the Council on Resident Education in Obstetrics and Gynecology (CREOG) and Association of Professors of Gynecology and Obstetrics (APGO). Teaching and learning in medicine, 26(4), pp.431-437.

Hampton, B.S., Chuang, A.W., Abbott, J.F., Buery-Joyner, S.D., Cullimore, A.J., Dalrymple, J.L., Forstein, D.A., Hueppchen, N.A., Kaczmarczyk, J.M., Page-Ramsey, S. and Pradhan, A., 2014. To the point: obstetrics and gynecology global health experiences for medical students. American journal of obstetrics and gynecology, 211(1), pp.18-23.

Costescu, D.J. and Cullimore, A.J., 2013. Lessons learned from a resident-led clinical trial in obstetrics. Clinical Trials, 10(4), pp.612-616.

Kaczmarczyk, J.M., Chuang, A., Dugoff, L., Abbott, J.F., Cullimore, A.J., Dalrymple, J., Davis, K.R., Hueppchen, N.A., Katz, N.T., Nuthalapaty, F.S. and Pradhan, A., 2013. e-Professionalism: A new frontier in medical education. Teaching and learning in medicine, 25(2), pp.165-170.

Nuthalapaty, F.S., Casey, P.M., Cullimore, A.J., Dugoff, L., Abbott, J.F., Chuang, A.W., Dalrymple, J.L., Hueppchen, N.A., Kaczmarczyk, J.M., Katz, N.T. and Pradhan, A., 2012. To the point: a primer on medical education research. American journal of obstetrics and gynecology, 207(1), pp.9-13.

Hueppchen, N., Dalrymple, J.L., Hammoud, M.M., Abbott, J.F., Casey, P.M., Chuang, A.W., Cullimore, A., Davis, K.R., Dugoff, L., Espey, E.L. and Kaczmarczyk, J.M., 2011. To the point: medical education reviews—ongoing call for faculty development. American journal of obstetrics and gynecology, 205(3), pp.171-176.

Dore, K.L., Kreuger, S., Ladhani, M., Rolfson, D., Kurtz, D., Kulasegaram, K., Cullimore, A.J., Norman, G.R., Eva, K.W., Bates, S. and Reiter, H.I., 2010. The reliability and acceptability of the multiple mini-interview as a selection instrument for postgraduate admissions. Academic Medicine, 85(10), pp.S60-S63.

Chuang, A.W., Nuthalapaty, F.S., Casey, P.M., Kaczmarczyk, J.M., Cullimore, A.J., Dalrymple, J.L., Dugoff, L., Espey, E.L., Hammoud, M.M., Hueppchen, N.A. and Katz, N.T., 2010. To the point: reviews in medical education—taking control of the hidden curriculum. American journal of obstetrics and gynecology, 203(4), pp.316-e1.

Cullimore, A.J., Dalrymple, J.L., Dugoff, L., Hueppchen, N.A., Casey, P.M., Chuang, A.W., Espey, E.L., Hammoud, M.M., Kaczmarczyk, J.M., Katz, N.T. and Nuthalapaty, F.S., 2010. The obstetrics and gynaecology resident as teacher. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1176-1185.

BIO

Dr. Amie Cullimore is a professor emeritus of obstetrics and gynecology at McMaster University and a former practicing obstetrician and gynecologist at St. Joseph’s Healthcare.

AWARDS

• 2008, Ontario Hospital Association, Leading Practice Award
• 2007, Association of Professors in Obstetrics and Gynecology of Canada, Carl Nimrod Educator of the Year Award
• 2005, Canadian Association of Medical Education, Certificate of Merit Award
• 2005, Association of Professors in Obstetrics and Gynecology AGM., Best Oral Presentation
• 2004, The Professional Association of Internes and Residents of Ontario (PAIRO) Trust Fund Travel Award for Clinical Educators
• 2004, Association of Professors in Obstetrics and Gynecology (APOG) AGM, Best Poster, 2nd Place
• 2002, Association of Professors of Gynecology and Obstetrics, Excellence in Teaching Award

RESEARCH INTERESTS

Medical Education, Progress Testing in Postgraduate Training

PUBLICATIONS

Abbott, J.F., Pradhan, A., Buery-Joyner, S., Casey, P.M., Chuang, A., Dugoff, L., Dalrymple, J.L., Forstein, D.A., Hampton, B.S., Hueppchen, N.A. and Kaczmarczyk, J.M., 2017. To the Point: Integrating Patient Safety Education Into the Obstetrics and Gynecology Undergraduate Curriculum. Journal of Patient Safety.

Dugoff, L., Pradhan, A., Casey, P., Dalrymple, J.L., Abbott, J.F., Buery-Joyner, S.D., Chuang, A., Cullimore, A.J., Forstein, D.A., Hampton, B.S. and Kaczmarczyk, J.M., 2016. Pelvic and breast examination skills curricula in United States medical schools: a survey of obstetrics and gynecology clerkship directors. BMC Medical Education, 16(1), p.314.

Dalrymple, J.L., Cullimore, A.J., Hiraoka, M., Holmström, S. and Hueppchen, N.A., 2014. Abstracts From the Proceedings of the 2013 Annual Meeting of the Council on Resident Education in Obstetrics and Gynecology (CREOG) and Association of Professors of Gynecology and Obstetrics (APGO). Teaching and learning in medicine, 26(4), pp.431-437.

Hampton, B.S., Chuang, A.W., Abbott, J.F., Buery-Joyner, S.D., Cullimore, A.J., Dalrymple, J.L., Forstein, D.A., Hueppchen, N.A., Kaczmarczyk, J.M., Page-Ramsey, S. and Pradhan, A., 2014. To the point: obstetrics and gynecology global health experiences for medical students. American journal of obstetrics and gynecology, 211(1), pp.18-23.

Costescu, D.J. and Cullimore, A.J., 2013. Lessons learned from a resident-led clinical trial in obstetrics. Clinical Trials, 10(4), pp.612-616.

Kaczmarczyk, J.M., Chuang, A., Dugoff, L., Abbott, J.F., Cullimore, A.J., Dalrymple, J., Davis, K.R., Hueppchen, N.A., Katz, N.T., Nuthalapaty, F.S. and Pradhan, A., 2013. e-Professionalism: A new frontier in medical education. Teaching and learning in medicine, 25(2), pp.165-170.

Nuthalapaty, F.S., Casey, P.M., Cullimore, A.J., Dugoff, L., Abbott, J.F., Chuang, A.W., Dalrymple, J.L., Hueppchen, N.A., Kaczmarczyk, J.M., Katz, N.T. and Pradhan, A., 2012. To the point: a primer on medical education research. American journal of obstetrics and gynecology, 207(1), pp.9-13.

Hueppchen, N., Dalrymple, J.L., Hammoud, M.M., Abbott, J.F., Casey, P.M., Chuang, A.W., Cullimore, A., Davis, K.R., Dugoff, L., Espey, E.L. and Kaczmarczyk, J.M., 2011. To the point: medical education reviews—ongoing call for faculty development. American journal of obstetrics and gynecology, 205(3), pp.171-176.

Dore, K.L., Kreuger, S., Ladhani, M., Rolfson, D., Kurtz, D., Kulasegaram, K., Cullimore, A.J., Norman, G.R., Eva, K.W., Bates, S. and Reiter, H.I., 2010. The reliability and acceptability of the multiple mini-interview as a selection instrument for postgraduate admissions. Academic Medicine, 85(10), pp.S60-S63.

Chuang, A.W., Nuthalapaty, F.S., Casey, P.M., Kaczmarczyk, J.M., Cullimore, A.J., Dalrymple, J.L., Dugoff, L., Espey, E.L., Hammoud, M.M., Hueppchen, N.A. and Katz, N.T., 2010. To the point: reviews in medical education—taking control of the hidden curriculum. American journal of obstetrics and gynecology, 203(4), pp.316-e1.

Cullimore, A.J., Dalrymple, J.L., Dugoff, L., Hueppchen, N.A., Casey, P.M., Chuang, A.W., Espey, E.L., Hammoud, M.M., Kaczmarczyk, J.M., Katz, N.T. and Nuthalapaty, F.S., 2010. The obstetrics and gynaecology resident as teacher. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1176-1185.

BIO

Dr. Rohan D’Souza is an associate professor in the Departments of Obstetrics & Gynecology and Health Research Methods, Evidence and Impact, and a maternal fetal medicine physician at Hamilton Health Sciences. He holds a Canada Research Chair in Maternal Health.

Dr. D’Souza received his MD from the University of Mumbai and his Certificate of Eligibility for Specialist Registration (CESR) from the Royal College of Obstetricians and Gynaecologists (RCOG) in the United Kingdom. He subsequently completed his fellowship training in maternal fetal medicine at Mount Sinai Hospital, University of Toronto and received his PhD and MSc in clinical epidemiology from the Institute for Health Policy, Management and Evaluation at the University of Toronto.

RESEARCH

Dr. D’Souza’s research is focused on improving health outcomes for pregnant women and people with medical disorders and incorporating patient values and preferences into obstetric decision-making. Dr. D’Souza is co-principal investigator on a Canadian Institutes for Health Research (CIHR) funded project looking at the feasibility of establishing a Canadian Obstetric Survey System (CanOSS) for reporting, reviewing and reducing severe health complications in pregnancy.

BIO

Dr. Rohan D’Souza is an associate professor in the Departments of Obstetrics & Gynecology and Health Research Methods, Evidence and Impact, and a maternal fetal medicine physician at Hamilton Health Sciences. He holds a Canada Research Chair in Maternal Health.

Dr. D’Souza received his MD from the University of Mumbai and his Certificate of Eligibility for Specialist Registration (CESR) from the Royal College of Obstetricians and Gynaecologists (RCOG) in the United Kingdom. He subsequently completed his fellowship training in maternal fetal medicine at Mount Sinai Hospital, University of Toronto and received his PhD and MSc in clinical epidemiology from the Institute for Health Policy, Management and Evaluation at the University of Toronto.

RESEARCH

Dr. D’Souza’s research is focused on improving health outcomes for pregnant women and people with medical disorders and incorporating patient values and preferences into obstetric decision-making. Dr. D’Souza is co-principal investigator on a Canadian Institutes for Health Research (CIHR) funded project looking at the feasibility of establishing a Canadian Obstetric Survey System (CanOSS) for reporting, reviewing and reducing severe health complications in pregnancy.

BIO

Dr. Liz Darling is the assistant dean of midwifery at McMaster University and is an associate professor in the Department of Obstetrics & Gynecology. Her qualifications include an honours BArtsSc (McMaster), a BHSc in midwifery (McMaster), an MSc in health research methodology (McMaster) and a PhD in population health (Ottawa).

She holds a Canadian Institutes of Health Research (CIHR) Early Career Investigator Award in Maternal, Reproductive, Child and Youth Health that supports a mixed methods research program investigating the impact of funding expanded midwifery care models in Ontario. She is committed to building research capacity within the midwifery profession and currently mentors undergraduate and graduate students in a variety of academic programs.

Dr. Darling practiced midwifery in Ottawa and was a part-time faculty member with the midwifery education program at Laurentian University prior to joining McMaster full-time in 2017. She is also an adjunct scientist at ICES-McMaster and holds an associate appointment in the Department of Health Research Methods, Evidence & Impact at McMaster University. She has represented the midwifery profession in clinical and research committees at the provincial and national level, including serving as a member of the Expert Advisory Committee for the Canadian Perinatal Surveillance System.

AWARDS

• Canadian Institutes of Health Research (CIHR) Early Career Investigator Award in Maternal, Reproductive, Child and Youth Health (2019)
• Association of Ontario Midwives’ Excellence in Midwifery Research Award (2019)
• Joseph De Koninck Doctoral Thesis Award (2015)
• CIHR Vanier Canada Graduate Scholarship (2011)

RESEARCH INTERESTS

Her research focuses on maternal-newborn health services. Areas of interest include: midwifery services, health disparities, access to care, health policy and perinatal health surveillance. She has particular expertise in the midwifery data collected in Ontario’s perinatal registry (BORN-Ontario).

PUBLICATIONS

Darling, E.K., Ramsay, T., Manuel, D., Sprague, A.E., Walker, M.C. and Guttmann, A., 2017. Association of universal bilirubin screening with socioeconomic disparities in newborn follow-up. Academic pediatrics, 17(2), pp.135-143.

Bhardwaj K, Locke T, Biringer A, Booth A, Darling EK, Dougan S, Harrison J, Hill S, Johnson A, Makin S, Potter B, Lacaze-Masmonteil T, Little J. Newborn bilirubin screening for preventing severe hyperbilirubinemia and bilirubin encephalopathy: a rapid review. Curr Pediatr Rev. 2017 Jan 10. doi: 10.2174/1573396313666170110144345

Dunn S, Sprague A, Grimshaw J, Graham I, Taljaard M, Fell D, et. al.. A mixed methods evaluation of the maternal-newborn dashboard in Ontario: dashboard attributes, contextual factors, and facilitators and barriers to use: a study protocol. Implementation Science 2016; 11:59. doi: 10.1186/s13012-016-0427-1

Dzakpasu, S., Fahey, J., Kirby, R.S., Tough, S.C., Chalmers, B., Heaman, M.I., Bartholomew, S., Biringer, A., Darling, E.K., Lee, L.S. and McDonald, S.D., 2015. Contribution of prepregnancy body mass index and gestational weight gain to adverse neonatal outcomes: population attributable fractions for Canada. BMC pregnancy and childbirth, 15(1), p.21.

Darling, E.K., Ramsay, T., Sprague, A.E., Walker, M.C. and Guttmann, A., 2014. Universal bilirubin screening and health care utilization. Pediatrics, 134(4), pp.e1017-e1024.

Dzakpasu, S., Fahey, J., Kirby, R.S., Tough, S.C., Chalmers, B., Heaman, M.I., Bartholomew, S., Biringer, A., Darling, E.K., Lee, L.S. and McDonald, S.D., 2014. Contribution of prepregnancy body mass index and gestational weight gain to caesarean birth in Canada. BMC pregnancy and childbirth, 14(1), p.106.

Darling, E.K., Guttmann, A., Sprague, A.E., Ramsay, T. and Walker, M.C., 2014. La mise en œuvre des lignes directrices sur l’hyperbilirubinémie de la Société canadienne de pédiatrie: une enquête dans les hôpitaux de l’Ontario. Paediatrics & Child Health, 19(3), pp.133-137.

Darling, E.K., Guttmann, A., Sprague, A.E., Ramsay, T. and Walker, M.C., 2014. Implementation of the Canadian Paediatric Society’s hyperbilirubinemia guidelines: a survey of Ontario hospitals. Paediatrics & child health, 19(3), p.133.

Darling, E.K., 2011. Peer Reviewed Article: Vaginal Birth After Cesarean Section: Outcomes of Women Receiving Midwifery Care in Ontario. Canadian Journal of Midwifery Research & Practice, 10(1), p.9.

Darling, E.K., 2011. Is mandatory neonatal eye prophylaxis ethically justified? a case study from Canada. Public Health Ethics, p.phr016.

O’Brien, B., Chalmers, B., Fell, D., Heaman, M., Darling, E.K. and Herbert, P., 2011. The experience of pregnancy and birth with midwives: results from the Canadian maternity experiences survey. Birth, 38(3), pp.207-215.

Darling E. Vaginal birth after cesarean section: Outcomes of women receiving midwifery care in Ontario. Canadian Journal of Midwifery Research and Practice. 2011; 10(1):9-19.

Darling, E.K., 2011. L’accouchement vaginal après une césarienne: les issues des femmes recevant les soins de sages-femmes en Ontario. Canadian Journal of Midwifery Research & Practice, 10(1), p.20.

Darling, E.K. and McDonald, H., 2010. A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. Journal of midwifery & women’s health, 55(4), pp.319-327.

Chalmers B, Kaczorowski J, Darling E, Heaman M, Fell DB, O’Brien B, and Lee L, for the Maternity Experiences Study Group of the Canadian Perinatal Surveillance System. Cesarean and vaginal birth in Canadian women: a comparison of experiences. Birth 2010; 37:44-49.

Darling, E. Prenatal screening for chlamydia and gonorrhea: an evidence based approach. Canadian Journal of Midwifery Research & Practice. 2009 8(2):6-14.

BIO

Dr. Liz Darling is the assistant dean of midwifery at McMaster University and is an associate professor in the Department of Obstetrics & Gynecology. Her qualifications include an honours BArtsSc (McMaster), a BHSc in midwifery (McMaster), an MSc in health research methodology (McMaster) and a PhD in population health (Ottawa).

She holds a Canadian Institutes of Health Research (CIHR) Early Career Investigator Award in Maternal, Reproductive, Child and Youth Health that supports a mixed methods research program investigating the impact of funding expanded midwifery care models in Ontario. She is committed to building research capacity within the midwifery profession and currently mentors undergraduate and graduate students in a variety of academic programs.

Dr. Darling practiced midwifery in Ottawa and was a part-time faculty member with the midwifery education program at Laurentian University prior to joining McMaster full-time in 2017. She is also an adjunct scientist at ICES-McMaster and holds an associate appointment in the Department of Health Research Methods, Evidence & Impact at McMaster University. She has represented the midwifery profession in clinical and research committees at the provincial and national level, including serving as a member of the Expert Advisory Committee for the Canadian Perinatal Surveillance System.

AWARDS

• Canadian Institutes of Health Research (CIHR) Early Career Investigator Award in Maternal, Reproductive, Child and Youth Health (2019)
• Association of Ontario Midwives’ Excellence in Midwifery Research Award (2019)
• Joseph De Koninck Doctoral Thesis Award (2015)
• CIHR Vanier Canada Graduate Scholarship (2011)

RESEARCH INTERESTS

Her research focuses on maternal-newborn health services. Areas of interest include: midwifery services, health disparities, access to care, health policy and perinatal health surveillance. She has particular expertise in the midwifery data collected in Ontario’s perinatal registry (BORN-Ontario).

PUBLICATIONS

Darling, E.K., Ramsay, T., Manuel, D., Sprague, A.E., Walker, M.C. and Guttmann, A., 2017. Association of universal bilirubin screening with socioeconomic disparities in newborn follow-up. Academic pediatrics, 17(2), pp.135-143.

Bhardwaj K, Locke T, Biringer A, Booth A, Darling EK, Dougan S, Harrison J, Hill S, Johnson A, Makin S, Potter B, Lacaze-Masmonteil T, Little J. Newborn bilirubin screening for preventing severe hyperbilirubinemia and bilirubin encephalopathy: a rapid review. Curr Pediatr Rev. 2017 Jan 10. doi: 10.2174/1573396313666170110144345

Dunn S, Sprague A, Grimshaw J, Graham I, Taljaard M, Fell D, et. al.. A mixed methods evaluation of the maternal-newborn dashboard in Ontario: dashboard attributes, contextual factors, and facilitators and barriers to use: a study protocol. Implementation Science 2016; 11:59. doi: 10.1186/s13012-016-0427-1

Dzakpasu, S., Fahey, J., Kirby, R.S., Tough, S.C., Chalmers, B., Heaman, M.I., Bartholomew, S., Biringer, A., Darling, E.K., Lee, L.S. and McDonald, S.D., 2015. Contribution of prepregnancy body mass index and gestational weight gain to adverse neonatal outcomes: population attributable fractions for Canada. BMC pregnancy and childbirth, 15(1), p.21.

Darling, E.K., Ramsay, T., Sprague, A.E., Walker, M.C. and Guttmann, A., 2014. Universal bilirubin screening and health care utilization. Pediatrics, 134(4), pp.e1017-e1024.

Dzakpasu, S., Fahey, J., Kirby, R.S., Tough, S.C., Chalmers, B., Heaman, M.I., Bartholomew, S., Biringer, A., Darling, E.K., Lee, L.S. and McDonald, S.D., 2014. Contribution of prepregnancy body mass index and gestational weight gain to caesarean birth in Canada. BMC pregnancy and childbirth, 14(1), p.106.

Darling, E.K., Guttmann, A., Sprague, A.E., Ramsay, T. and Walker, M.C., 2014. La mise en œuvre des lignes directrices sur l’hyperbilirubinémie de la Société canadienne de pédiatrie: une enquête dans les hôpitaux de l’Ontario. Paediatrics & Child Health, 19(3), pp.133-137.

Darling, E.K., Guttmann, A., Sprague, A.E., Ramsay, T. and Walker, M.C., 2014. Implementation of the Canadian Paediatric Society’s hyperbilirubinemia guidelines: a survey of Ontario hospitals. Paediatrics & child health, 19(3), p.133.

Darling, E.K., 2011. Peer Reviewed Article: Vaginal Birth After Cesarean Section: Outcomes of Women Receiving Midwifery Care in Ontario. Canadian Journal of Midwifery Research & Practice, 10(1), p.9.

Darling, E.K., 2011. Is mandatory neonatal eye prophylaxis ethically justified? a case study from Canada. Public Health Ethics, p.phr016.

O’Brien, B., Chalmers, B., Fell, D., Heaman, M., Darling, E.K. and Herbert, P., 2011. The experience of pregnancy and birth with midwives: results from the Canadian maternity experiences survey. Birth, 38(3), pp.207-215.

Darling E. Vaginal birth after cesarean section: Outcomes of women receiving midwifery care in Ontario. Canadian Journal of Midwifery Research and Practice. 2011; 10(1):9-19.

Darling, E.K., 2011. L’accouchement vaginal après une césarienne: les issues des femmes recevant les soins de sages-femmes en Ontario. Canadian Journal of Midwifery Research & Practice, 10(1), p.20.

Darling, E.K. and McDonald, H., 2010. A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. Journal of midwifery & women’s health, 55(4), pp.319-327.

Chalmers B, Kaczorowski J, Darling E, Heaman M, Fell DB, O’Brien B, and Lee L, for the Maternity Experiences Study Group of the Canadian Perinatal Surveillance System. Cesarean and vaginal birth in Canadian women: a comparison of experiences. Birth 2010; 37:44-49.

Darling, E. Prenatal screening for chlamydia and gonorrhea: an evidence based approach. Canadian Journal of Midwifery Research & Practice. 2009 8(2):6-14.

BIO

Dr. Bryon De France is an associate professor in the Department of Obstetrics & Gynecology at McMaster University and a member of the active staff in the clinical department of obstetrics and gynecology at Hamilton Health Sciences Corporation in Hamilton Ontario. He is also an associate member of the Department of Diagnostic Imaging at McMaster University.  Dr. De France is one of the two lead maternal fetal medicine physicians leading the McMaster Diabetes in pregnancy program at McMaster University.

He received his MD at McMaster University and continued there to complete his residency in obstetrics and gynecology. He was the first fellow in the maternal fetal medicine program at McMaster. Prior to his medical education, he completed BSc and MSc degrees in the field of toxicology at the University of Guelph. Dr. De France joined the division of maternal fetal medicine at McMaster in 2001, and has been an active full-time member since that time. He has pursued additional training in clinical epidemiology while on staff at McMaster University and is currently involved in clinical, educational and research activities.

CLINICAL INTERESTS

• Maternal and fetal medicine
• Prenatal diagnosis
• Fetal ultrasound

RESEARCH INTERESTS

Research Themes

Fetal growth; Fetal body composition; Diabetes in pregnancy; Clinical trials

Clinical Trials:

Folic Acid Clinical Trial (FACT) – Local Qualified Investigator
International, Multi-Centered, RCT
The hypothesis of the study is: high dose (4.0 mg per day) supplementation for pregnant women at high risk of developing preeclampsia starting in early pregnancy and continued throughout the entire pregnancy will lower the incidence of preeclampsia.

The trial completed recruitment in November 2015 and the local contribution to recruitment of 161 participants to the final goal of 2464 was 2nd of 72 centers worldwide.

Ongoing Collaborative Work

Dr. Christoph Fusch
Dual closed-loop ex-vivo placenta perfusion

Dr. Christoph Fusch, Dr. Nina Stein, Dr. Mike Noseworthy
Fetal Body Composition

PUBLICATIONS

Malinowski, A. K., De France, B., Sun, D., Carvalho, J. C. A., & Shehata, N. (2017). Obstetric neuraxial anaesthesia in the context of maternal immune thrombocytopenia: secondary analysis of a retrospective cohort study. BJA: British Journal of Anaesthesia, 119(5), 1067-1068.?

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.

Sun, D., Shehata, N., Xiang, Y.Y., Gregorovich, S., De France, B., Arnold, D.M., Shah, P.S. and Malinowski, A.K., 2016. Corticosteroids compared to intravenous immune globulin for the treatment of immune thrombocytopenia in pregnancy. Blood, pp.blood-2016.

Vasanthan, T., Rochow, N., Mian, F., Codini, T., DeFrance, B., Fusch, G., Samiee-Zafarghandy, S. and Fusch, C., 2014. LPS from bovine serum albumin drives TNF-? release during ex-vivo placenta perfusion experiments, contaminates the perfusion system but can be effectively removed by oxidative cleaning. Placenta, 35(12), pp.1095-1098.

Vasanthan, T., Rochow, N., Mian, M.F., DeFrance, B., Fusch, G. and Fusch, C., 2014. Dual closed-loop ex-vivo placental perfusion model: Evidence for relevant LPS contamination and development of a procedure for depyrogenation. Placenta, 35(9), p.A23.

Morais M., Deniz S., Ellis S., DeFrance B., 2011.  Characteristics That Influence the Uptake of Prenatal screening of women delivering in a Canadian urban centre. Journal of Obstetrics and Gynaecology Canada, 33(6) Supplement 1:S37-38.

De France BF. The ALARM and MORE OB Programs – Letter to the Editor. J Obstet Gynaecol Can 2007;29(3):215-217.

DeFrance, B, Brennan, B. “Single Versus Multiple Courses of Antenatal Corticosteroids”. Evidence Based Obstetrics and Gynecology, Vol. 3 (2) Pg. 109-110, June 2001.

RECENT RESIDENT RESEARCH

2015
Sandra Gregorovich
“Corticosteroids Compared to Intravenous Immune Globulin for the Treatment of Immune Thrombocytopenia in Pregnancy”

2014
Esther Chin
“Necrotizing Fasciitis in Obstetrics and Gynecology – a systematic review”

Elissa Tepperman – R.T. Weaver Best Research Recipient
Redefining Hadlock Curves for the Diabetic Population

Karen MacMillan
Relative fetal acidemia in pregestational diabetics compared to non-diabetic controls.

2013
Meredith Giffin – R.T. Weaver Best Research Recipient
“Estimating Fetal Birth Weight in Pregestational Diabetics Using the Gestation-Adjusted Projection Method: Accuracy and Optimal Timing of Estimation

2012
Kersti Ranken – R.T. Weaver Best Research Recipient
Estimation of Fetal Weight in Pregestational Diabetics: A Comparison of 15 Formulas

BIO

Dr. Bryon De France is an associate professor in the Department of Obstetrics & Gynecology at McMaster University and a member of the active staff in the clinical department of obstetrics and gynecology at Hamilton Health Sciences Corporation in Hamilton Ontario. He is also an associate member of the Department of Diagnostic Imaging at McMaster University.  Dr. De France is one of the two lead maternal fetal medicine physicians leading the McMaster Diabetes in pregnancy program at McMaster University.

He received his MD at McMaster University and continued there to complete his residency in obstetrics and gynecology. He was the first fellow in the maternal fetal medicine program at McMaster. Prior to his medical education, he completed BSc and MSc degrees in the field of toxicology at the University of Guelph. Dr. De France joined the division of maternal fetal medicine at McMaster in 2001, and has been an active full-time member since that time. He has pursued additional training in clinical epidemiology while on staff at McMaster University and is currently involved in clinical, educational and research activities.

CLINICAL INTERESTS

• Maternal and fetal medicine
• Prenatal diagnosis
• Fetal ultrasound

RESEARCH INTERESTS

Research Themes

Fetal growth; Fetal body composition; Diabetes in pregnancy; Clinical trials

Clinical Trials:

Folic Acid Clinical Trial (FACT) – Local Qualified Investigator
International, Multi-Centered, RCT
The hypothesis of the study is: high dose (4.0 mg per day) supplementation for pregnant women at high risk of developing preeclampsia starting in early pregnancy and continued throughout the entire pregnancy will lower the incidence of preeclampsia.

The trial completed recruitment in November 2015 and the local contribution to recruitment of 161 participants to the final goal of 2464 was 2nd of 72 centers worldwide.

Ongoing Collaborative Work

Dr. Christoph Fusch
Dual closed-loop ex-vivo placenta perfusion

Dr. Christoph Fusch, Dr. Nina Stein, Dr. Mike Noseworthy
Fetal Body Composition

PUBLICATIONS

Malinowski, A. K., De France, B., Sun, D., Carvalho, J. C. A., & Shehata, N. (2017). Obstetric neuraxial anaesthesia in the context of maternal immune thrombocytopenia: secondary analysis of a retrospective cohort study. BJA: British Journal of Anaesthesia, 119(5), 1067-1068.?

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.

Sun, D., Shehata, N., Xiang, Y.Y., Gregorovich, S., De France, B., Arnold, D.M., Shah, P.S. and Malinowski, A.K., 2016. Corticosteroids compared to intravenous immune globulin for the treatment of immune thrombocytopenia in pregnancy. Blood, pp.blood-2016.

Vasanthan, T., Rochow, N., Mian, F., Codini, T., DeFrance, B., Fusch, G., Samiee-Zafarghandy, S. and Fusch, C., 2014. LPS from bovine serum albumin drives TNF-? release during ex-vivo placenta perfusion experiments, contaminates the perfusion system but can be effectively removed by oxidative cleaning. Placenta, 35(12), pp.1095-1098.

Vasanthan, T., Rochow, N., Mian, M.F., DeFrance, B., Fusch, G. and Fusch, C., 2014. Dual closed-loop ex-vivo placental perfusion model: Evidence for relevant LPS contamination and development of a procedure for depyrogenation. Placenta, 35(9), p.A23.

Morais M., Deniz S., Ellis S., DeFrance B., 2011.  Characteristics That Influence the Uptake of Prenatal screening of women delivering in a Canadian urban centre. Journal of Obstetrics and Gynaecology Canada, 33(6) Supplement 1:S37-38.

De France BF. The ALARM and MORE OB Programs – Letter to the Editor. J Obstet Gynaecol Can 2007;29(3):215-217.

DeFrance, B, Brennan, B. “Single Versus Multiple Courses of Antenatal Corticosteroids”. Evidence Based Obstetrics and Gynecology, Vol. 3 (2) Pg. 109-110, June 2001.

RECENT RESIDENT RESEARCH

2015
Sandra Gregorovich
“Corticosteroids Compared to Intravenous Immune Globulin for the Treatment of Immune Thrombocytopenia in Pregnancy”

2014
Esther Chin
“Necrotizing Fasciitis in Obstetrics and Gynecology – a systematic review”

Elissa Tepperman – R.T. Weaver Best Research Recipient
Redefining Hadlock Curves for the Diabetic Population

Karen MacMillan
Relative fetal acidemia in pregestational diabetics compared to non-diabetic controls.

2013
Meredith Giffin – R.T. Weaver Best Research Recipient
“Estimating Fetal Birth Weight in Pregestational Diabetics Using the Gestation-Adjusted Projection Method: Accuracy and Optimal Timing of Estimation

2012
Kersti Ranken – R.T. Weaver Best Research Recipient
Estimation of Fetal Weight in Pregestational Diabetics: A Comparison of 15 Formulas

BIO

Dr. Christine DeJong is chief of obstetrics and gynecology at Joseph Brant Hospital and associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University.

In addition to obstetrics, Dr. DeJong has an interest in urogynecology and colposcopy.

After earning her BSc from Calvin College in 1987, Dr. DeJong attended graduate school at the University of Guelph, earning her MSc in 1989. In 1992, she graduated from McMaster University Medical School and entered a residency in obstetrics and gynecology.

BIO

Dr. Christine DeJong is chief of obstetrics and gynecology at Joseph Brant Hospital and associate clinical professor in the Department of Obstetrics & Gynecology at McMaster University.

In addition to obstetrics, Dr. DeJong has an interest in urogynecology and colposcopy.

After earning her BSc from Calvin College in 1987, Dr. DeJong attended graduate school at the University of Guelph, earning her MSc in 1989. In 1992, she graduated from McMaster University Medical School and entered a residency in obstetrics and gynecology.

BIO

Dr. Stacy Deniz is a specialist in reproductive endocrinology and infertility. She obtained her specialty training in obstetrics and gynecology at McMaster University in 2012. She completed her two-year subspecialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University and joined the team at ONE Fertility. Dr. Deniz is a fellow of the Royal College of Physicians and Surgeons of Canada and an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University.

Her practice involves the management of patients with female and male factor infertility, polycystic ovarian syndrome, recurrent pregnancy loss, premature ovarian failure and endocrinologic disorders affecting the female reproductive system. Her research interests include the disposition of unused embryos following and in vitro fertilization (IVF) treatment cycle, as well as evaluating and improving the emotional support available to patients’ struggling with fertility issues. Dr. Deniz has advanced training in reproductive surgery including operative laparoscopy and hysteroscopy for fertility management. Most importantly, she is passionate about supporting couples and individuals along their fertility journey while helping them achieve their goal of parenthood.

RESEARCH INTERESTS

Embryo disposition; Mental health and fertility; Patient education and Information delivery; Psychosocial support through fertility treatments

PUBLICATIONS

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Ray, J. G., Deniz, S., Olivieri, A., Pollex, E., Vermeulen, M. J., Alexander, K. S.,… & Hamielec, C. M. (2003). Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel. BMC cardiovascular disorders, 3(1), 3.

BIO

Dr. Stacy Deniz is a specialist in reproductive endocrinology and infertility. She obtained her specialty training in obstetrics and gynecology at McMaster University in 2012. She completed her two-year subspecialty fellowship in gynecologic reproductive endocrinology and infertility at McMaster University and joined the team at ONE Fertility. Dr. Deniz is a fellow of the Royal College of Physicians and Surgeons of Canada and an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University.

Her practice involves the management of patients with female and male factor infertility, polycystic ovarian syndrome, recurrent pregnancy loss, premature ovarian failure and endocrinologic disorders affecting the female reproductive system. Her research interests include the disposition of unused embryos following and in vitro fertilization (IVF) treatment cycle, as well as evaluating and improving the emotional support available to patients’ struggling with fertility issues. Dr. Deniz has advanced training in reproductive surgery including operative laparoscopy and hysteroscopy for fertility management. Most importantly, she is passionate about supporting couples and individuals along their fertility journey while helping them achieve their goal of parenthood.

RESEARCH INTERESTS

Embryo disposition; Mental health and fertility; Patient education and Information delivery; Psychosocial support through fertility treatments

PUBLICATIONS

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Ray, J. G., Deniz, S., Olivieri, A., Pollex, E., Vermeulen, M. J., Alexander, K. S.,… & Hamielec, C. M. (2003). Increased blood product use among coronary artery bypass patients prescribed preoperative aspirin and clopidogrel. BMC cardiovascular disorders, 3(1), 3.

BIO

Dr. Cara Donnery completed her bachelor of arts and science at McMaster University in 2000. She then went on to complete her medical degree in 2003 and residency in obstetrics and gynecology in 2008 at McMaster.  A self-described “McMaster Lifer”, she was thrilled to join the department as a clinical scholar in 2008, before accepting a full-time academic position with the department in 2009. During her clinical scholar year, she focused on medical education completing both the basic and advanced clinical teaching certificates through the program for faculty development. She has also completed the faculty of health sciences academic leadership program. Dr. Donnery’s passion for mentoring and teaching has earned her several teaching awards including the CREOG Teaching Award for excellence in resident teaching and the APOG Carl Nimrod award. Her clinical practice is based out of St. Joseph’s Healthcare and focuses on general obstetrics, gynecology and colposcopy.

PUBLICATIONS

Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, S., 2017. P-OBS-JM-061 Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery: A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, E. (2017). Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

Sharpe, C.J., Crowther, M.A., Webert, K.E. and Donnery, C., 2011. Cerebral venous thrombosis during pregnancy in the setting of type I antithrombin deficiency: case report and literature review. Transfusion medicine reviews, 25(1), pp.61-65.

BIO

Dr. Cara Donnery completed her bachelor of arts and science at McMaster University in 2000. She then went on to complete her medical degree in 2003 and residency in obstetrics and gynecology in 2008 at McMaster.  A self-described “McMaster Lifer”, she was thrilled to join the department as a clinical scholar in 2008, before accepting a full-time academic position with the department in 2009. During her clinical scholar year, she focused on medical education completing both the basic and advanced clinical teaching certificates through the program for faculty development. She has also completed the faculty of health sciences academic leadership program. Dr. Donnery’s passion for mentoring and teaching has earned her several teaching awards including the CREOG Teaching Award for excellence in resident teaching and the APOG Carl Nimrod award. Her clinical practice is based out of St. Joseph’s Healthcare and focuses on general obstetrics, gynecology and colposcopy.

PUBLICATIONS

Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, S., 2017. P-OBS-JM-061 Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery: A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, E. (2017). Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

Sharpe, C.J., Crowther, M.A., Webert, K.E. and Donnery, C., 2011. Cerebral venous thrombosis during pregnancy in the setting of type I antithrombin deficiency: case report and literature review. Transfusion medicine reviews, 25(1), pp.61-65.

BIO

Dr. Marie-Josée Dubé was born in Québec City and moved to Montréal to obtain her cégep diploma at the renowned Collège Jean-de-Brébeuf. She then completed an undergraduate bachelor’s degree in political science and studied public administration (health policies) at the graduate level, both at Laval University in Québec.

After having obtained her dedical doctorate at Laval University, she completed her post-graduate residency training in obstetrics and gynecology at McMaster University in Hamilton, Ontario, in 2004. During her medical and gynecological training, she worked in Paris (France) and in Sousse (Tunisia- SOGC Fellowship and Berlex Grant). She is a fellow of the Royal College of Physicians and Surgeons of Canada.

Dr. Dubé did a fellowship in minimally invasive surgery at the Hôpitaux Universitaires de Genève, in Switzerland (2005). She has been an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University since 2006.

Her recent work interests revolve around colposcopy, advanced laparoscopic surgeries, hysteroscopy and family planning. Dr. Dubé had a special interest in teaching minimally invasive surgical techniques to the residents of the program and to gynecologists in and around the Hamilton region. She was actively involved in the Centre for Minimal Access Surgery (CMAS) sessions for junior and senior residents.

AWARDS

• Outstanding Resident Teacher Award – 2004
• H. R. Morgan Surgical Teaching Award – 2007

PUBLICATIONS, LECTURES, VIDEO AND SCIENTIFIC MEETINGS:

1. Traitement conservateur des fibromes : recommandations pour la pratique
   JB Dubuisson, MJ Dubé, D Stucki PD Hagmann, T Hess, HM Hoogewoud, S Jacob, K Kinkel, MD Mueller, S Sporri, R Steiner, JM Wenger.
   Revue Médicale Suisse, novembre 2005, no 40, pp.2591-2597.
2. Laparoscopic Treatment of Genital Prolapse: results of a series on 42 cases of Lateral Suspension using a Mesh.
   JB Dubuisson, S Jacob, JM Wenger, MJ Dubé
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S72.
3. Towards a Swiss Consensus on Laparoscopic Hysterectomy
   MJ Dubé, JB Dubuisson
   SwissendosFribourg, Advanced Laparoscopic Courses, Fribourg, April 2005, Oral Presentation (by JB Dubuisson)
4. Laparoscopic Myomectomy with Uterine Artery Ligation.
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   Oral presentation (by JB Dubuisson) at the ASRM International Meeting, Montréal, October 2005
5. Laparoscopic Anterolateral Colposuspension for the Treatment of Stress Urinary Incontinence and Lateral Cystocele.
   Video, May 2005
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   AAGL Annual Meeting, Chicago, Nov. 2005
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S118.
6. Laparoscopic Myomectomy.
   Video, April 2005
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   AAGL Annual Meeting, Chicago, Nov. 2005
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S118.
7. New Laparoscopic Technique for Cure of Cystocele and Stress Urinary Incontinence Without Mesh.
   Video, November 2006
   JB Dubuisson, MJ Dubé, S Jacob, AT Vlastos, M Ghahremani
   AAGL 35th Global Congress, Las Vegas, November 2006
   The Journal of Minimally Invasive Gynecology, September/October 2006, vol 13, no 5, Supplement, p.S161

BIO

Dr. Marie-Josée Dubé was born in Québec City and moved to Montréal to obtain her cégep diploma at the renowned Collège Jean-de-Brébeuf. She then completed an undergraduate bachelor’s degree in political science and studied public administration (health policies) at the graduate level, both at Laval University in Québec.

After having obtained her dedical doctorate at Laval University, she completed her post-graduate residency training in obstetrics and gynecology at McMaster University in Hamilton, Ontario, in 2004. During her medical and gynecological training, she worked in Paris (France) and in Sousse (Tunisia- SOGC Fellowship and Berlex Grant). She is a fellow of the Royal College of Physicians and Surgeons of Canada.

Dr. Dubé did a fellowship in minimally invasive surgery at the Hôpitaux Universitaires de Genève, in Switzerland (2005). She has been an assistant clinical professor in the Department of Obstetrics & Gynecology at McMaster University since 2006.

Her recent work interests revolve around colposcopy, advanced laparoscopic surgeries, hysteroscopy and family planning. Dr. Dubé had a special interest in teaching minimally invasive surgical techniques to the residents of the program and to gynecologists in and around the Hamilton region. She was actively involved in the Centre for Minimal Access Surgery (CMAS) sessions for junior and senior residents.

AWARDS

• Outstanding Resident Teacher Award – 2004
• H. R. Morgan Surgical Teaching Award – 2007

PUBLICATIONS, LECTURES, VIDEO AND SCIENTIFIC MEETINGS:

1. Traitement conservateur des fibromes : recommandations pour la pratique
   JB Dubuisson, MJ Dubé, D Stucki PD Hagmann, T Hess, HM Hoogewoud, S Jacob, K Kinkel, MD Mueller, S Sporri, R Steiner, JM Wenger.
   Revue Médicale Suisse, novembre 2005, no 40, pp.2591-2597.
2. Laparoscopic Treatment of Genital Prolapse: results of a series on 42 cases of Lateral Suspension using a Mesh.
   JB Dubuisson, S Jacob, JM Wenger, MJ Dubé
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S72.
3. Towards a Swiss Consensus on Laparoscopic Hysterectomy
   MJ Dubé, JB Dubuisson
   SwissendosFribourg, Advanced Laparoscopic Courses, Fribourg, April 2005, Oral Presentation (by JB Dubuisson)
4. Laparoscopic Myomectomy with Uterine Artery Ligation.
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   Oral presentation (by JB Dubuisson) at the ASRM International Meeting, Montréal, October 2005
5. Laparoscopic Anterolateral Colposuspension for the Treatment of Stress Urinary Incontinence and Lateral Cystocele.
   Video, May 2005
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   AAGL Annual Meeting, Chicago, Nov. 2005
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S118.
6. Laparoscopic Myomectomy.
   Video, April 2005
   JB Dubuisson, MJ Dubé, S Jacob, JM Wenger
   AAGL Annual Meeting, Chicago, Nov. 2005
   The Journal of Minimally Invasive Gynecology, September/October 2005, vol 12, no 5, Supplement, p.S118.
7. New Laparoscopic Technique for Cure of Cystocele and Stress Urinary Incontinence Without Mesh.
   Video, November 2006
   JB Dubuisson, MJ Dubé, S Jacob, AT Vlastos, M Ghahremani
   AAGL 35th Global Congress, Las Vegas, November 2006
   The Journal of Minimally Invasive Gynecology, September/October 2006, vol 13, no 5, Supplement, p.S161

BIO

Lua R. Eiriksson completed her medical degree at Dalhousie University and residency in obstetrics and gynecology at the University of Alberta. She completed a three-year fellowship in gynecologic oncology at the University of Toronto (Princess Margaret Cancer Centre and Odette/Sunnybrook Cancer Centre), and obtained a masters in public health in epidemiology from the University of Toronto’s Dalla Lana School of Public Health. She has been a gynecologic oncologist at the Juravinski Cancer Centre and an assistant professor in the Department of Obstetrics & Gynecology at McMaster University since 2013.

RESEARCH INTERESTS

Current research interests include cervical cancer prevention and health advocacy, universal screening for Lynch Syndrome in patients with endometrial and epithelial ovarian cancer, the use of risk of malignancy scoring in patients with suspected ovarian cancer, occupational exposures and ovarian cancer risk, quality indicators in clinical practice and centre-specific patient outcomes by disease site and treatment received. She is involved with the MD program as a student advisor, tutor, lecturer, mentor for simulation training and clinical mentor. She is also involved with the obstetrics and gynecology program as an ombudsmen, a member of the Obstetrics & Gynecology Surgical Curriculum Committee, Objective Structured Clinical Examination (OSCE) supervisor, lecturer, clinical mentor and research project supervisor. She is also a member of the New Patient Referral Project Quality Improvement Working Group at the Juravinski Cancer Centre.

PUBLICATIONS

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Elit, L. and Kong, I., 2016. Outcomes of Stage IA Serous Endometrial Adenocarcinoma. Brachytherapy, 15, pp.S111-S112.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Pond, G., Memon, S., Elit, L. and Kong, I., 2016. 228: Pathologic and Treatment Factors Associated with Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. Radiotherapy and Oncology, 120, p.S83.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Pond, G., Elit, L. and Kong, I., 2016. The Pathologic and Treatment Factors Associated With Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. International Journal of Radiation Oncology• Biology• Physics, 96(2), p.E315.

Eiriksson, L., Aronson, M., Clarke, B., Mojtahedi, G., Massey, C., Oza, A.M., Gallinger, S., Pollett, A., Mackay, H., Bernardini, M.Q. and Ferguson, S.E., 2015. Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer. Gynecologic oncology, 136(2), pp.311-316.

Lennox, G.K., Eiriksson, L.R., Reade, C.J., Leung, F., Mojtahedi, G., Atenafu, E.G., Ferguson, S.E., Murphy, J., Diamandis, E.P., Kulasingam, V. and Bernardini, M.Q., 2015. Effectiveness of the risk of malignancy index and the risk of ovarian malignancy algorithm in a cohort of women with ovarian cancer: does histotype and stage matter?. International Journal of Gynecological Cancer, 25(5), pp.809-814.

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS?0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Eiriksson, L.R., Millar, H.C., Lennox, G.K., Reade, C.J.M., Leung, F., Diamandis, E.P., Kulasingam, V., Murphy, K.J., Ferguson, S.E. and Bernardini, M.Q., 2014. The usefulness of ovarian cancer risk scoring in the discrimination of an isolated pelvic mass. Gynecologic Oncology, 133, pp.82-83.

Reade, C.J., Eiriksson, L.R. and Mackay, H., 2014. Systemic therapy in squamous cell carcinoma of the vulva: current status and future directions. Gynecologic oncology, 132(3), pp.780-789.

Reade, C.J.M., Habiba, U., Eiriksson, L.R., Cesari, M. and Osborne, R.J., 2014. Treatment of low-risk GTN with biweekly actinomycin-D. Gynecologic Oncology, 133, pp.185-186.

Ferguson, S.E., Aronson, M., Pollett, A., Eiriksson, L.R., Oza, A.M., Gallinger, S., Lerner?Ellis, J., Alvandi, Z., Bernardini, M.Q., MacKay, H.J. and Mojtahedi, G., 2014. Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing. Cancer, 120(24), pp.3932-3939.

Eiriksson, L. and Covens, A., 2012. Advancing fertility-sparing treatments in cervical cancer: Where is the limit?. Gynecologic Oncology, 126, pp.317-8.

Eiriksson, L., Kaur, H., Ismiil, N., Barbera, L. and Covens, A., 2013. The significance of primary tumor factors and treatment received in risk of recurrence in clinical stage I high-grade endometrial adenocarcinoma. Gynecologic Oncology, 130(1), p.e72.

Ferguson, S.E., Aronson, M., Eiriksson, L.R., Mojtahedi, G., Pollett, A., Gallinger, S., Oza, A.M., Mackay, H., Bernardini, M., Lerner-Ellis, J. and Clarke, B., 2013. Screening for Lynch syndrome in unselected women with endometrial cancer.  Journal of Clinical Oncology, 31(15 suppl), pp. 5508-5508.

Eiriksson, L., Harris, M., Hardt, J., Tjepkema, M., Peters, P. and Demers, P., 2013. Occupational exposures and ovarian cancer: A national population-based cohort study. Gynecologic Oncology, 130(1), pp.e142-e143.

Reade, C., Osborne, R., Shah, N., Eiriksson, L., Dodge, J., Moens, F. and Goeree, R., 2013. Treatment of low-risk gestational trophoblastic neoplasia: A probabilistic decision analysis model. Gynecologic Oncology, 130(1), pp.e27-e28.

Reade, C.J., Eiriksson, L.R. and Covens, A., 2013. Surgery for early stage cervical cancer: how radical should it be?. Gynecologic oncology, 131(1), pp.222-230.

Eiriksson, L.R., Reade, C.J., Lennox, G., Mojtahedi, G., Murphy, J., Ferguson, S.E. and Bernardini, M.Q., 2013. Ovarian cancer distribution of histology, stage, and screening performance. Journal of Clinical Oncology, 31, p.5543.

Eiriksson, L., Reade, C.J. and Elit, L., 2013. Meeting highlights: International Gynecologic Cancer Society (IGCS 2012). Gynecologic oncology, 128(1), pp.12-14.

Eiriksson, L., Wells, T., Steed, H., Schepansky, A., Capstick, V., Hoskins, P., Pike, J. and Swenerton, K., 2012. Combined methotrexate–dactinomycin: An effective therapy for low-risk gestational trophoblastic neoplasia. Gynecologic oncology, 124(3), pp.553-557.

Kaur, H., Eiriksson, L., Saad, R., Khalifa, M., Dube, V., Ghorab, Z., Covens, A., Barbera, L. and Ismiil, N., 2012, February. Prognostic Significance of Primary Tumour Factors in Stage III High Grade Endometrial Cancer. Laboratory Investigation, 92, pp. 280A-280A).

Eiriksson, L.R. and Covens, A., 2012. Sentinel lymph node mapping in cervical cancer: the future?. BJOG: An International Journal of Obstetrics & Gynaecology, 119(2), pp.129-133.

J Reade, C., R Eiriksson, L. and Covens, A., 2012. A review of surgical options to preserve fertility in the treatment of early cervical cancer. Current Women’s Health Reviews, 8(3), pp.219-230.

Eiriksson LR, Covens A. Follow-up after chemoradiation for cervical cancer: Why? Cancer. 2011;117(17):3875-8.

Eiriksson L, Covens A. Fertility-Sparing Surgery in Cervical Cancer. European Obstetrics & Gynaecology.  2011;6(1):52-5.

Eiriksson L, Cuartero J, Steed H, Pearcey R, Capstick V, Schepansky A, Faught W, Dundas G. Assessment of outcomes in surgically staged I/II endometrial adenocarcinoma patients treated with postoperative vaginal vault radiotherapy only. International Journal of Gynecologic Cancer. 2010 Nov;20(8):1356-62.

Eiriksson L, Covens A. Conservative surgery for early stage cervical cancer: who should we offer it to? Gynecology Oncology. 2010;119(2)173-4.

BIO

Lua R. Eiriksson completed her medical degree at Dalhousie University and residency in obstetrics and gynecology at the University of Alberta. She completed a three-year fellowship in gynecologic oncology at the University of Toronto (Princess Margaret Cancer Centre and Odette/Sunnybrook Cancer Centre), and obtained a masters in public health in epidemiology from the University of Toronto’s Dalla Lana School of Public Health. She has been a gynecologic oncologist at the Juravinski Cancer Centre and an assistant professor in the Department of Obstetrics & Gynecology at McMaster University since 2013.

RESEARCH INTERESTS

Current research interests include cervical cancer prevention and health advocacy, universal screening for Lynch Syndrome in patients with endometrial and epithelial ovarian cancer, the use of risk of malignancy scoring in patients with suspected ovarian cancer, occupational exposures and ovarian cancer risk, quality indicators in clinical practice and centre-specific patient outcomes by disease site and treatment received. She is involved with the MD program as a student advisor, tutor, lecturer, mentor for simulation training and clinical mentor. She is also involved with the obstetrics and gynecology program as an ombudsmen, a member of the Obstetrics & Gynecology Surgical Curriculum Committee, Objective Structured Clinical Examination (OSCE) supervisor, lecturer, clinical mentor and research project supervisor. She is also a member of the New Patient Referral Project Quality Improvement Working Group at the Juravinski Cancer Centre.

PUBLICATIONS

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Elit, L. and Kong, I., 2016. Outcomes of Stage IA Serous Endometrial Adenocarcinoma. Brachytherapy, 15, pp.S111-S112.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Pond, G., Memon, S., Elit, L. and Kong, I., 2016. 228: Pathologic and Treatment Factors Associated with Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. Radiotherapy and Oncology, 120, p.S83.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Pond, G., Elit, L. and Kong, I., 2016. The Pathologic and Treatment Factors Associated With Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. International Journal of Radiation Oncology• Biology• Physics, 96(2), p.E315.

Eiriksson, L., Aronson, M., Clarke, B., Mojtahedi, G., Massey, C., Oza, A.M., Gallinger, S., Pollett, A., Mackay, H., Bernardini, M.Q. and Ferguson, S.E., 2015. Performance characteristics of a brief Family History Questionnaire to screen for Lynch syndrome in women with newly diagnosed endometrial cancer. Gynecologic oncology, 136(2), pp.311-316.

Lennox, G.K., Eiriksson, L.R., Reade, C.J., Leung, F., Mojtahedi, G., Atenafu, E.G., Ferguson, S.E., Murphy, J., Diamandis, E.P., Kulasingam, V. and Bernardini, M.Q., 2015. Effectiveness of the risk of malignancy index and the risk of ovarian malignancy algorithm in a cohort of women with ovarian cancer: does histotype and stage matter?. International Journal of Gynecological Cancer, 25(5), pp.809-814.

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS?0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Eiriksson, L.R., Millar, H.C., Lennox, G.K., Reade, C.J.M., Leung, F., Diamandis, E.P., Kulasingam, V., Murphy, K.J., Ferguson, S.E. and Bernardini, M.Q., 2014. The usefulness of ovarian cancer risk scoring in the discrimination of an isolated pelvic mass. Gynecologic Oncology, 133, pp.82-83.

Reade, C.J., Eiriksson, L.R. and Mackay, H., 2014. Systemic therapy in squamous cell carcinoma of the vulva: current status and future directions. Gynecologic oncology, 132(3), pp.780-789.

Reade, C.J.M., Habiba, U., Eiriksson, L.R., Cesari, M. and Osborne, R.J., 2014. Treatment of low-risk GTN with biweekly actinomycin-D. Gynecologic Oncology, 133, pp.185-186.

Ferguson, S.E., Aronson, M., Pollett, A., Eiriksson, L.R., Oza, A.M., Gallinger, S., Lerner?Ellis, J., Alvandi, Z., Bernardini, M.Q., MacKay, H.J. and Mojtahedi, G., 2014. Performance characteristics of screening strategies for Lynch syndrome in unselected women with newly diagnosed endometrial cancer who have undergone universal germline mutation testing. Cancer, 120(24), pp.3932-3939.

Eiriksson, L. and Covens, A., 2012. Advancing fertility-sparing treatments in cervical cancer: Where is the limit?. Gynecologic Oncology, 126, pp.317-8.

Eiriksson, L., Kaur, H., Ismiil, N., Barbera, L. and Covens, A., 2013. The significance of primary tumor factors and treatment received in risk of recurrence in clinical stage I high-grade endometrial adenocarcinoma. Gynecologic Oncology, 130(1), p.e72.

Ferguson, S.E., Aronson, M., Eiriksson, L.R., Mojtahedi, G., Pollett, A., Gallinger, S., Oza, A.M., Mackay, H., Bernardini, M., Lerner-Ellis, J. and Clarke, B., 2013. Screening for Lynch syndrome in unselected women with endometrial cancer.  Journal of Clinical Oncology, 31(15 suppl), pp. 5508-5508.

Eiriksson, L., Harris, M., Hardt, J., Tjepkema, M., Peters, P. and Demers, P., 2013. Occupational exposures and ovarian cancer: A national population-based cohort study. Gynecologic Oncology, 130(1), pp.e142-e143.

Reade, C., Osborne, R., Shah, N., Eiriksson, L., Dodge, J., Moens, F. and Goeree, R., 2013. Treatment of low-risk gestational trophoblastic neoplasia: A probabilistic decision analysis model. Gynecologic Oncology, 130(1), pp.e27-e28.

Reade, C.J., Eiriksson, L.R. and Covens, A., 2013. Surgery for early stage cervical cancer: how radical should it be?. Gynecologic oncology, 131(1), pp.222-230.

Eiriksson, L.R., Reade, C.J., Lennox, G., Mojtahedi, G., Murphy, J., Ferguson, S.E. and Bernardini, M.Q., 2013. Ovarian cancer distribution of histology, stage, and screening performance. Journal of Clinical Oncology, 31, p.5543.

Eiriksson, L., Reade, C.J. and Elit, L., 2013. Meeting highlights: International Gynecologic Cancer Society (IGCS 2012). Gynecologic oncology, 128(1), pp.12-14.

Eiriksson, L., Wells, T., Steed, H., Schepansky, A., Capstick, V., Hoskins, P., Pike, J. and Swenerton, K., 2012. Combined methotrexate–dactinomycin: An effective therapy for low-risk gestational trophoblastic neoplasia. Gynecologic oncology, 124(3), pp.553-557.

Kaur, H., Eiriksson, L., Saad, R., Khalifa, M., Dube, V., Ghorab, Z., Covens, A., Barbera, L. and Ismiil, N., 2012, February. Prognostic Significance of Primary Tumour Factors in Stage III High Grade Endometrial Cancer. Laboratory Investigation, 92, pp. 280A-280A).

Eiriksson, L.R. and Covens, A., 2012. Sentinel lymph node mapping in cervical cancer: the future?. BJOG: An International Journal of Obstetrics & Gynaecology, 119(2), pp.129-133.

J Reade, C., R Eiriksson, L. and Covens, A., 2012. A review of surgical options to preserve fertility in the treatment of early cervical cancer. Current Women’s Health Reviews, 8(3), pp.219-230.

Eiriksson LR, Covens A. Follow-up after chemoradiation for cervical cancer: Why? Cancer. 2011;117(17):3875-8.

Eiriksson L, Covens A. Fertility-Sparing Surgery in Cervical Cancer. European Obstetrics & Gynaecology.  2011;6(1):52-5.

Eiriksson L, Cuartero J, Steed H, Pearcey R, Capstick V, Schepansky A, Faught W, Dundas G. Assessment of outcomes in surgically staged I/II endometrial adenocarcinoma patients treated with postoperative vaginal vault radiotherapy only. International Journal of Gynecologic Cancer. 2010 Nov;20(8):1356-62.

Eiriksson L, Covens A. Conservative surgery for early stage cervical cancer: who should we offer it to? Gynecology Oncology. 2010;119(2)173-4.

BIO

Laurie Elit MD MSc FRCS (C) is a professor in the Department of Obstetrics & Gynecology at McMaster University and the division head for gynecologic oncology at Hamilton Health Sciences Centre-Juravinski Cancer Centre. She obtained her medical degree at University of Western Ontario, her fellowship in obstetrics and gynecology at University of Western Ontario, and her gynecologic oncology training at Pennsylvania Hospital, Philadelphia and the University of Toronto. She completed a master’s in health research and methodology at McMaster University. Her research interests involve health services delivery for gynecologic cancer in particular ovarian cancer, treatment decision making with a focus in ovarian cancer and clinical trials with a focus in preinvasive disease. She is the gynecologic disease site team lead for Cancer Care Ontario’s Program in Evidence-Based Care. She has volunteered as an educator, clinician and administrator in several low and middle income settings (i.e., Papua New Guinea, Haiti, Bangladesh, Pakistan, Mongolia, Macedonia). Dr. Elit will be increasing her time commitment to global health endeavors working at Mbingo Baptist Hospital, Cameroon beginning January 2021.

AWARDS

• 2020 Mohide Lectureship, McMaster University, Hamilton
• 2019 Ontario Society of Obstetrics and Gynecology life time achievement award
• 2019 Hamilton Health Sciences Centre Medical Staff Award for Community or Global Humanitarianism
• 2019 Dr. John Mazurka Award for Clinical Surgical Teaching
• 2016 Gynecologic Oncology Canada Presidential Medal
• 2016 Hamilton Health Sciences Centre Medical Staff Association President’s Award for Distinguished Long Service
• 2014 Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Gynecologic Surgical Training. Department of Obstetrics & Gynecology.
• 2011 American College of Obstetricians and Gynecologists (CREOG) National Faculty Award for Excellence in Resident Education
• 2007 MacKenzie Fellowship in Surgery, Royal College of Physicians and Surgeons Canada
• 2006 Clinical Traineeship Grant from the Royal College of Physicians and Surgeons Canada

RESEARCH INTERESTS

• Health Services Research in Gynecologic Oncology specifically ovarian cancer.
• Randomized trials specifically in CIN 1, PET Scanning for cervical cancer and ovarian cancer.
• Treatment decision making in ovarian cancer.

Research Themes

Ovarian cancer; Cervical cancer; Quality improvement; Screening; Pre-invasive disease

PUBLICATIONS

Francis JA, Elit L, Coakley N, MacKay H And Gynecologic Cancer Disease Site Group. Systematic therapy for recurrent epithelial ovarian cancer: a clinical practice guideline. Current Oncology. 2017;24(6):e540-e546 doi: 10.3747/co.24.3824

Elit L, Fyles A, Gu C, Pond G, D’Souza D, Samant R, Anthes M, Thomas G, Filion M, Arsenault J, Dayes I, Whelan T, Gulenchyn K, Metser U, Dhamanaskar K, Levine M. Impact of Positron Emission Tomography (PET) imaging in Women with locally advanced cervical cancer: a Randomized trial. JAMA Open Network 2018:1(5):e182081 doi:10.1001/jamanetworkopen.2018.2081 14Sep2018 pp1-13

Shakeel, S., Elit, L., Akhtar-Danesh, N., Schneider, L. and Finley, C., 2017. Care Delivery Patterns, Processes, and Outcomes for Primary Ovarian Cancer Surgery: A Population-Based Review Using a National Administrative  Database. Journal of Obstetrics and Gynaecology Canada, 39(1), pp.25-33.

Barbera, L., Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Fyles, A., Rakovitch, E., Liu, Y. and  Khalifa, M., 2017. The Added Value of Pathology Review in Vulvar Cancer: Results From a Population-based Cohort Study. International Journal of Gynecological Pathology, 36(2), pp.107-110.

McGee, J., Panabaker, K., Leonard, S., Ainsworth, P., Elit, L. and Shariff, S.Z., 2017. Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario. International Journal of Gynecological Cancer, 27(3), pp.437-443.

Serrano Aybar, P.E., Dhamanaskar, K., Elit, L., Parpia, S., Linkins, L.A., Simunovic, M., Ruo, L., Bhandari, M. and Levine, M.N., 2017. Incidence of venous thromboembolic events following major pelvic and abdominal surgery for cancer. Journal of Clinical Oncology, 35(4) Suppl, pp. 478-478.

Elit, L., 2016. Cervical cancer screening in women over 65. PRO: Are we asking the right question?. Gynecologic Oncology, 142(3), pp.381-382.

Bezanson, K., Nouvet, E., Hunt, M., de Laat, S., Elit, L., Bernard, C. and Schwartz, L., 2016. D08-C The Place of Palliative Care in Humanitarian Response. Journal of Pain and Symptom Management, 52(6), pp.e34-e35.

Mackay, H., Soobrian, J., Murphy, J., Elit, L., Milosevic, M.F., Gollnow, A., Ross, J. and Holloway, C., 2016. Pathway map development as an approach to identifying priority areas for quality improvement in Ontario. Journal of Clinical Oncology, 34(7) Suppl pp. 108-108.

Le, T., Kennedy, E.B., Dodge, J. and Elit, L., 2016. Follow-up of patients who are clinically disease-free after primary treatment for fallopian tube, primary peritoneal, or epithelial ovarian cancer: a Program in Evidence-Based Care guideline adaptation. Current Oncology, 23(5), p.343.

Elit, L., Kennedy, E.B., Fyles, A. and Metser, U., 2016. Follow-up for cervical cancer: a Program in Evidence-Based Care systematic review and clinical practice guideline update. Current Oncology, 23(2), p.109.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2016. Challenges in striving to simultaneously achieve multiple resource allocation goals: the pan-Canadian Oncology Drug Review (pCODR) example. Journal of Market  Access & Health Policy, 4.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Pond, G., Elit, L. and Kong, I., 2016. The Pathologic and Treatment Factors Associated With Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. International Journal of Radiation Oncology• Biology• Physics, 96(2), p.E315.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Pond, G., Memon, S., Elit, L. and Kong, I., 2016. 228: Pathologic and Treatment Factors Associated with Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. Radiotherapy and Oncology, 120, p.S83.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Elit, L. and Kong, I., 2016. Outcomes of Stage IA  Serous Endometrial Adenocarcinoma. Brachytherapy, 15, pp.S111-S112.

Voruganti, T., Moineddin, R., Jembere, N., Elit, L., Grunfeld, E. and Lofters, A.K., 2016. Comparing stage of  diagnosis of cervical cancer at presentation in immigrant women and long-term residents of Ontario: a retrospective  cohort study. CMAJ open, 4(3), p.E424.

Elit, L., 2015. Wait times from diagnosis to treatment in cancer. Journal of gynecologic oncology, 26(4),  pp.246-248.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2015. Is there an economic rationale for cancer drugs to  have a separate reimbursement review process for resource allocation purposes?. Pharmacoeconomics, 33(3), pp.235-241.

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS-0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Fung-Kee-Fung, M., Kennedy, E.B., Biagi, J., Colgan, T., D’Souza, D., Elit, L.M., Hunter, A., Irish, J.,  McLeod, R. and Rosen, B., 2015. The optimal organization of gynecologic oncology services: a systematic review. Current Oncology, 22(4), p.e282.

Elit L, Pond G, Seow H. Letter to the Editor. Wait Time and Survival for Type 1 Endometrial Cancer. Obstetrics and Gynecology 2015:125(6):

Kroft, J., Li, Q., Saskin, R., Elit, L., Bernardini, M.Q. and Gien, L.T., 2015. Trends over time in the use of laparoscopic hysterectomy for the treatment of endometrial cancer. Gynecologic oncology, 138(3), pp.536-541.

Elit, L.M., Pond, G. and Seow, H., 2015. Time interval between endometrial biopsy and surgical staging for  type I endometrial cancer: association between tumor characteristics and survival outcome. Obstetrics &  Gynecology, 125(6), pp.1497-1498.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2015. The Silence in Hoch et al.’s Commentary about the  Rationale for and Objective (s) of Canada’s Separate HTA Process for Cancer Drugs: The Importance of Transparency and Accountability when Allocating Taxpayers’ Dollars. PharmacoEconomics, 33(8), pp.883-886.

Elit, L.M., Fyles, A.W., Gu, C.S., Pond, G.R., D’Souza, D., Samant, R., Anthes, M., Thomas, G., Fillion, M.,  Arsenault, J. and Dayes, I., 2015. The role of PET-CT in treatment decision making for women with locally advanced cervical cancer. Journal of Clinical Oncology, 33(15) Suppl, pp. 5523-5523.

Murphy, J., Varela, N.P., Elit, L., Lytwyn, A., Yudin, M., Shier, M., Wu, V. and El-Khatib, S., 2015. The organization of colposcopy services in Ontario: recommended framework. Current Oncology, 22(4), p.287.

Elit, L., Charles, C.A. and Gafni, A., 2015. Oncologists’ Perceptions of Recurrent Ovarian Cancer Patients’  Preference for Participation in Treatment Decision Making and Strategies for When and How to Involve Patients in This Process. International Journal of Gynecological Cancer, 25(9), pp.1717-1723.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2015. Further Insights Into Long-Term Trends in Relative Survival of Vulvar Cancer Patients: A Population-Based Study. International Journal of Gynecological Cancer, 25(1), pp.125-130.

Fung-Kee-Fung, M., Kennedy, E.B., Biagi, J., Colgan, T., D’Souza, D., Elit, L.M., Hunter, A., Irish, J., McLeod, R. and Rosen, B., 2015. An organizational guideline for gynecologic oncology services. International Journal of Gynecological Cancer, 25(4), pp.551-558.

Elit LM, Charles CA, Gafni A. Oncologists’ perceptions of recurrent ovarian cancer patients’ preference for participation in treatment decision and making and strategies for when and how to involve patients in this process. IJGC, 25(9), 1717-23.

Elit, L. and Reade, C.J., 2015. Recommendations for follow-up care for gynecologic cancer survivors. Obstetrics & Gynecology, 126(6), pp.1207-1214.

Hirte, H., Kennedy, E.B., Elit, L. and Fung, M.F.K., 2015. Systemic therapy for recurrent, persistent, or metastatic cervical cancer: a clinical practice guideline. Current Oncology, 22(3), p.211.

Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Rakovitch, E., Fyles, A., Khalifa, M.A., Liu, Y. and Barbera, L., 2015. Patient, tumor, and health system factors affecting groin node dissection rates in vulvar carcinoma: A population-based cohort study. Gynecologic oncology, 139(3), pp.465-470.

Elit, L. and Reade, C.J., 2015. Recomendaciones para la Atención de Seguimiento a Sobrevivientes de Cáncer Ginecológico. Obstet Gynecol, 126, pp.1207-1214.

Prummel, M.V., Young, S.W., Candido, E., Nishri, D., Elit, L. and Marrett, L.D., 2014. Cervical cancer incidence in ontario women: differing sociodemographic gradients by morphologic type (adenocarcinoma versus squamous cell). International Journal of Gynecological Cancer, 24(7), pp.1341-1346.

Tsoref, D., Welch, S., Lau, S., Biagi, J., Tonkin, K., Martin, L.A., Ellard, S., Ghatage, P., Elit, L., Mackay, H.J. and Allo, G., 2014. Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer. Gynecologic oncology, 135(2), pp.184-189.

Elit, L., and Hirte, H., 2014. Novel Targeted Therapies in Ovarian Cancer. Journal of Cancer Science and Therapy, 6 pp.350-362.

Elit, L.M., Pond, G. and Seow, H.Y., 2014. Reply to J. Menczer. Journal of Clinical Oncology, 32(19),  pp.2114-2114.

Chernesky, M., Jang, D., Gilchrist, J., Elit, L., Lytwyn, A., Smieja, M., Dockter, J., Getman, D., Reid, J. and  Hill, C., 2014. Evaluation of a new APTIMA specimen collection and transportation kit for high-risk human papillomavirus E6/E7 messenger RNA in cervical and vaginal samples. Sexually transmitted diseases, 41(6), pp.365-368.

Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Rakovitch, E., Fyles, A., Khalifa, M.A., Liu, Y. and Barbera, L., 2017. Does a groin node dissection in vulvar cancer affect groin recurrence and overall survival?: Results from a population-based cohort study. Gynecologic oncology, 144(2), pp.318-323.

Elit, L., 2014. Cervical cancer in the older woman. Maturitas, 78(3), pp.160-167.

Elit, L.M. and Hirte, H., 2014. Management of advanced or recurrent cervical cancer: chemotherapy and beyond. Expert review of anticancer therapy, 14(3), pp.319-332.

Elit, L., 2014. Role of cervical screening in older women. Maturitas, 79(4), pp.413-420.

Chernesky, M., Jang, D., Gilchrist, J., Randazzo, J., Elit, L., Lytwyn, A., Smieja, M., Reid, J. and Hill, C., 2014. Ease and Comfort of Cervical and Vaginal Sampling for Chlamydia trachomatis and Trichomonas vaginalis with a New Aptima Specimen Collection and Transportation Kit. Journal of clinical microbiology, 52(2), pp.668-670.

Vicus, D., Sutradhar, R., Lu, Y., Elit, L., Kupets, R., Paszat, L. and Investigators of the Ontario Cancer Screening Research Network, 2014. The association between cervical cancer screening and mortality from cervical cancer: A population based case–control study. Gynecologic oncology, 133(2), pp.167-171.

Elit, L.M., O’Leary, E.M., Pond, G.R. and Seow, H.Y., 2013. Impact of wait times on survival for women with uterine cancer. Journal of Clinical Oncology, 32(1), pp.27-33.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2014. Trends in incidence and survival of women with invasive vulvar cancer in the United States and Canada: a population-based study. Gynecologic oncology, 134(2), pp.314-318.

Kroft, J., Li, Q., Saskin, R., Elit, L., Bernardini, M.Q. and Gien, L.T., 2014. Trends over Time and Regional Variation in the Use of Laparoscopic Hysterectomy for the Treatment of Endometrial Cancer in the Province of Ontario, Canada. Journal of Minimally Invasive Gynecology, 21(6), p.S10.

Hunt M, Schwartz L, Pringle J, Boulanger R, Nouvet E, O’Mathúna D, Arya N, Bernard C, Beukeboom C,  Calain P, de Laat S, Eckenwiler L, Elit L, Fraser V, Gillespie LA, Johnson K, Meagher R, Nixon S, Olivier C, Pakes B,  Redwood-Campbell L, Reis A, Renaldi T, Singh J, Smith M, Von Schreeb J A research agenda for humanitarian  health ethics. PLoS Curr. 12;6

Barbera, L., Gien, L.T., Sutradhar, R., Thomas, G.M., Covens, A.L., Elit, L.M., Fyles, A., Rakovitch, E. and  Khalifa, M., 2014. Frequency of missing data from vulvar carcinoma pathology reports: Results from a population-based cohort. Gynecologic Oncology, 133, p.192.

Broomfield, J.A., Hirte, H., Elit, L., Kong, I., Patel, M., Voruganti, S., Smith, C., Chow, T. and Swaminath, A., 2014. Stereotactic Ablative Radiation Therapy for Gynecological Malignancies in the Oligometastatic Setting. International Journal of Radiation Oncology• Biology• Physics, 90(1), p.S908.

Stark, D., Nankivell, M., Pujade-Lauraine, E., Kristensen, G., Elit, L., Stockler, M., Hilpert, F., Cervantes, A., Brown, J., Lanceley, A. and Velikova, G., 2013. Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial. The lancet oncology, 14(3), pp.236-243.

Reade, C.J., Riva, J.J., Busse, J.W., Goldsmith, C.H. and Elit, L., 2013. Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysis. Gynecologic oncology, 130(3),  pp.674-681.

Eiriksson, L., Reade, C.J. and Elit, L., 2013. Meeting highlights: International Gynecologic Cancer Society (IGCS 2012). Gynecologic oncology, 128(1), pp.12-14.

Finch, A., Metcalfe, K.A., Chiang, J., Elit, L., McLaughlin, J., Springate, C., Esplen, M.J., Demsky, R., Murphy, J., Rosen, B. and Narod, S.A., 2013. The impact of prophylactic salpingo-oophorectomy on quality of life and psychological distress in women with a BRCA mutation. Psycho-Oncology, 22(1), pp.212-219.

Elit, L., Saskin, R., Raut, R., Elliott, L., Murphy, J. and Marrett, L., 2013. Sociodemographic factors associated with cervical cancer screening coverage and follow-up of high grade abnormal results in a population-based cohort. Gynecologic oncology, 128(1), pp.95-100.

Elit, L. and Hirte, H., 2013. Palliative systemic therapy for women with recurrent epithelial ovarian cancer: current options. OncoTargets Ther, 6, pp.107-18.

Chernesky, M., Jang, D., Gilchrist, J., Randazzo, J., Elit, L., Lytwyn, A., Smieja, M., Reid, J. and Hill, C.,  2013. Ease and comfort of a new APTIMA specimen collection and transportation kit with cervical and vaginal sampling for Chlamydia trachomatis and Trichomonas vaginalis. Journal of clinical microbiology, pp.JCM-02923.

Elit, L., Charles, C., Gafni, A., Gold, I., Ranford, J. and Gold, S.T., 2013. How oncologists communicate  information to women with recurrent ovarian cancer in the context of treatment decision making in the medical encounter. Gynecologic Oncology, 130(1), p.e112.

Bell, K., Scott, M., Pond, G., Piccinin, C. and Amer, M., 2013. Genetic Counselling Referral Rates and Uptake of BRCA1 and BRCA2 Testing among Women Diagnosed with Serous Ovarian Cancer in a Tertiary Care Cancer Centre. J Genet Syndr Gene Ther, 4(156), p.2.

Ray-Coquard, I., Haluska, P., O’Reilly, S., Cottu, P.H., Elit, L., Provencher, D.M., Beckmann, M.W., Bosserman, L.D., Jacod, S., Houe, V. and Loberg, R.D., 2013. A multicenter open-label phase II study of the efficacy and safety of ganitumab (AMG 479), a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R) as second-line therapy in patients with recurrent platinum-sensitive ovarian cancer. Journal of Clinical Oncology, 31(15) Suppl, pp. 5515-5515.

Murphy, K.J., Elit, L., 2013. Cervical screening guidelines — discordance discussed [eletter]. CMAJ; 2013 Mar. 22.

Schwartz, L., Hunt, M., Sinding, C., Elit, L., Redwood-Campbell, L., Adelson, N., de Laat, S., and Ranford, J., 2013. La déontologie des activités cliniques occidentales est-elle applicable aux contextes humanitaires a l’étranger?. In: Abu-Sada C, ed. Jeux de miroir: Réflexions sur MSF et l’action humanitaire. Lausanne, Switzerland: Antipodes:77-92.

Lewis, G.H., DeScipio, C., Murphy, K.M., Haley, L., Beierl, K., Mosier, S., Tandy, S., Cohen, D.S., Lytwyn, A., Elit, L. and Vang, R., 2013. Characterization of androgenetic/biparental mosaic/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease. International Journal of Gynecological Pathology, 32(2), pp.199-214.

O’Leary, E., Elit, L., Pond, G. and Seow, H., 2013. The wait time creep: Changes in the surgical wait time for women with uterine cancer in Ontario, Canada, during 2000–2009. Gynecologic oncology, 131(1), pp.151-157.

Goodwin, R.A., Jamal, R., Tu, D., Walsh, W., Dancey, J., Oza, A.M., Elit, L. and Eisenhauer, E.A., 2013. Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer. Gynecologic oncology, 131(2), pp.315-320.

Elit, L., Charles, C., Gafni, A., Ranford, J., Gold, S.T. and Gold, I., 2012. Walking a tightrope: oncologists’ perspective on providing information to women with recurrent ovarian cancer (ROC) during the medical encounter. Supportive Care in Cancer, 20(10), pp.2327-2333.

Reade, C. and Elit, L., 2012. Trends in gynecologic cancer care in North America. Obstetrics and gynecology clinics of North America, 39(2), pp.107-129.

Reade, C.J., Riva, J.J., Busse, J.W., Goldsmith, C.H. and Elit, L., 2013. Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysis. Gynecologic oncology, 130(3),  pp.674-681.

Eva Grunfeld, Rahim Moineddin, Nadia Gunraj  M. Elisabeth del Giudice,  David C. Hodgson, Janice Kwon, Laurie Elit. A population based longitudinal study of cancer screening practices of cancer survivors. Canadian Family Physician 2012;58(9);980-6

Elit L, Lee A, Swynstun L, Liaw P, Julian J, Hoskins P, Parpeer S, Julian D, Levine M. Dalteparin low molecular weight heparin (LMWH) in ovarian cancer: a phase II randomized study. Thrombosis Research 2012, 130(6)894-900

Jason E. Dodge,  Allan L. Covens, Christina Lacchetti, Laurie M. Elit,  Tien Le, Michaela Devries-Aboud, Michael Fung Kee Fung and The Gynecologic Cancer Disease Site Group. Preoperative identification of a suspicious adnexal mass: A systematic review and meta-analysis. Gyn Onc 2012;126:157-166

Rosen, B., Dodge, J., Giede, C., Jimenez, W., Cibulska, P., Sinesat, S., Bernardini, M., Mcalpine, J., Finlayson, S., Miller, D. and Elkanah, O., 2012. Implementation of oncology surgery in Western Kenya. Canadian Medical Association Journal, 55(4), p.284.

Ginsburg, O.M., Hanna, T.P., Vandenberg, T., Joy, A.A., Clemons, M., Game, M., MacCormick, R., Elit, L.M.,  Rosen, B., Rahim, Y. and Geddie, W., 2012. The global cancer epidemic: opportunities for Canada in low-and middle-income countries. Canadian Medical Association Journal, 184(15), pp.1699-1704.

Elit, L., Lytwyn, A. and Akhtar-Danesh, N., 2012. Long-Term Trends in the Survival of Women with Endometrial Cancer in Canada: A Population-Based Study. Journal of Cancer Therapy, 3(05), p.853.

Kollmannsberger C, Hirte H , Siu LL, Mazurka J, Chi K, Elit L, Walsh W, Sederias J, Chen H, Eisenhauer EA, Oza AM. Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: A NCIC-CTG phase I, open-label, dose escalation study (IND 179) Annals of Oncology 2012;23(1);238-44

Elit, L.M., Lee, A.Y., Parpia, S., Swystun, L.L., Liaw, P.C., Hoskins, P., Julian, D.H., Julian, J.A. and Levine, M.N., 2012. Dalteparin low molecular weight heparin (LMWH) in ovarian cancer: a phase II randomized  study. Thrombosis research, 130(6), pp.894-900.

Grunfeld, E., Moineddin, R., Gunraj, N., Del Giudice, M.E., Hodgson, D.C., Kwon, J.S. and Elit, L., 2012. Cancer screening practices of cancer survivors Population-based, longitudinal study. Canadian Family Physician, 58(9), pp.980-986.

Schwartz, L., Hunt, M., Sinding, C., Elit, L., Redwood-Campbell, L., Adelson, N. and de Laat, S., 2012. Models for humanitarian health care ethics. Public Health Ethics, 5(1), pp.81-90.

Lawson, L., Lytwyn, A., Jang, D., Howard, M., Elit, L., Onuma, K., Klingel, M., Toor, R., Gilchrist, J.,  Ecobichon-Morris, A. and Smieja, M., 2012. Comparison of APTIMA HPV E6/E7 mRNA and Hybrid Capture 2 assays using wet and dry self-collected flocked vaginal swabs and PreservCyt L-Pap samples. Journal of Analytical  Oncology, 1(2), pp.149-154.

Hunt, M.R., Schwartz, L., Sinding, C. and Elit, L., 2014. The ethics of engaged presence: a framework for health professionals in humanitarian assistance and development work. Developing world bioethics, 14(1), pp.47-55.

Hunt, M.R., Schwartz, L. and Elit, L., 2012. Experience of ethics training and support for health care professionals in international aid work. Public Health Ethics, 5(1), pp.91-99.

Akhtar-Danesh, N., Lytwyn, A. and Elit, L., 2012. Five-year trends in mortality indices among gynecological cancer patients in Canada. Gynecologic oncology, 127(3), pp.620-624.

Dodge, J.E., Covens, A.L., Lacchetti, C., Elit, L.M., Le, T., Devries–Aboud, M., Fung-Kee-Fung, M. and Gynecology Cancer Disease Site Group, 2012. Management of a suspicious adnexal mass: a clinical practice guideline. Current oncology, 19(4), p.e244.

Trim, K., Nagji, N., Elit, L. and Roy, K., 2012. Parental knowledge, attitudes, and behaviours towards human papillomavirus vaccination for their children: a systematic review from 2001 to 2011. Obstetrics and gynecology international, 2012.

Elit, L., Krzyzanowska, M., Saskin, R., Barbera, L., Razzaq, A., Lofters, A., Yeritsyan, N. and Bierman, A., 2012. Sociodemographic factors associated with cervical cancer screening and follow-up of abnormal results. Canadian Family Physician, 58(1), pp.e22-e31.

Covens, A.L., Dodge, J.E., Lacchetti, C., Elit, L.M., Le, T., Devries-Aboud, M., Fung-Kee-Fung, M. and Gynecology Cancer Disease Site Group, 2012. Surgical management of a suspicious adnexal mass: a systematic review. Gynecologic oncology, 126(1), pp.149-156.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2012. Temporal trends in the relative survival among women with cervical cancer in Canada: a population-based study. International Journal of Gynecological Cancer, 22(7), pp.1208-1213.

Gladieff, L., Ferrero, A., De Rauglaudre, G., Brown, C., Vasey, P., Reinthaller, A., Pujade-Lauraine, E., Reed, N., Lorusso, D., Siena, S. and Helland, H., 2012. Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial. Annals of oncology, 23(5), pp.1185-1189.

BIO

Laurie Elit MD MSc FRCS (C) is a professor in the Department of Obstetrics & Gynecology at McMaster University and the division head for gynecologic oncology at Hamilton Health Sciences Centre-Juravinski Cancer Centre. She obtained her medical degree at University of Western Ontario, her fellowship in obstetrics and gynecology at University of Western Ontario, and her gynecologic oncology training at Pennsylvania Hospital, Philadelphia and the University of Toronto. She completed a master’s in health research and methodology at McMaster University. Her research interests involve health services delivery for gynecologic cancer in particular ovarian cancer, treatment decision making with a focus in ovarian cancer and clinical trials with a focus in preinvasive disease. She is the gynecologic disease site team lead for Cancer Care Ontario’s Program in Evidence-Based Care. She has volunteered as an educator, clinician and administrator in several low and middle income settings (i.e., Papua New Guinea, Haiti, Bangladesh, Pakistan, Mongolia, Macedonia). Dr. Elit will be increasing her time commitment to global health endeavors working at Mbingo Baptist Hospital, Cameroon beginning January 2021.

AWARDS

• 2020 Mohide Lectureship, McMaster University, Hamilton
• 2019 Ontario Society of Obstetrics and Gynecology life time achievement award
• 2019 Hamilton Health Sciences Centre Medical Staff Award for Community or Global Humanitarianism
• 2019 Dr. John Mazurka Award for Clinical Surgical Teaching
• 2016 Gynecologic Oncology Canada Presidential Medal
• 2016 Hamilton Health Sciences Centre Medical Staff Association President’s Award for Distinguished Long Service
• 2014 Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Gynecologic Surgical Training. Department of Obstetrics & Gynecology.
• 2011 American College of Obstetricians and Gynecologists (CREOG) National Faculty Award for Excellence in Resident Education
• 2007 MacKenzie Fellowship in Surgery, Royal College of Physicians and Surgeons Canada
• 2006 Clinical Traineeship Grant from the Royal College of Physicians and Surgeons Canada

RESEARCH INTERESTS

• Health Services Research in Gynecologic Oncology specifically ovarian cancer.
• Randomized trials specifically in CIN 1, PET Scanning for cervical cancer and ovarian cancer.
• Treatment decision making in ovarian cancer.

Research Themes

Ovarian cancer; Cervical cancer; Quality improvement; Screening; Pre-invasive disease

PUBLICATIONS

Francis JA, Elit L, Coakley N, MacKay H And Gynecologic Cancer Disease Site Group. Systematic therapy for recurrent epithelial ovarian cancer: a clinical practice guideline. Current Oncology. 2017;24(6):e540-e546 doi: 10.3747/co.24.3824

Elit L, Fyles A, Gu C, Pond G, D’Souza D, Samant R, Anthes M, Thomas G, Filion M, Arsenault J, Dayes I, Whelan T, Gulenchyn K, Metser U, Dhamanaskar K, Levine M. Impact of Positron Emission Tomography (PET) imaging in Women with locally advanced cervical cancer: a Randomized trial. JAMA Open Network 2018:1(5):e182081 doi:10.1001/jamanetworkopen.2018.2081 14Sep2018 pp1-13

Shakeel, S., Elit, L., Akhtar-Danesh, N., Schneider, L. and Finley, C., 2017. Care Delivery Patterns, Processes, and Outcomes for Primary Ovarian Cancer Surgery: A Population-Based Review Using a National Administrative  Database. Journal of Obstetrics and Gynaecology Canada, 39(1), pp.25-33.

Barbera, L., Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Fyles, A., Rakovitch, E., Liu, Y. and  Khalifa, M., 2017. The Added Value of Pathology Review in Vulvar Cancer: Results From a Population-based Cohort Study. International Journal of Gynecological Pathology, 36(2), pp.107-110.

McGee, J., Panabaker, K., Leonard, S., Ainsworth, P., Elit, L. and Shariff, S.Z., 2017. Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario. International Journal of Gynecological Cancer, 27(3), pp.437-443.

Serrano Aybar, P.E., Dhamanaskar, K., Elit, L., Parpia, S., Linkins, L.A., Simunovic, M., Ruo, L., Bhandari, M. and Levine, M.N., 2017. Incidence of venous thromboembolic events following major pelvic and abdominal surgery for cancer. Journal of Clinical Oncology, 35(4) Suppl, pp. 478-478.

Elit, L., 2016. Cervical cancer screening in women over 65. PRO: Are we asking the right question?. Gynecologic Oncology, 142(3), pp.381-382.

Bezanson, K., Nouvet, E., Hunt, M., de Laat, S., Elit, L., Bernard, C. and Schwartz, L., 2016. D08-C The Place of Palliative Care in Humanitarian Response. Journal of Pain and Symptom Management, 52(6), pp.e34-e35.

Mackay, H., Soobrian, J., Murphy, J., Elit, L., Milosevic, M.F., Gollnow, A., Ross, J. and Holloway, C., 2016. Pathway map development as an approach to identifying priority areas for quality improvement in Ontario. Journal of Clinical Oncology, 34(7) Suppl pp. 108-108.

Le, T., Kennedy, E.B., Dodge, J. and Elit, L., 2016. Follow-up of patients who are clinically disease-free after primary treatment for fallopian tube, primary peritoneal, or epithelial ovarian cancer: a Program in Evidence-Based Care guideline adaptation. Current Oncology, 23(5), p.343.

Elit, L., Kennedy, E.B., Fyles, A. and Metser, U., 2016. Follow-up for cervical cancer: a Program in Evidence-Based Care systematic review and clinical practice guideline update. Current Oncology, 23(2), p.109.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2016. Challenges in striving to simultaneously achieve multiple resource allocation goals: the pan-Canadian Oncology Drug Review (pCODR) example. Journal of Market  Access & Health Policy, 4.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Pond, G., Elit, L. and Kong, I., 2016. The Pathologic and Treatment Factors Associated With Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. International Journal of Radiation Oncology• Biology• Physics, 96(2), p.E315.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Pond, G., Memon, S., Elit, L. and Kong, I., 2016. 228: Pathologic and Treatment Factors Associated with Recurrence in Stage IA Serous Adenocarcinoma of the Uterus. Radiotherapy and Oncology, 120, p.S83.

Donovan, E., Eiriksson, L., Reade, C., Kaur, H., Memon, S., Elit, L. and Kong, I., 2016. Outcomes of Stage IA  Serous Endometrial Adenocarcinoma. Brachytherapy, 15, pp.S111-S112.

Voruganti, T., Moineddin, R., Jembere, N., Elit, L., Grunfeld, E. and Lofters, A.K., 2016. Comparing stage of  diagnosis of cervical cancer at presentation in immigrant women and long-term residents of Ontario: a retrospective  cohort study. CMAJ open, 4(3), p.E424.

Elit, L., 2015. Wait times from diagnosis to treatment in cancer. Journal of gynecologic oncology, 26(4),  pp.246-248.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2015. Is there an economic rationale for cancer drugs to  have a separate reimbursement review process for resource allocation purposes?. Pharmacoeconomics, 33(3), pp.235-241.

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS-0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Fung-Kee-Fung, M., Kennedy, E.B., Biagi, J., Colgan, T., D’Souza, D., Elit, L.M., Hunter, A., Irish, J.,  McLeod, R. and Rosen, B., 2015. The optimal organization of gynecologic oncology services: a systematic review. Current Oncology, 22(4), p.e282.

Elit L, Pond G, Seow H. Letter to the Editor. Wait Time and Survival for Type 1 Endometrial Cancer. Obstetrics and Gynecology 2015:125(6):

Kroft, J., Li, Q., Saskin, R., Elit, L., Bernardini, M.Q. and Gien, L.T., 2015. Trends over time in the use of laparoscopic hysterectomy for the treatment of endometrial cancer. Gynecologic oncology, 138(3), pp.536-541.

Elit, L.M., Pond, G. and Seow, H., 2015. Time interval between endometrial biopsy and surgical staging for  type I endometrial cancer: association between tumor characteristics and survival outcome. Obstetrics &  Gynecology, 125(6), pp.1497-1498.

McDonald, H., Charles, C., Elit, L. and Gafni, A., 2015. The Silence in Hoch et al.’s Commentary about the  Rationale for and Objective (s) of Canada’s Separate HTA Process for Cancer Drugs: The Importance of Transparency and Accountability when Allocating Taxpayers’ Dollars. PharmacoEconomics, 33(8), pp.883-886.

Elit, L.M., Fyles, A.W., Gu, C.S., Pond, G.R., D’Souza, D., Samant, R., Anthes, M., Thomas, G., Fillion, M.,  Arsenault, J. and Dayes, I., 2015. The role of PET-CT in treatment decision making for women with locally advanced cervical cancer. Journal of Clinical Oncology, 33(15) Suppl, pp. 5523-5523.

Murphy, J., Varela, N.P., Elit, L., Lytwyn, A., Yudin, M., Shier, M., Wu, V. and El-Khatib, S., 2015. The organization of colposcopy services in Ontario: recommended framework. Current Oncology, 22(4), p.287.

Elit, L., Charles, C.A. and Gafni, A., 2015. Oncologists’ Perceptions of Recurrent Ovarian Cancer Patients’  Preference for Participation in Treatment Decision Making and Strategies for When and How to Involve Patients in This Process. International Journal of Gynecological Cancer, 25(9), pp.1717-1723.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2015. Further Insights Into Long-Term Trends in Relative Survival of Vulvar Cancer Patients: A Population-Based Study. International Journal of Gynecological Cancer, 25(1), pp.125-130.

Fung-Kee-Fung, M., Kennedy, E.B., Biagi, J., Colgan, T., D’Souza, D., Elit, L.M., Hunter, A., Irish, J., McLeod, R. and Rosen, B., 2015. An organizational guideline for gynecologic oncology services. International Journal of Gynecological Cancer, 25(4), pp.551-558.

Elit LM, Charles CA, Gafni A. Oncologists’ perceptions of recurrent ovarian cancer patients’ preference for participation in treatment decision and making and strategies for when and how to involve patients in this process. IJGC, 25(9), 1717-23.

Elit, L. and Reade, C.J., 2015. Recommendations for follow-up care for gynecologic cancer survivors. Obstetrics & Gynecology, 126(6), pp.1207-1214.

Hirte, H., Kennedy, E.B., Elit, L. and Fung, M.F.K., 2015. Systemic therapy for recurrent, persistent, or metastatic cervical cancer: a clinical practice guideline. Current Oncology, 22(3), p.211.

Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Rakovitch, E., Fyles, A., Khalifa, M.A., Liu, Y. and Barbera, L., 2015. Patient, tumor, and health system factors affecting groin node dissection rates in vulvar carcinoma: A population-based cohort study. Gynecologic oncology, 139(3), pp.465-470.

Elit, L. and Reade, C.J., 2015. Recomendaciones para la Atención de Seguimiento a Sobrevivientes de Cáncer Ginecológico. Obstet Gynecol, 126, pp.1207-1214.

Prummel, M.V., Young, S.W., Candido, E., Nishri, D., Elit, L. and Marrett, L.D., 2014. Cervical cancer incidence in ontario women: differing sociodemographic gradients by morphologic type (adenocarcinoma versus squamous cell). International Journal of Gynecological Cancer, 24(7), pp.1341-1346.

Tsoref, D., Welch, S., Lau, S., Biagi, J., Tonkin, K., Martin, L.A., Ellard, S., Ghatage, P., Elit, L., Mackay, H.J. and Allo, G., 2014. Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer. Gynecologic oncology, 135(2), pp.184-189.

Elit, L., and Hirte, H., 2014. Novel Targeted Therapies in Ovarian Cancer. Journal of Cancer Science and Therapy, 6 pp.350-362.

Elit, L.M., Pond, G. and Seow, H.Y., 2014. Reply to J. Menczer. Journal of Clinical Oncology, 32(19),  pp.2114-2114.

Chernesky, M., Jang, D., Gilchrist, J., Elit, L., Lytwyn, A., Smieja, M., Dockter, J., Getman, D., Reid, J. and  Hill, C., 2014. Evaluation of a new APTIMA specimen collection and transportation kit for high-risk human papillomavirus E6/E7 messenger RNA in cervical and vaginal samples. Sexually transmitted diseases, 41(6), pp.365-368.

Gien, L.T., Sutradhar, R., Thomas, G., Covens, A., Elit, L., Rakovitch, E., Fyles, A., Khalifa, M.A., Liu, Y. and Barbera, L., 2017. Does a groin node dissection in vulvar cancer affect groin recurrence and overall survival?: Results from a population-based cohort study. Gynecologic oncology, 144(2), pp.318-323.

Elit, L., 2014. Cervical cancer in the older woman. Maturitas, 78(3), pp.160-167.

Elit, L.M. and Hirte, H., 2014. Management of advanced or recurrent cervical cancer: chemotherapy and beyond. Expert review of anticancer therapy, 14(3), pp.319-332.

Elit, L., 2014. Role of cervical screening in older women. Maturitas, 79(4), pp.413-420.

Chernesky, M., Jang, D., Gilchrist, J., Randazzo, J., Elit, L., Lytwyn, A., Smieja, M., Reid, J. and Hill, C., 2014. Ease and Comfort of Cervical and Vaginal Sampling for Chlamydia trachomatis and Trichomonas vaginalis with a New Aptima Specimen Collection and Transportation Kit. Journal of clinical microbiology, 52(2), pp.668-670.

Vicus, D., Sutradhar, R., Lu, Y., Elit, L., Kupets, R., Paszat, L. and Investigators of the Ontario Cancer Screening Research Network, 2014. The association between cervical cancer screening and mortality from cervical cancer: A population based case–control study. Gynecologic oncology, 133(2), pp.167-171.

Elit, L.M., O’Leary, E.M., Pond, G.R. and Seow, H.Y., 2013. Impact of wait times on survival for women with uterine cancer. Journal of Clinical Oncology, 32(1), pp.27-33.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2014. Trends in incidence and survival of women with invasive vulvar cancer in the United States and Canada: a population-based study. Gynecologic oncology, 134(2), pp.314-318.

Kroft, J., Li, Q., Saskin, R., Elit, L., Bernardini, M.Q. and Gien, L.T., 2014. Trends over Time and Regional Variation in the Use of Laparoscopic Hysterectomy for the Treatment of Endometrial Cancer in the Province of Ontario, Canada. Journal of Minimally Invasive Gynecology, 21(6), p.S10.

Hunt M, Schwartz L, Pringle J, Boulanger R, Nouvet E, O’Mathúna D, Arya N, Bernard C, Beukeboom C,  Calain P, de Laat S, Eckenwiler L, Elit L, Fraser V, Gillespie LA, Johnson K, Meagher R, Nixon S, Olivier C, Pakes B,  Redwood-Campbell L, Reis A, Renaldi T, Singh J, Smith M, Von Schreeb J A research agenda for humanitarian  health ethics. PLoS Curr. 12;6

Barbera, L., Gien, L.T., Sutradhar, R., Thomas, G.M., Covens, A.L., Elit, L.M., Fyles, A., Rakovitch, E. and  Khalifa, M., 2014. Frequency of missing data from vulvar carcinoma pathology reports: Results from a population-based cohort. Gynecologic Oncology, 133, p.192.

Broomfield, J.A., Hirte, H., Elit, L., Kong, I., Patel, M., Voruganti, S., Smith, C., Chow, T. and Swaminath, A., 2014. Stereotactic Ablative Radiation Therapy for Gynecological Malignancies in the Oligometastatic Setting. International Journal of Radiation Oncology• Biology• Physics, 90(1), p.S908.

Stark, D., Nankivell, M., Pujade-Lauraine, E., Kristensen, G., Elit, L., Stockler, M., Hilpert, F., Cervantes, A., Brown, J., Lanceley, A. and Velikova, G., 2013. Standard chemotherapy with or without bevacizumab in advanced ovarian cancer: quality-of-life outcomes from the International Collaboration on Ovarian Neoplasms (ICON7) phase 3 randomised trial. The lancet oncology, 14(3), pp.236-243.

Reade, C.J., Riva, J.J., Busse, J.W., Goldsmith, C.H. and Elit, L., 2013. Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysis. Gynecologic oncology, 130(3),  pp.674-681.

Eiriksson, L., Reade, C.J. and Elit, L., 2013. Meeting highlights: International Gynecologic Cancer Society (IGCS 2012). Gynecologic oncology, 128(1), pp.12-14.

Finch, A., Metcalfe, K.A., Chiang, J., Elit, L., McLaughlin, J., Springate, C., Esplen, M.J., Demsky, R., Murphy, J., Rosen, B. and Narod, S.A., 2013. The impact of prophylactic salpingo-oophorectomy on quality of life and psychological distress in women with a BRCA mutation. Psycho-Oncology, 22(1), pp.212-219.

Elit, L., Saskin, R., Raut, R., Elliott, L., Murphy, J. and Marrett, L., 2013. Sociodemographic factors associated with cervical cancer screening coverage and follow-up of high grade abnormal results in a population-based cohort. Gynecologic oncology, 128(1), pp.95-100.

Elit, L. and Hirte, H., 2013. Palliative systemic therapy for women with recurrent epithelial ovarian cancer: current options. OncoTargets Ther, 6, pp.107-18.

Chernesky, M., Jang, D., Gilchrist, J., Randazzo, J., Elit, L., Lytwyn, A., Smieja, M., Reid, J. and Hill, C.,  2013. Ease and comfort of a new APTIMA specimen collection and transportation kit with cervical and vaginal sampling for Chlamydia trachomatis and Trichomonas vaginalis. Journal of clinical microbiology, pp.JCM-02923.

Elit, L., Charles, C., Gafni, A., Gold, I., Ranford, J. and Gold, S.T., 2013. How oncologists communicate  information to women with recurrent ovarian cancer in the context of treatment decision making in the medical encounter. Gynecologic Oncology, 130(1), p.e112.

Bell, K., Scott, M., Pond, G., Piccinin, C. and Amer, M., 2013. Genetic Counselling Referral Rates and Uptake of BRCA1 and BRCA2 Testing among Women Diagnosed with Serous Ovarian Cancer in a Tertiary Care Cancer Centre. J Genet Syndr Gene Ther, 4(156), p.2.

Ray-Coquard, I., Haluska, P., O’Reilly, S., Cottu, P.H., Elit, L., Provencher, D.M., Beckmann, M.W., Bosserman, L.D., Jacod, S., Houe, V. and Loberg, R.D., 2013. A multicenter open-label phase II study of the efficacy and safety of ganitumab (AMG 479), a fully human monoclonal antibody against insulin-like growth factor type 1 receptor (IGF-1R) as second-line therapy in patients with recurrent platinum-sensitive ovarian cancer. Journal of Clinical Oncology, 31(15) Suppl, pp. 5515-5515.

Murphy, K.J., Elit, L., 2013. Cervical screening guidelines — discordance discussed [eletter]. CMAJ; 2013 Mar. 22.

Schwartz, L., Hunt, M., Sinding, C., Elit, L., Redwood-Campbell, L., Adelson, N., de Laat, S., and Ranford, J., 2013. La déontologie des activités cliniques occidentales est-elle applicable aux contextes humanitaires a l’étranger?. In: Abu-Sada C, ed. Jeux de miroir: Réflexions sur MSF et l’action humanitaire. Lausanne, Switzerland: Antipodes:77-92.

Lewis, G.H., DeScipio, C., Murphy, K.M., Haley, L., Beierl, K., Mosier, S., Tandy, S., Cohen, D.S., Lytwyn, A., Elit, L. and Vang, R., 2013. Characterization of androgenetic/biparental mosaic/chimeric conceptions, including those with a molar component: morphology, p57 immnohistochemistry, molecular genotyping, and risk of persistent gestational trophoblastic disease. International Journal of Gynecological Pathology, 32(2), pp.199-214.

O’Leary, E., Elit, L., Pond, G. and Seow, H., 2013. The wait time creep: Changes in the surgical wait time for women with uterine cancer in Ontario, Canada, during 2000–2009. Gynecologic oncology, 131(1), pp.151-157.

Goodwin, R.A., Jamal, R., Tu, D., Walsh, W., Dancey, J., Oza, A.M., Elit, L. and Eisenhauer, E.A., 2013. Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer. Gynecologic oncology, 131(2), pp.315-320.

Elit, L., Charles, C., Gafni, A., Ranford, J., Gold, S.T. and Gold, I., 2012. Walking a tightrope: oncologists’ perspective on providing information to women with recurrent ovarian cancer (ROC) during the medical encounter. Supportive Care in Cancer, 20(10), pp.2327-2333.

Reade, C. and Elit, L., 2012. Trends in gynecologic cancer care in North America. Obstetrics and gynecology clinics of North America, 39(2), pp.107-129.

Reade, C.J., Riva, J.J., Busse, J.W., Goldsmith, C.H. and Elit, L., 2013. Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysis. Gynecologic oncology, 130(3),  pp.674-681.

Eva Grunfeld, Rahim Moineddin, Nadia Gunraj  M. Elisabeth del Giudice,  David C. Hodgson, Janice Kwon, Laurie Elit. A population based longitudinal study of cancer screening practices of cancer survivors. Canadian Family Physician 2012;58(9);980-6

Elit L, Lee A, Swynstun L, Liaw P, Julian J, Hoskins P, Parpeer S, Julian D, Levine M. Dalteparin low molecular weight heparin (LMWH) in ovarian cancer: a phase II randomized study. Thrombosis Research 2012, 130(6)894-900

Jason E. Dodge,  Allan L. Covens, Christina Lacchetti, Laurie M. Elit,  Tien Le, Michaela Devries-Aboud, Michael Fung Kee Fung and The Gynecologic Cancer Disease Site Group. Preoperative identification of a suspicious adnexal mass: A systematic review and meta-analysis. Gyn Onc 2012;126:157-166

Rosen, B., Dodge, J., Giede, C., Jimenez, W., Cibulska, P., Sinesat, S., Bernardini, M., Mcalpine, J., Finlayson, S., Miller, D. and Elkanah, O., 2012. Implementation of oncology surgery in Western Kenya. Canadian Medical Association Journal, 55(4), p.284.

Ginsburg, O.M., Hanna, T.P., Vandenberg, T., Joy, A.A., Clemons, M., Game, M., MacCormick, R., Elit, L.M.,  Rosen, B., Rahim, Y. and Geddie, W., 2012. The global cancer epidemic: opportunities for Canada in low-and middle-income countries. Canadian Medical Association Journal, 184(15), pp.1699-1704.

Elit, L., Lytwyn, A. and Akhtar-Danesh, N., 2012. Long-Term Trends in the Survival of Women with Endometrial Cancer in Canada: A Population-Based Study. Journal of Cancer Therapy, 3(05), p.853.

Kollmannsberger C, Hirte H , Siu LL, Mazurka J, Chi K, Elit L, Walsh W, Sederias J, Chen H, Eisenhauer EA, Oza AM. Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: A NCIC-CTG phase I, open-label, dose escalation study (IND 179) Annals of Oncology 2012;23(1);238-44

Elit, L.M., Lee, A.Y., Parpia, S., Swystun, L.L., Liaw, P.C., Hoskins, P., Julian, D.H., Julian, J.A. and Levine, M.N., 2012. Dalteparin low molecular weight heparin (LMWH) in ovarian cancer: a phase II randomized  study. Thrombosis research, 130(6), pp.894-900.

Grunfeld, E., Moineddin, R., Gunraj, N., Del Giudice, M.E., Hodgson, D.C., Kwon, J.S. and Elit, L., 2012. Cancer screening practices of cancer survivors Population-based, longitudinal study. Canadian Family Physician, 58(9), pp.980-986.

Schwartz, L., Hunt, M., Sinding, C., Elit, L., Redwood-Campbell, L., Adelson, N. and de Laat, S., 2012. Models for humanitarian health care ethics. Public Health Ethics, 5(1), pp.81-90.

Lawson, L., Lytwyn, A., Jang, D., Howard, M., Elit, L., Onuma, K., Klingel, M., Toor, R., Gilchrist, J.,  Ecobichon-Morris, A. and Smieja, M., 2012. Comparison of APTIMA HPV E6/E7 mRNA and Hybrid Capture 2 assays using wet and dry self-collected flocked vaginal swabs and PreservCyt L-Pap samples. Journal of Analytical  Oncology, 1(2), pp.149-154.

Hunt, M.R., Schwartz, L., Sinding, C. and Elit, L., 2014. The ethics of engaged presence: a framework for health professionals in humanitarian assistance and development work. Developing world bioethics, 14(1), pp.47-55.

Hunt, M.R., Schwartz, L. and Elit, L., 2012. Experience of ethics training and support for health care professionals in international aid work. Public Health Ethics, 5(1), pp.91-99.

Akhtar-Danesh, N., Lytwyn, A. and Elit, L., 2012. Five-year trends in mortality indices among gynecological cancer patients in Canada. Gynecologic oncology, 127(3), pp.620-624.

Dodge, J.E., Covens, A.L., Lacchetti, C., Elit, L.M., Le, T., Devries–Aboud, M., Fung-Kee-Fung, M. and Gynecology Cancer Disease Site Group, 2012. Management of a suspicious adnexal mass: a clinical practice guideline. Current oncology, 19(4), p.e244.

Trim, K., Nagji, N., Elit, L. and Roy, K., 2012. Parental knowledge, attitudes, and behaviours towards human papillomavirus vaccination for their children: a systematic review from 2001 to 2011. Obstetrics and gynecology international, 2012.

Elit, L., Krzyzanowska, M., Saskin, R., Barbera, L., Razzaq, A., Lofters, A., Yeritsyan, N. and Bierman, A., 2012. Sociodemographic factors associated with cervical cancer screening and follow-up of abnormal results. Canadian Family Physician, 58(1), pp.e22-e31.

Covens, A.L., Dodge, J.E., Lacchetti, C., Elit, L.M., Le, T., Devries-Aboud, M., Fung-Kee-Fung, M. and Gynecology Cancer Disease Site Group, 2012. Surgical management of a suspicious adnexal mass: a systematic review. Gynecologic oncology, 126(1), pp.149-156.

Akhtar-Danesh, N., Elit, L. and Lytwyn, A., 2012. Temporal trends in the relative survival among women with cervical cancer in Canada: a population-based study. International Journal of Gynecological Cancer, 22(7), pp.1208-1213.

Gladieff, L., Ferrero, A., De Rauglaudre, G., Brown, C., Vasey, P., Reinthaller, A., Pujade-Lauraine, E., Reed, N., Lorusso, D., Siena, S. and Helland, H., 2012. Carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in partially platinum-sensitive ovarian cancer patients: results from a subset analysis of the CALYPSO phase III trial. Annals of oncology, 23(5), pp.1185-1189.

BIO

Dr. Susan Ellis is an associate professor in the Department of Obstetrics & Gynecology at McMaster University and chief of the Department and Active Medical Staff at St. Joseph’s Healthcare, Hamilton. She completed her residency in obstetrics and gynecology at McMaster University.

Throughout her career, Dr. Ellis’s dedication to education has earned her several awards, including the McMaster Department of Obstetrics & Gynecology Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Obstetrical Teaching.

In 2014, she attended the Mayo Clinic for Instructor Development: Simulation-Based Education Design and Debriefing. She led the development of the postgraduate simulation program and is a dedicated simulation educator and researcher. In her role as chief, her team implemented an interprofessional and multidisciplinary in-situ simulation program.

AWARDS

• 2020: St. Joseph’s Healthcare Annual Consultant’s Award
• 2014: McMaster Department of Obstetrics & Gynecology, Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Obstetrical Teaching
• 2011: Michael G. DeGroote School of Medicine, Residents’ Award for Excellence in Teaching Obstetrics and Gynecology
• 2010–11: The Association of Professionals in Obstetrics and Gynaecology (APOG), Carl Nimrod Educator Award
• 2007: McMaster University Medical Centre, Association of Professors of Gynecology & Obstetrics (APGO) Excellence in Teaching for Undergraduate Education
• 2004: McMaster University, McMaster University Residents Award for Excellence in Teaching, Obstetrics and Gynecology
• 2000: McMaster University, Distinguished Service Award, Department of Obstetrics & Gynecology

RESEARCH INTERESTS

• Simulation
• Quality and Patient Safety

PUBLICATIONS

2017. Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, E. (2017).  Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384. P-OBS-JM-061

2017. Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, S., 2017. P-OBS-JM-061 Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery: A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

2009. Torrance SM, Muhn N, Ellis S, Rebello R, Ramanna R. Role of Dynamic MRI in Surgical Decision-making for a Postpartum Woman With a Prolapsed Degenerating Uterine Leiomyoma, J Obstet Gynaecol Can. 2009 May;31(5):446-51.

2009. Torrance, S.M., Muhn, N., Ellis, S., Rebello, R. and Ramanna, R., 2009. Role of DynamicMRI in Surgical Decision-making for a Postpartum Woman With a Prolapsed Degenerating Uterine Leiomyoma. Journal of Obstetrics and Gynaecology Canada, 31(5), pp.446-451.

BIO

Dr. Susan Ellis is an associate professor in the Department of Obstetrics & Gynecology at McMaster University and chief of the Department and Active Medical Staff at St. Joseph’s Healthcare, Hamilton. She completed her residency in obstetrics and gynecology at McMaster University.

Throughout her career, Dr. Ellis’s dedication to education has earned her several awards, including the McMaster Department of Obstetrics & Gynecology Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Obstetrical Teaching.

In 2014, she attended the Mayo Clinic for Instructor Development: Simulation-Based Education Design and Debriefing. She led the development of the postgraduate simulation program and is a dedicated simulation educator and researcher. In her role as chief, her team implemented an interprofessional and multidisciplinary in-situ simulation program.

AWARDS

• 2020: St. Joseph’s Healthcare Annual Consultant’s Award
• 2014: McMaster Department of Obstetrics & Gynecology, Certificate of Excellence for Sustained and Continuous Pursuit of Excellence in Obstetrical Teaching
• 2011: Michael G. DeGroote School of Medicine, Residents’ Award for Excellence in Teaching Obstetrics and Gynecology
• 2010–11: The Association of Professionals in Obstetrics and Gynaecology (APOG), Carl Nimrod Educator Award
• 2007: McMaster University Medical Centre, Association of Professors of Gynecology & Obstetrics (APGO) Excellence in Teaching for Undergraduate Education
• 2004: McMaster University, McMaster University Residents Award for Excellence in Teaching, Obstetrics and Gynecology
• 2000: McMaster University, Distinguished Service Award, Department of Obstetrics & Gynecology

RESEARCH INTERESTS

• Simulation
• Quality and Patient Safety

PUBLICATIONS

2017. Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, E. (2017).  Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384. P-OBS-JM-061

2017. Banner, H., Columbus, L., Mueller, V., Donnery, C., Dore, K., Murray-Davis, B. and Ellis, S., 2017. P-OBS-JM-061 Interprofessional Perinatal Simulation as a Teaching Tool for Trainees in Obstetrics and Midwifery: A Pilot Project. Journal of Obstetrics and Gynaecology Canada, 39(5), p.384.

2009. Torrance SM, Muhn N, Ellis S, Rebello R, Ramanna R. Role of Dynamic MRI in Surgical Decision-making for a Postpartum Woman With a Prolapsed Degenerating Uterine Leiomyoma, J Obstet Gynaecol Can. 2009 May;31(5):446-51.

2009. Torrance, S.M., Muhn, N., Ellis, S., Rebello, R. and Ramanna, R., 2009. Role of DynamicMRI in Surgical Decision-making for a Postpartum Woman With a Prolapsed Degenerating Uterine Leiomyoma. Journal of Obstetrics and Gynaecology Canada, 31(5), pp.446-451.

BIO

Dr. Faghih completed medical school in Iran at Isfahan University of Medical Sciences, graduating at the top of her class. After moving to Canada, she pursued her residency in obstetrics and gynecology. She completed a two-year residency in gynecologic reproductive endocrinology and infertility at McMaster University, graduating in March of 2010. Dr. Faghih has been involved in teaching since 2007 as an instructor for the obstetrics and gynecology residency and clerkship programs at McMaster University. She was also extensively involved in the process of starting an accredited reproductive endocrinology and infertility fellowship program at McMaster. ONE Fertility Clinic is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges.

PUBLICATIONS

2016. Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.

2016. Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

2013. Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

2011. Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

2008. Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.

BIO

Dr. Faghih completed medical school in Iran at Isfahan University of Medical Sciences, graduating at the top of her class. After moving to Canada, she pursued her residency in obstetrics and gynecology. She completed a two-year residency in gynecologic reproductive endocrinology and infertility at McMaster University, graduating in March of 2010. Dr. Faghih has been involved in teaching since 2007 as an instructor for the obstetrics and gynecology residency and clerkship programs at McMaster University. She was also extensively involved in the process of starting an accredited reproductive endocrinology and infertility fellowship program at McMaster. ONE Fertility Clinic is a state-of-the-art fertility clinic with the latest in technology. ONE Fertility is affiliated with McMaster University through teaching and collaborative research. The clinic will provide a much needed service to the more than 15% of the population affected by fertility challenges.

PUBLICATIONS

2016. Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.

2016. Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

2013. Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

2011. Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

2008. Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.

BIO

Dr. Fedorkow graduated with an MD from the University of Calgary where she also obtained her FRCSC in obstetrics and gynecology. After completing sub-specialty training in urogynaecology and earning a MSc in epidemology, she joined the Department of Obstetrics & Gynecology at McMaster University. She holds the rank of professor emeritus.

Dr. Fedorkow served as the department’s continuing medical education director, undergraduate program director and urogynecology program director. She is a past president of the Society of Obstetricians and Gynaecologists of Canada.

RESEARCH INTERESTS

Her clinical and research interests have included menopause, urogynaecology, conservative management of pelvic floor dysfunction and undergraduate medical education.

PUBLICATIONS

Fedorkow, D., 2017. O-GYN-UROGYN-MD-006 Acceptability and Effectiveness of an External Support Device for Managing Pelvic Floor Prolapse. Journal of Obstetrics and Gynaecology Canada, 39(5), pp.388-389.

Fedorkow, D., Green, S., Donegan, E., Frey, B., Key, B., Streiner, D. and McCabe, R., 2017. O-GYN-MD-054 Cognitive Behaviour Therapy for Menopausal Symptoms (CBT-MENO): Preliminary Results from a Randomized Controlled Trial (RCT)–A Mid-Way, Interim Analysis. Journal of Obstetrics and Gynaecology Canada, 39(5), p.388.

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

2016. Syan, S.K., Steiner, M., Mahoney, J.L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Minuzzi, L., 2016, December. Resting-state fMRI after Acute Tryptophan Depletion in Perimenopause Women on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1400-1400).

2016. Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Fedorkow, D.M., 2015. Review: In peri-or postmenopausal women, DHEA does not improve symptoms and increases androgenic side effects. Annals of internal medicine, 162(10), pp.JC9-JC9.

Fedorkow, D., 2011. Annual screening with CA-125 and transvaginal ultrasonography did not reduce ovarian cancer incidence or mortality. Annals of internal medicine, 155(6), pp.JC3-8.

Fedorkow D., 2011. Hormone therapy increased risk for kidney stones in healthy postmenopausal women. Annals of Internal Medicine. 154:JC3-10. doi: 10.7326/0003-4819-154-6-201103150-02010

Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.

BIO

Dr. Fedorkow graduated with an MD from the University of Calgary where she also obtained her FRCSC in obstetrics and gynecology. After completing sub-specialty training in urogynaecology and earning a MSc in epidemology, she joined the Department of Obstetrics & Gynecology at McMaster University. She holds the rank of professor emeritus.

Dr. Fedorkow served as the department’s continuing medical education director, undergraduate program director and urogynecology program director. She is a past president of the Society of Obstetricians and Gynaecologists of Canada.

RESEARCH INTERESTS

Her clinical and research interests have included menopause, urogynaecology, conservative management of pelvic floor dysfunction and undergraduate medical education.

PUBLICATIONS

Fedorkow, D., 2017. O-GYN-UROGYN-MD-006 Acceptability and Effectiveness of an External Support Device for Managing Pelvic Floor Prolapse. Journal of Obstetrics and Gynaecology Canada, 39(5), pp.388-389.

Fedorkow, D., Green, S., Donegan, E., Frey, B., Key, B., Streiner, D. and McCabe, R., 2017. O-GYN-MD-054 Cognitive Behaviour Therapy for Menopausal Symptoms (CBT-MENO): Preliminary Results from a Randomized Controlled Trial (RCT)–A Mid-Way, Interim Analysis. Journal of Obstetrics and Gynaecology Canada, 39(5), p.388.

Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

2016. Syan, S.K., Steiner, M., Mahoney, J.L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Minuzzi, L., 2016, December. Resting-state fMRI after Acute Tryptophan Depletion in Perimenopause Women on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1400-1400).

2016. Mahoney, J.L., Minuzzi, L., Fedorkow, D., Costescu-Green, D., Hall, G., Frey, B., Soares, C. and Steiner, M., 2016, December. Impact of Tryptophan Depletion on Sleep Efficiency during the Menopausal Transition while on Estrogen Therapy: Preliminary Results. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1394-1395).

Dama, M., Mahoney, J.L., Macdougall, M., Minuzzi, L., Hall, G., Fedorkow, D., Costescu-Green, D., Frey, B., Soares, C. and Steiner, M., 2016, December. Validation of the Menopause Visual Analogue Scale in Determining Mood and Physical Symptoms of Perimenopausal Women on Estrogen Treatment. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (Vol. 23, No. 12, pp. 1395-1395).

Fedorkow, D.M., 2015. Review: In peri-or postmenopausal women, DHEA does not improve symptoms and increases androgenic side effects. Annals of internal medicine, 162(10), pp.JC9-JC9.

Fedorkow, D., 2011. Annual screening with CA-125 and transvaginal ultrasonography did not reduce ovarian cancer incidence or mortality. Annals of internal medicine, 155(6), pp.JC3-8.

Fedorkow D., 2011. Hormone therapy increased risk for kidney stones in healthy postmenopausal women. Annals of Internal Medicine. 154:JC3-10. doi: 10.7326/0003-4819-154-6-201103150-02010

Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.

BIO

After earning her BSc with distinction at the University of Western Ontario in 1998, Dr. Nirupa Gangam began medical school at Queen’s University. In 2002, she entered a residency in obstetrics and gynecology at McMaster University and in 2008 she completed a clinical scholarship in obstetrical and gynecological ultrasound.

Dr. Gangam is currently an assistant professor in the Department of Obstetrics & Gynecology at McMaster University, active staff at St. Joseph’s Hospital and a member of the Gynecologic Quality of Care Committee at St. Joseph’s Hospital in Hamilton.

PUBLICATIONS

Gangam, N. and Kanee, A., 2007. Retroperitoneal hemorrhage after a vaginal mesh prolapse procedure. Obstetrics & Gynecology, 110(2, Part 2), pp.463-464.

BIO

After earning her BSc with distinction at the University of Western Ontario in 1998, Dr. Nirupa Gangam began medical school at Queen’s University. In 2002, she entered a residency in obstetrics and gynecology at McMaster University and in 2008 she completed a clinical scholarship in obstetrical and gynecological ultrasound.

Dr. Gangam is currently an assistant professor in the Department of Obstetrics & Gynecology at McMaster University, active staff at St. Joseph’s Hospital and a member of the Gynecologic Quality of Care Committee at St. Joseph’s Hospital in Hamilton.

PUBLICATIONS

Gangam, N. and Kanee, A., 2007. Retroperitoneal hemorrhage after a vaginal mesh prolapse procedure. Obstetrics & Gynecology, 110(2, Part 2), pp.463-464.

BIO

Dr. Aseel Hamoudi is an academic generalist in the Department of Obstetrics& Gynecology at McMaster University. Dr. Hamoudi completed medical school in Iraq and did her residency in obstetrics and gynecology at the University of Toronto. She also completed a fellowship in high risk obstetrics from the University of Toronto and a masters in health science education from McMaster University.

Dr. Hamoudi’s clinical practice focuses on General OB/Gyn complaints and colposcopy. Dr. Hamoudi is the current Medical Foundation 3 (MF3) subunit planner at McMaster Medical School.

RESEARCH

Research Themes

Colposcopy; High risk obstetrics; Education; Menopause

PUBLICATIONS

Hamoudi, A. and Shier, M., 2010. Late complications of childhood female genital mutilation. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.587-589.

BIO

Dr. Aseel Hamoudi is an academic generalist in the Department of Obstetrics& Gynecology at McMaster University. Dr. Hamoudi completed medical school in Iraq and did her residency in obstetrics and gynecology at the University of Toronto. She also completed a fellowship in high risk obstetrics from the University of Toronto and a masters in health science education from McMaster University.

Dr. Hamoudi’s clinical practice focuses on General OB/Gyn complaints and colposcopy. Dr. Hamoudi is the current Medical Foundation 3 (MF3) subunit planner at McMaster Medical School.

RESEARCH

Research Themes

Colposcopy; High risk obstetrics; Education; Menopause

PUBLICATIONS

Hamoudi, A. and Shier, M., 2010. Late complications of childhood female genital mutilation. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.587-589.

BIO

Dr. Holloway received her PhD in zoology from the University of Guelph in 1997, followed by a post-doctoral fellowship with Dr. John Challis at the University of Toronto. She then moved to McMaster University in 2001, and is currently a professor in the Department of Obstetrics & Gynecology. Her laboratory studies how exposure to chemical insults during pregnancy can lead to metabolic deficits in the offspring and the mechanisms underlying these effects. The chemicals that are of interest to her laboratory include pharmaceuticals, chemicals we may intentionally expose ourselves to through lifestyle choices such as cigarette smoking and man-made chemicals present in the environment. She is funded by Canadian Institutes of Health Research (CIHR) and Natural Sciences and Engineering Research Council of Canada (NSERC).

RESEARCH INTERESTS

Concerns about the impact of chemical toxicants in the environment on animal and human health are increasing globally. While there is a growing perception that these chemical insults adversely affect the health of animal and human populations, there is still little information regarding the mechanisms underlying their actions. To date, research attention has focused largely on adverse reproductive effects following exposure to environmental contaminants with estrogenic activity and has, for the most part, not examined other endocrine or metabolic outcomes. However, it has been suggested that exposure to environmental contaminants may also have an important role in the etiology of metabolic disorders including type 2 diabetes and obesity.

The overall goal of my research program is to understand the mechanism(s) by which chemical insults can cause metabolic endocrine disruption in animal and human populations. In particular, I am interested in determining how fetal exposure to chemical insults results in adverse postnatal health outcomes in the offspring including type 2 diabetes and obesity. The chemicals that I am interested in studying include: chemicals we may intentionally expose ourselves to through lifestyle choices such as cigarette smoking or the use of over the counter natural health products and man-made chemicals present in the environment and naturally occurring chemicals in our diet (e.g., plant phytoestrogens). To date, the bulk of my research has focused on the long-term health consequences of fetal and neonatal exposure to constituents of cigarette smoke and smoking cessation pharmacotherapies. Specifically, we have been examining the mechanisms by which fetal and neonatal exposure to nicotine, as delivered by maternal smoking or nicotine replacement therapy use can result in pancreatic beta cell damage at birth and the development of type 2 diabetes in the adult offspring. My laboratory is also investigating the consequences of fetal exposure to over the counter natural health products, psychiatric medications and man-made chemicals present in the environment on the development of metabolic disorders in adulthood.

Research Themes

Early origins of disease; Fetal toxicology, Smoking, Dysmetabolism; Antidepressant use during pregnancy; pancreas development; Environmental contaminants; Endocrine disruption

PUBLICATIONS

Tung EWY, A Kawata, M Rigde, WJ Bowers, D Caldwell, AC Holloway, B Robaire, BF Hales and MG Wade. 2017. Gestational and lactational exposure to an environmentally-relevant mixture of brominated flame retardants: Effects on neurodevelopment and metabolism. Birth Defects Res 109: 497-512.

Barra NG, M Lisyansky, TA VanDuzer, S Raha, AC Holloway and DB Hardy. Maternal nicotine exposure leads to decreased cardiac protein disulfide isomerase and mitochondrial function in male rat offspring.  J Appl Tox (JAT-17-0143 Accepted in press).

De Long NE, DB Hardy, N Ma and AC Holloway. Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis. J Appl Tox (JAT-17-0201 Accepted in press).

De Long, N.E. and Holloway, A.C., 2017. Early-life chemical exposures and risk of metabolic syndrome. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 10, p.101.

Auerbach, S., Filer, D., Reif, D., Walker, V., Holloway, A.C., Schlezinger, J., Srinivasan, S., Svoboda, D., Judson, R., Bucher, J.R. and Thayer, K.A., 2016. Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCast™ high-throughput data. Environmental health perspectives, 124(8), p.1141.

Reynolds, J.N., Dobson, C.C., Brien, D.C., Holloway, A.C. and Brien, J.F., 2016, June. Prenatal alcohol exposure increases adiposity, disrupts pancreatic morphology and alters expression of insulin signaling molecules in the guinea pig. Alcoholism – Clinical and Experimental Research (Vol. 40, pp. 310A-310A).

Sanches, J.R., França, L.M., Chagas, V.T., Gaspar, R.S., dos Santos, K.A., Gonçalves, L.M., Sloboda, D.M., Holloway, A.C., Dutra, R.P., Carneiro, E.M. and Cappelli, A.P.G., 2016. Polyphenol-rich extract of Syzygium cumini leaf dually improves peripheral insulin sensitivity and pancreatic islet function in monosodium l-glutamate-induced obese rats. Frontiers in pharmacology, 7

Thomson, E.M., Pal, S., Guénette, J., Wade, M.G., Atlas, E., Holloway, A.C., Williams, A. and Vincent, R., 2016. Ozone inhalation provokes glucocorticoid-dependent and-independent effects on inflammatory and metabolic pathways. Toxicological Sciences, 152(1), pp.17-28.

Wong, M.K., Holloway, A.C. and Hardy, D.B., 2016. Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells. Toxicological Sciences, p.kfw019.

Morgan RL, KA Thayer, L Bero, N Bruce, Y Falck-Ytter, D Ghersi, G Guyatt, C Hooijmans, M Langendam, D Mandrioli, RA Mustafa, EA Rehfuess , AA Rooney, B Shea, EK Silbergeld, P Sutton, MS Wolfe, TJ Woodruff, JH Verbeek, AC Holloway , N Santesso and HJ Schünemann. 2016. GRADE: Assessing the quality of evidence in environmental and occupational health. Environ Int 92-93: 611-616.

Akioyamen, L.E., Minhas, H., Holloway, A.C., Taylor, V.H., Akioyamen, N.O. and Sherifali, D., 2016. Effects of depression pharmacotherapy in fertility treatment on conception, birth, and neonatal health: A systematic review. Journal of psychosomatic research, 84, pp.69-80.

Simioni, J., Hutton, E.K., Gunn, E., Holloway, A.C., Stearns, J.C., McDonald, H., Mousseau, A., Schertzer, J.D., Ratcliffe, E.M., Thabane, L. and Surette, M.G., 2016. A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol. BMC pediatrics, 16(1), p.183.

Chaiton, M. and Holloway, A., 2016. Population attributable risk of smoking during pregnancy on obesity in offspring. Can J Public Health, 107(3), p.336.

Avila, C., Holloway, A.C., Hahn, M.K., Morrison, K.M., Restivo, M., Anglin, R. and Taylor, V.H., 2015. An overview of links between obesity and mental health. Current obesity reports, 4(3), pp.303-310.

Pereira, R.D., De Long, N.E., Wang, R.C., Yazdi, F.T., Holloway, A.C. and Raha, S., 2015. Angiogenesis in the placenta: the role of reactive oxygen species signaling. BioMed research international, article 814543.

Nicole, E., Barry, E.J., Pinelli, C., Wood, G.A., Hardy, D.B., Morrison, K.M., Taylor, V.H., Gerstein, H.C. and Holloway, A.C., 2015. Antenatal exposure to the selective serotonin reuptake inhibitor fluoxetine leads to postnatal metabolic and endocrine changes associated with type 2 diabetes in Wistar rats. Toxicology and applied pharmacology, 285(1), pp.32-40.

De Long, N.E., Gutgesell, M.K., Petrik, J.J. and Holloway, A.C., 2015. Fetal Exposure to Sertraline Hydrochloride Impairs Pancreatic ?-Cell Development. Endocrinology, 156(6), pp.1952-1957.

Wong, M.K., Barra, N.G., Alfaidy, N., Hardy, D.B. and Holloway, A.C., 2015. Adverse effects of perinatal nicotine exposure on reproductive outcomes. Reproduction, 150(6), pp.R185-R193.

De Long NE, RA Stepita, VH Taylor and AC Holloway. 2015. Major depressive disorder and diabetes: does serotonin bridge the gap? Curr Diabetes Rev 11: 71-78.

Moore, C.J., DeLong, N.E., Chan, K.A., Holloway, A.C. and Petrik, J.J., 2015. Perinatal administration of a selective serotonin reuptake inhibitor induces impairments in reproductive function and follicular dynamics in female rat offspring. Reproductive sciences, pp.1-15.

Tessier, D.R., Raha, S., Holloway, A.C., Yockell-Lelièvre, J., Tayade, C. and Gruslin, A., 2015. Characterization of immune cells and cytokine localization in the rat utero-placental unit mid-to late gestation. Journal of reproductive immunology, 110, pp.89-101.

Moore, C.J., DeLong, N.E., Chan, K.A., Holloway, A.C. and Sloboda, D.M., 2014, March. Perinatal Exposure to a Selective Serotonin Reuptake Inhibitor (SSRI) Induces Changes in Reproductive Function in Female Rat Offspring. Reproductive Sciences (Vol. 21, No. 3, pp. 271A-271A).

Nguyen, P.V., Ashkar, A.A., Holloway, A.C. and Kaushic, C., 2014. Increased susceptibility to primary Hsv-2 infection during early gestation leads to implantation failure and adverse pregnancy outcome in a mouse model. American Journal of Reproductive Immunology, 71, pp.71-72.

De Long, N.E., Barra, N.G., Hardy, D.B. and Holloway, A.C., 2014. Is it safe to use smoking cessation therapeutics during pregnancy? Expert opinion on drug safety, 13(12), pp.1721-1731.

Holloway, A.C., Salomon, A., Soares, M.J., Garnier, V., Raha, S., Sergent, F., Nicholson, C.J., Feige, J.J., Benharouga, M. and Alfaidy, N., 2014. Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies. American Journal of Physiology-Endocrinology and Metabolism, 306(4), pp.E443-E456.

De Long, N.E., Barry, E., Pinelli, C., Wood, G., Hardy, D.B., Morrison, K.M., Taylor, V.H., Gerstein, H.C. and Holloway, A.C., 2014. Perinatal Exposure to the Selective Serotonin Reuptake Inhibitor Fluoxetine Results in Hepatic Lipid Accumulation and Inflammation. In Obesity and Inflammation (pp. SUN-0910). Endocrine Society.

Salman, S., Holloway, A.C. and Nurse, C.A., 2014. Chronic opioids regulate KATP channel subunit Kir6. 2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2? and protein kinase A. American Journal of Physiology-Cell Physiology, 307(3), pp.C266-C277.

Barra, N.G., Palanivel, R., Denou, E., Chew, M.V., Gillgrass, A., Walker, T.D., Kong, J., Richards, C.D., Jordana, M., Collins, S.M. and Trigatti, B.L., 2014. Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. PloS one, 9(12), p.e114799.

Hayes, E.K., Tessier, D.R., Percival, M.E., Holloway, A.C., Petrik, J.J., Gruslin, A. and Raha, S., 2014. Trophoblast invasion and blood vessel remodeling are altered in a rat model of lifelong maternal obesity. Reproductive Sciences, 21(5), pp.648-657.

Tessier, D.R., Yockell-Lelievre, J., Raha, S., Holloway, A. and Gruslin, A., 2014, March. Maternal Obesity Influences Uterine Immune Response and Trophoblast Invasion. Reproductive Sciences (Vol. 21, No. 3, pp. 380A-380A).

McNulty, J., Keskar, K., Crankshaw, D.J. and Holloway, A.C., 2014. Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic & medicinal chemistry letters, 24(18), pp.4586-4589.

De Long, N.E., Hyslop, J.R., Raha, S., Hardy, D.B. and Holloway, A.C., 2014. Fluoxetine-induced pancreatic beta cell dysfunction: New insight into the benefits of folic acid in the treatment of depression. Journal of affective disorders, 166, pp.6-13.

Dobson, C.C., Thevasundaram, K., Mongillo, D.L., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2014. Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring. Alcohol, 48(7), pp.687-693.

Dobson, C.C., Thevasundaram, K., Mongillo, D., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2014. Chronic Prenatal Ethanol Exposure Alters Insulin And Insulin-like Growth Factor Signaling In The Adult Guinea Pig. Alcoholism: Clinical & Experimental Research, 38, p.260A.

Ma, N., Nicholson, C.J., Wong, M., Holloway, A.C. and Hardy, D.B., 2014. Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase. Toxicology and applied pharmacology, 275(1), pp.1-11.

McNulty, J., Nielsen, A.J., Brown, C.E., DiFrancesco, B.R., Vurgun, N., Nair, J.J., Crankshaw, D.J. and Holloway, A.C., 2013. Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 23(22), pp.6060-6063.

Crankshaw, D.J., Pistilli, M.J., O’Brien, Y.M., Sweeney, E.M., Dockery, P., Holloway, A.C. and Morrison, J.J., 2013. The effects of extracellular calcium-sensing receptor ligands on the contractility of pregnant human myometrium in vitro. Reproductive sciences, p.1933719112468949.

De Long, N., Hyslop, J.R., Nicholson, C.J., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2013. Postnatal metabolic and reproductive consequences of fetal and neonatal exposure to the smoking cessation drug bupropion. Reproductive Sciences, 20(10), pp.1156-1161.

Holloway, A., Salomon, A., Raha, S., Sergent, M.F., Nicholson, C.J., Feige, J.J., Benharouga, M. and Alfaidy, N., 2013. Effet de l’exposition à la nicotine sur le développement placentaire: étude in vivo et in vitro. Annales d’Endocrinologie (Vol. 74, No. 4, pp. 262-263).

Behl, M., Rao, D., Aagaard, K., Davidson, T.L., Levin, E.D., Slotkin, T.A., Srinivasan, S., Wallinga, D., White, M.F., Walker, V.R. and Thayer, K.A., 2013. Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review. Environmental Health Perspectives (Online), 121(2), p.170.

Badv, M., Hosseini, Z., De Long, N., Holloway, A. and Wohl, G., 2013, February. Fetal Exposure to Selective Serotonin Reuptake Inhibitors has Long-Term Adverse Effect on Bone Properties in Rats. Journal of Bone and Mineral Research (Vol. 28).

Ma, N.L., Wong, M., Nicholson, C.J., Holloway, A.C. and Hardy, D.B., 2013, March. Maternal Nicotine Exposure Leads to Elevated Triglycerides in Adult Rat Offspring: The Role of the Liver X Receptor (LXR alpha). Reproductive Sciences (Vol. 20, No. S 3, pp. 279A-279A).

Barra, N.G., Chew, M.V., Holloway, A.C. and Ashkar, A.A., 2012. Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice. Diabetes, Obesity and Metabolism, 14(2), pp.190-193.

Lopez-Yarto, M., Ruiz-Mirazo, E., Holloway, A.C., Taylor, V.H. and McDonald, S.D., 2012. Do psychiatric medications, especially antidepressants, adversely impact maternal metabolic outcomes? Journal of affective disorders, 141(2), pp.120-129.

Dobson, C.C., Mongillo, D.L., Brien, D.C., Stepita, R., Poklewska-Koziell, M., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2012. Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring. Nutrition & diabetes, 2(12), p.e57.

Hayes, E.K., Lechowicz, A., Petrik, J.J., Storozhuk, Y., Paez-Parent, S., Dai, Q., Samjoo, I.A., Mansell, M., Gruslin, A., Holloway, A.C. and Raha, S., 2012. Adverse fetal and neonatal outcomes associated with a life-long high fat diet: role of altered development of the placental vasculature. PLoS One, 7(3), p.e33370.

Woynillowicz, A.K., Raha, S., Nicholson, C.J. and Holloway, A.C., 2012. The effect of smoking cessation pharmacotherapies on pancreatic beta cell function. Toxicology and applied pharmacology, 265(1), pp.122-127.

Bruin, J.E., Woynillowicz, A.K., Hettinga, B.P., Tarnopolsky, M.A., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2012. Maternal antioxidants prevent ?-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure. Journal of diabetes, 4(3), pp.297-306.

Pistilli, M.J., Petrik, J.J., Holloway, A.C. and Crankshaw, D.J., 2012. Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology, 39(1), pp.37-42.

De Long, N.E., Stepita, R.A., Taylor, V.H., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2012, March. Fetal Exposure to the Selective Serotonin Reuptake Inhibitor Sertraline Results in Impaired Fetal Growth and Pancreatic Development in Wistar Rats. Reproductive Sciences (Vol. 19, No. S 3, pp. 119A-119A).

McNulty, J., Nair, J.J., Vurgun, N., DiFrancesco, B.R., Brown, C.E., Tsoi, B., Crankshaw, D.J. and Holloway, A.C., 2012. Discovery of a novel class of aldol-derived 1, 2, 3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 22(1), pp.718-722.

Raha, S., Taylor, V.H. and Holloway, A.C., 2012. Effect of atypical antipsychotics on fetal growth: is the placenta involved? Journal of pregnancy, 2012.

BIO

Dr. Holloway received her PhD in zoology from the University of Guelph in 1997, followed by a post-doctoral fellowship with Dr. John Challis at the University of Toronto. She then moved to McMaster University in 2001, and is currently a professor in the Department of Obstetrics & Gynecology. Her laboratory studies how exposure to chemical insults during pregnancy can lead to metabolic deficits in the offspring and the mechanisms underlying these effects. The chemicals that are of interest to her laboratory include pharmaceuticals, chemicals we may intentionally expose ourselves to through lifestyle choices such as cigarette smoking and man-made chemicals present in the environment. She is funded by Canadian Institutes of Health Research (CIHR) and Natural Sciences and Engineering Research Council of Canada (NSERC).

RESEARCH INTERESTS

Concerns about the impact of chemical toxicants in the environment on animal and human health are increasing globally. While there is a growing perception that these chemical insults adversely affect the health of animal and human populations, there is still little information regarding the mechanisms underlying their actions. To date, research attention has focused largely on adverse reproductive effects following exposure to environmental contaminants with estrogenic activity and has, for the most part, not examined other endocrine or metabolic outcomes. However, it has been suggested that exposure to environmental contaminants may also have an important role in the etiology of metabolic disorders including type 2 diabetes and obesity.

The overall goal of my research program is to understand the mechanism(s) by which chemical insults can cause metabolic endocrine disruption in animal and human populations. In particular, I am interested in determining how fetal exposure to chemical insults results in adverse postnatal health outcomes in the offspring including type 2 diabetes and obesity. The chemicals that I am interested in studying include: chemicals we may intentionally expose ourselves to through lifestyle choices such as cigarette smoking or the use of over the counter natural health products and man-made chemicals present in the environment and naturally occurring chemicals in our diet (e.g., plant phytoestrogens). To date, the bulk of my research has focused on the long-term health consequences of fetal and neonatal exposure to constituents of cigarette smoke and smoking cessation pharmacotherapies. Specifically, we have been examining the mechanisms by which fetal and neonatal exposure to nicotine, as delivered by maternal smoking or nicotine replacement therapy use can result in pancreatic beta cell damage at birth and the development of type 2 diabetes in the adult offspring. My laboratory is also investigating the consequences of fetal exposure to over the counter natural health products, psychiatric medications and man-made chemicals present in the environment on the development of metabolic disorders in adulthood.

Research Themes

Early origins of disease; Fetal toxicology, Smoking, Dysmetabolism; Antidepressant use during pregnancy; pancreas development; Environmental contaminants; Endocrine disruption

PUBLICATIONS

Tung EWY, A Kawata, M Rigde, WJ Bowers, D Caldwell, AC Holloway, B Robaire, BF Hales and MG Wade. 2017. Gestational and lactational exposure to an environmentally-relevant mixture of brominated flame retardants: Effects on neurodevelopment and metabolism. Birth Defects Res 109: 497-512.

Barra NG, M Lisyansky, TA VanDuzer, S Raha, AC Holloway and DB Hardy. Maternal nicotine exposure leads to decreased cardiac protein disulfide isomerase and mitochondrial function in male rat offspring.  J Appl Tox (JAT-17-0143 Accepted in press).

De Long NE, DB Hardy, N Ma and AC Holloway. Increased incidence of non-alcoholic fatty liver disease in male rat offspring exposed to fluoxetine during fetal and neonatal life involves the NLRP3 inflammasome and augmented de novo hepatic lipogenesis. J Appl Tox (JAT-17-0201 Accepted in press).

De Long, N.E. and Holloway, A.C., 2017. Early-life chemical exposures and risk of metabolic syndrome. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 10, p.101.

Auerbach, S., Filer, D., Reif, D., Walker, V., Holloway, A.C., Schlezinger, J., Srinivasan, S., Svoboda, D., Judson, R., Bucher, J.R. and Thayer, K.A., 2016. Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCast™ high-throughput data. Environmental health perspectives, 124(8), p.1141.

Reynolds, J.N., Dobson, C.C., Brien, D.C., Holloway, A.C. and Brien, J.F., 2016, June. Prenatal alcohol exposure increases adiposity, disrupts pancreatic morphology and alters expression of insulin signaling molecules in the guinea pig. Alcoholism – Clinical and Experimental Research (Vol. 40, pp. 310A-310A).

Sanches, J.R., França, L.M., Chagas, V.T., Gaspar, R.S., dos Santos, K.A., Gonçalves, L.M., Sloboda, D.M., Holloway, A.C., Dutra, R.P., Carneiro, E.M. and Cappelli, A.P.G., 2016. Polyphenol-rich extract of Syzygium cumini leaf dually improves peripheral insulin sensitivity and pancreatic islet function in monosodium l-glutamate-induced obese rats. Frontiers in pharmacology, 7

Thomson, E.M., Pal, S., Guénette, J., Wade, M.G., Atlas, E., Holloway, A.C., Williams, A. and Vincent, R., 2016. Ozone inhalation provokes glucocorticoid-dependent and-independent effects on inflammatory and metabolic pathways. Toxicological Sciences, 152(1), pp.17-28.

Wong, M.K., Holloway, A.C. and Hardy, D.B., 2016. Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells. Toxicological Sciences, p.kfw019.

Morgan RL, KA Thayer, L Bero, N Bruce, Y Falck-Ytter, D Ghersi, G Guyatt, C Hooijmans, M Langendam, D Mandrioli, RA Mustafa, EA Rehfuess , AA Rooney, B Shea, EK Silbergeld, P Sutton, MS Wolfe, TJ Woodruff, JH Verbeek, AC Holloway , N Santesso and HJ Schünemann. 2016. GRADE: Assessing the quality of evidence in environmental and occupational health. Environ Int 92-93: 611-616.

Akioyamen, L.E., Minhas, H., Holloway, A.C., Taylor, V.H., Akioyamen, N.O. and Sherifali, D., 2016. Effects of depression pharmacotherapy in fertility treatment on conception, birth, and neonatal health: A systematic review. Journal of psychosomatic research, 84, pp.69-80.

Simioni, J., Hutton, E.K., Gunn, E., Holloway, A.C., Stearns, J.C., McDonald, H., Mousseau, A., Schertzer, J.D., Ratcliffe, E.M., Thabane, L. and Surette, M.G., 2016. A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol. BMC pediatrics, 16(1), p.183.

Chaiton, M. and Holloway, A., 2016. Population attributable risk of smoking during pregnancy on obesity in offspring. Can J Public Health, 107(3), p.336.

Avila, C., Holloway, A.C., Hahn, M.K., Morrison, K.M., Restivo, M., Anglin, R. and Taylor, V.H., 2015. An overview of links between obesity and mental health. Current obesity reports, 4(3), pp.303-310.

Pereira, R.D., De Long, N.E., Wang, R.C., Yazdi, F.T., Holloway, A.C. and Raha, S., 2015. Angiogenesis in the placenta: the role of reactive oxygen species signaling. BioMed research international, article 814543.

Nicole, E., Barry, E.J., Pinelli, C., Wood, G.A., Hardy, D.B., Morrison, K.M., Taylor, V.H., Gerstein, H.C. and Holloway, A.C., 2015. Antenatal exposure to the selective serotonin reuptake inhibitor fluoxetine leads to postnatal metabolic and endocrine changes associated with type 2 diabetes in Wistar rats. Toxicology and applied pharmacology, 285(1), pp.32-40.

De Long, N.E., Gutgesell, M.K., Petrik, J.J. and Holloway, A.C., 2015. Fetal Exposure to Sertraline Hydrochloride Impairs Pancreatic ?-Cell Development. Endocrinology, 156(6), pp.1952-1957.

Wong, M.K., Barra, N.G., Alfaidy, N., Hardy, D.B. and Holloway, A.C., 2015. Adverse effects of perinatal nicotine exposure on reproductive outcomes. Reproduction, 150(6), pp.R185-R193.

De Long NE, RA Stepita, VH Taylor and AC Holloway. 2015. Major depressive disorder and diabetes: does serotonin bridge the gap? Curr Diabetes Rev 11: 71-78.

Moore, C.J., DeLong, N.E., Chan, K.A., Holloway, A.C. and Petrik, J.J., 2015. Perinatal administration of a selective serotonin reuptake inhibitor induces impairments in reproductive function and follicular dynamics in female rat offspring. Reproductive sciences, pp.1-15.

Tessier, D.R., Raha, S., Holloway, A.C., Yockell-Lelièvre, J., Tayade, C. and Gruslin, A., 2015. Characterization of immune cells and cytokine localization in the rat utero-placental unit mid-to late gestation. Journal of reproductive immunology, 110, pp.89-101.

Moore, C.J., DeLong, N.E., Chan, K.A., Holloway, A.C. and Sloboda, D.M., 2014, March. Perinatal Exposure to a Selective Serotonin Reuptake Inhibitor (SSRI) Induces Changes in Reproductive Function in Female Rat Offspring. Reproductive Sciences (Vol. 21, No. 3, pp. 271A-271A).

Nguyen, P.V., Ashkar, A.A., Holloway, A.C. and Kaushic, C., 2014. Increased susceptibility to primary Hsv-2 infection during early gestation leads to implantation failure and adverse pregnancy outcome in a mouse model. American Journal of Reproductive Immunology, 71, pp.71-72.

De Long, N.E., Barra, N.G., Hardy, D.B. and Holloway, A.C., 2014. Is it safe to use smoking cessation therapeutics during pregnancy? Expert opinion on drug safety, 13(12), pp.1721-1731.

Holloway, A.C., Salomon, A., Soares, M.J., Garnier, V., Raha, S., Sergent, F., Nicholson, C.J., Feige, J.J., Benharouga, M. and Alfaidy, N., 2014. Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies. American Journal of Physiology-Endocrinology and Metabolism, 306(4), pp.E443-E456.

De Long, N.E., Barry, E., Pinelli, C., Wood, G., Hardy, D.B., Morrison, K.M., Taylor, V.H., Gerstein, H.C. and Holloway, A.C., 2014. Perinatal Exposure to the Selective Serotonin Reuptake Inhibitor Fluoxetine Results in Hepatic Lipid Accumulation and Inflammation. In Obesity and Inflammation (pp. SUN-0910). Endocrine Society.

Salman, S., Holloway, A.C. and Nurse, C.A., 2014. Chronic opioids regulate KATP channel subunit Kir6. 2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2? and protein kinase A. American Journal of Physiology-Cell Physiology, 307(3), pp.C266-C277.

Barra, N.G., Palanivel, R., Denou, E., Chew, M.V., Gillgrass, A., Walker, T.D., Kong, J., Richards, C.D., Jordana, M., Collins, S.M. and Trigatti, B.L., 2014. Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. PloS one, 9(12), p.e114799.

Hayes, E.K., Tessier, D.R., Percival, M.E., Holloway, A.C., Petrik, J.J., Gruslin, A. and Raha, S., 2014. Trophoblast invasion and blood vessel remodeling are altered in a rat model of lifelong maternal obesity. Reproductive Sciences, 21(5), pp.648-657.

Tessier, D.R., Yockell-Lelievre, J., Raha, S., Holloway, A. and Gruslin, A., 2014, March. Maternal Obesity Influences Uterine Immune Response and Trophoblast Invasion. Reproductive Sciences (Vol. 21, No. 3, pp. 380A-380A).

McNulty, J., Keskar, K., Crankshaw, D.J. and Holloway, A.C., 2014. Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1). Bioorganic & medicinal chemistry letters, 24(18), pp.4586-4589.

De Long, N.E., Hyslop, J.R., Raha, S., Hardy, D.B. and Holloway, A.C., 2014. Fluoxetine-induced pancreatic beta cell dysfunction: New insight into the benefits of folic acid in the treatment of depression. Journal of affective disorders, 166, pp.6-13.

Dobson, C.C., Thevasundaram, K., Mongillo, D.L., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2014. Chronic prenatal ethanol exposure alters expression of central and peripheral insulin signaling molecules in adult guinea pig offspring. Alcohol, 48(7), pp.687-693.

Dobson, C.C., Thevasundaram, K., Mongillo, D., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2014. Chronic Prenatal Ethanol Exposure Alters Insulin And Insulin-like Growth Factor Signaling In The Adult Guinea Pig. Alcoholism: Clinical & Experimental Research, 38, p.260A.

Ma, N., Nicholson, C.J., Wong, M., Holloway, A.C. and Hardy, D.B., 2014. Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase. Toxicology and applied pharmacology, 275(1), pp.1-11.

McNulty, J., Nielsen, A.J., Brown, C.E., DiFrancesco, B.R., Vurgun, N., Nair, J.J., Crankshaw, D.J. and Holloway, A.C., 2013. Investigation of aryl halides as ketone bioisosteres: Refinement of potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 23(22), pp.6060-6063.

Crankshaw, D.J., Pistilli, M.J., O’Brien, Y.M., Sweeney, E.M., Dockery, P., Holloway, A.C. and Morrison, J.J., 2013. The effects of extracellular calcium-sensing receptor ligands on the contractility of pregnant human myometrium in vitro. Reproductive sciences, p.1933719112468949.

De Long, N., Hyslop, J.R., Nicholson, C.J., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2013. Postnatal metabolic and reproductive consequences of fetal and neonatal exposure to the smoking cessation drug bupropion. Reproductive Sciences, 20(10), pp.1156-1161.

Holloway, A., Salomon, A., Raha, S., Sergent, M.F., Nicholson, C.J., Feige, J.J., Benharouga, M. and Alfaidy, N., 2013. Effet de l’exposition à la nicotine sur le développement placentaire: étude in vivo et in vitro. Annales d’Endocrinologie (Vol. 74, No. 4, pp. 262-263).

Behl, M., Rao, D., Aagaard, K., Davidson, T.L., Levin, E.D., Slotkin, T.A., Srinivasan, S., Wallinga, D., White, M.F., Walker, V.R. and Thayer, K.A., 2013. Evaluation of the association between maternal smoking, childhood obesity, and metabolic disorders: a national toxicology program workshop review. Environmental Health Perspectives (Online), 121(2), p.170.

Badv, M., Hosseini, Z., De Long, N., Holloway, A. and Wohl, G., 2013, February. Fetal Exposure to Selective Serotonin Reuptake Inhibitors has Long-Term Adverse Effect on Bone Properties in Rats. Journal of Bone and Mineral Research (Vol. 28).

Ma, N.L., Wong, M., Nicholson, C.J., Holloway, A.C. and Hardy, D.B., 2013, March. Maternal Nicotine Exposure Leads to Elevated Triglycerides in Adult Rat Offspring: The Role of the Liver X Receptor (LXR alpha). Reproductive Sciences (Vol. 20, No. S 3, pp. 279A-279A).

Barra, N.G., Chew, M.V., Holloway, A.C. and Ashkar, A.A., 2012. Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice. Diabetes, Obesity and Metabolism, 14(2), pp.190-193.

Lopez-Yarto, M., Ruiz-Mirazo, E., Holloway, A.C., Taylor, V.H. and McDonald, S.D., 2012. Do psychiatric medications, especially antidepressants, adversely impact maternal metabolic outcomes? Journal of affective disorders, 141(2), pp.120-129.

Dobson, C.C., Mongillo, D.L., Brien, D.C., Stepita, R., Poklewska-Koziell, M., Winterborn, A., Holloway, A.C., Brien, J.F. and Reynolds, J.N., 2012. Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring. Nutrition & diabetes, 2(12), p.e57.

Hayes, E.K., Lechowicz, A., Petrik, J.J., Storozhuk, Y., Paez-Parent, S., Dai, Q., Samjoo, I.A., Mansell, M., Gruslin, A., Holloway, A.C. and Raha, S., 2012. Adverse fetal and neonatal outcomes associated with a life-long high fat diet: role of altered development of the placental vasculature. PLoS One, 7(3), p.e33370.

Woynillowicz, A.K., Raha, S., Nicholson, C.J. and Holloway, A.C., 2012. The effect of smoking cessation pharmacotherapies on pancreatic beta cell function. Toxicology and applied pharmacology, 265(1), pp.122-127.

Bruin, J.E., Woynillowicz, A.K., Hettinga, B.P., Tarnopolsky, M.A., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2012. Maternal antioxidants prevent ?-cell apoptosis and promote formation of dual hormone-expressing endocrine cells in male offspring following fetal and neonatal nicotine exposure. Journal of diabetes, 4(3), pp.297-306.

Pistilli, M.J., Petrik, J.J., Holloway, A.C. and Crankshaw, D.J., 2012. Immunohistochemical and functional studies on calcium-sensing receptors in rat uterine smooth muscle. Clinical and Experimental Pharmacology and Physiology, 39(1), pp.37-42.

De Long, N.E., Stepita, R.A., Taylor, V.H., Morrison, K.M., Gerstein, H.C. and Holloway, A.C., 2012, March. Fetal Exposure to the Selective Serotonin Reuptake Inhibitor Sertraline Results in Impaired Fetal Growth and Pancreatic Development in Wistar Rats. Reproductive Sciences (Vol. 19, No. S 3, pp. 119A-119A).

McNulty, J., Nair, J.J., Vurgun, N., DiFrancesco, B.R., Brown, C.E., Tsoi, B., Crankshaw, D.J. and Holloway, A.C., 2012. Discovery of a novel class of aldol-derived 1, 2, 3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). Bioorganic & medicinal chemistry letters, 22(1), pp.718-722.

Raha, S., Taylor, V.H. and Holloway, A.C., 2012. Effect of atypical antipsychotics on fetal growth: is the placenta involved? Journal of pregnancy, 2012.

BIO

Marlene Huggins is an assistant professor in the Department of Obstetrics & Gynecology at McMaster University and a genetic counsellor in OB/Gyn at Hamilton Health Sciences. After completing her BSc in genetics with honours at the University of Western Ontario, she earned a diploma in genetic counselling in 1987 and her MSc in genetic counselling in 1989 at McGill University.

AREAS OF INTEREST

• Genetic counselling
• Prenatal screening and diagnosis
• Patient decision-making

BIO

Marlene Huggins is an assistant professor in the Department of Obstetrics & Gynecology at McMaster University and a genetic counsellor in OB/Gyn at Hamilton Health Sciences. After completing her BSc in genetics with honours at the University of Western Ontario, she earned a diploma in genetic counselling in 1987 and her MSc in genetic counselling in 1989 at McGill University.

AREAS OF INTEREST

• Genetic counselling
• Prenatal screening and diagnosis
• Patient decision-making

BIO

Edward G. Hughes is a professor of obstetrics and gynecology at McMaster University in Hamilton, Ontario, Canada. He is immediate past president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of fertility care.

After receiving an MBChB from the University of Liverpool Medical School, England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. He completed four years of post-fellowship training in reproductive endocrinology and infertility at the University of Ottawa and Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed his masters in clinical epidemiology and biostatistics.

In addition to training as a reproductive endocrine and Infertility specialist, Dr. Hughes has worked as a general practitioner in a remote area of Northern British Columbia, called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.

Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction and the inhibin/TGFß peptide family. He has recently led and completed a multi-centre randomized controlled trial of expectant management versus in vitro fertilization (EMVI). He is currently beginning research work on Art Therapy as a healing tool for women dealing with infertility. Dr. Hughes has lectured on these topics both nationally and internationally.

Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction and Canadian Medical Journal. He is an associate editor of the Journal Human Reproduction Update and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes also sits on the Science Advisory Panel to the Agency for Human Reproduction Canada.

PUBLICATIONS

O’Reilly, D., Bowen, J.M., Perampaladas, K., Qureshi, R., Xie, F. and Hughes, E., 2017. Feasibility of an altruistic sperm donation program in Canada: results from a population-based model. Reproductive Health, 14(1), p.8.

Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2),  pp.e39-e40.

Hughes, E.G., Sawyer, A., DeJean, D. and Adamson, G.D., 2016. Cross-border reproductive care in North America: a pilot study testing a prospective data collection program for in vitro fertilization clinics in Canada and the United States. Fertility and sterility, 105(3), pp.786-790.

Beck, J.I., Boothroyd, C., Proctor, M., Farquhar, C. and Hughes, E., 2016. Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. Cochrane Database of Systematic Reviews, (1), pp.1-44.

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Hughes, E.G., Grantmyre, J. and Zini, A., 2015. An Integrated Approach to Male-Factor Subfertility: Bridging the Gap Between Fertility Specialists Trained in Urology and Gynaecology. Journal of Obstetrics and Gynaecology Canada, 37(3), pp.258-265.

Hughes, E.G., 2015. Singleton birth at term: an old alarm or a new debate?. Human Reproduction, 30(10), pp.2254-2256.

Mohiyiddeen L, Hardiman A., Fitzgerald C., Hughes E., Mol BJ, Johnson N, Watson. (2015) A Tubal Flushing for Subfertility. Cochrane Library.

Hughes, E. and Pierson, R., 2014. Art and Medicine: Hand and Glove. Journal of Obstetrics and Gynaecology Canada, 36(12), p.1136.

Pierson, R. and Hughes, E., 2014. The Birth of Cupid. Journal of Obstetrics and Gynaecology Canada, 36(3), p.280.

Hughes, E. and Pierson, R., 2014. Pregnant woman. Journal of Obstetrics and Gynaecology Canada, 36(4), p.368.

Pierson, R. and Hughes, E., 2014. Placenta Bowl. Journal of Obstetrics and Gynaecology Canada, 36(10), p.944.

Hughes, E. and Pierson, R., 2014. Mother and Child: A Quiet Mystery. Journal of Obstetrics and Gynaecology Canada, 36(9), p.848.

Pierson, R. and Hughes, E., 2014. Moche Pot. Journal of Obstetrics and Gynaecology Canada, 36(7), p.656.

Pierson, R. and Hughes, E., 2014. Medieval Caesarean Section. Journal of Obstetrics and Gynaecology Canada, 36(11), p.1040.

Hughes, E. and Pierson, R., 2014. From Cradle to Grave. Journal of Obstetrics and Gynaecology Canada, 36(8), p.752.

Hughes, E., and Pierson, R., 2014. William Smellie and the macabre side of obstetrical science. Journal of Obstetrics and Gynaecology Canada, 36(6), p.560.

Pierson, R. and Hughes, E., 2014. A new year—an old hope. Journal of Obstetrics and Gynaecology Canada, 36(1), p.96.

Hughes, E. and Pierson, R., 2014. Love Conquers All. Journal of Obstetrics and  Gynaecology Canada, 36(2),  p.192.

Pierson, R. and Hughes, E., 2014. Primitive Passion. Journal of Obstetrics and Gynaecology Canada, 36(5), p.464.

Hughes, E. and Pierson, R., 2013. The Arnolfini Wedding: The World’s Most Famous Phantom Pregnancy. Journal of Obstetrics and Gynaecology Canada, 35(12), p.1152.

Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

Hughes, E. and Pierson, R., 2013. The Birth of Asclepius: A Postmortem Caesarean Like No Other. Journal of Obstetrics and Gynaecology Canada, 35(8), p.768.

Hughes, E. and Pierson, R., 2013. All Things Come From Eggs. Journal of Obstetrics and Gynaecology Canada, 35(1), p.96.

Hughes, E. and Pierson, R., 2013. The Animalcules of Antoni Van Leeuwenhoek. Journal of Obstetrics and Gynaecology Canada, 35(10), p.960.

van den Boogaard, N.M., Bensdorp, A.J., Rengerink, K.O., Barnhart, K., Bhattacharya, S., Custers, I.M., Coutifaris, C., Goverde, A.J., Guzick, D.S., Hughes, E.C. and Factor-Litvak, P., 2013. Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data. Human reproduction update, Jan-  Feb;20(1):141-51.

Pierson, Roger, and FCAHS FEAS. “Motherhood Undone: A Magical Teaching Tool.” Journal of Obstetrics and Gynaecology Canada 35, no. 3 (2013): 288.

Hughes, E. and Pierson, R., 2013. Life on a half-shell. Journal of Obstetrics and Gynaecology Canada, 35(2),   p.192.

Pierson, R. and Hughes, E., 2013. Imagine All the Species. Journal of Obstetrics and Gynaecology Canada, 35(11), p.1056.

Hughes, E. and Pierson, R., 2013. Frieze Frame. Journal of Obstetrics and Gynaecology Canada, 35(7), p.680.

Pierson, R. and Hughes E., 2013. Broken Dreams of Motherhood: Frida’s Pictures of Pain. J Obstet Gynaecol Can, 35(4), p.392.

Hughes, E., and Pierson R., 2013. Art and Reproductive Science: Celebrating a Glorious Marriage. J Obstet Gynaecol Can, 35(1), pp.17-18.

Hughes, E. and Pierson, R., 2013. A Dangerous Journey: Giving Birth in the 1800s. Journal of Obstetrics and Gynaecology Canada, 35(9), p.864.

Pierson, R. and Hughes, E., 2013. Love in Bloom. Journal of Obstetrics and Gynaecology Canada, 35(5), p.488.

Pierson, R. and Hughes, E., 2013. The Birth of Gossip. Journal of Obstetrics and Gynaecology Canada, 35(6), p.584.

Veltman-Verhulst, S.M., Cohlen, B.J., Hughes, E. and Heineman, M.J., 2012. Intra-uterine insemination for unexplained subfertility. Cochran Database Syst Rev. 2012 Sep 12;9

Sadeu, J.C., Doedée, A.M.C.M., Neal, M.S., Hughes, E.G. and Foster, W.G., 2012. Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses. Reproductive biomedicine online, 24(2), pp.174-179.

Shmorgun, D., Claman, P., Gysler, M., Hemmings, R., Cheung, A.P., Goodrow, G.J., Hughes, E.G., Min, J.K., Roberts, J., Senikas, V. and Wong, B.C.M., 2012. The diagnosis and management of ovarian hyperstimulation syndrome. International Journal of Gynecology & Obstetrics, 116(3), pp.268-273.

Hughes, E.G., van Wely, M. and Farquhar, C.M., 2012. Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication. Human Reproduction.  27 (1): 3-5.

Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

Cook, J.L., Collins, J., Buckett, W., Racowsky, C., Hughes, E. and Jarvi, K., 2011. Assisted reproductive technology-related multiple births: Canada in an international context. Journal of Obstetrics and Gynaecology Canada, 33(2), pp.159-167.

Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.

Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.

BIO

Edward G. Hughes is a professor of obstetrics and gynecology at McMaster University in Hamilton, Ontario, Canada. He is immediate past president of the Canadian Fertility and Andrology Society, Canada’s premier organization representing all disciplines in the field of fertility care.

After receiving an MBChB from the University of Liverpool Medical School, England, Dr. Hughes obtained additional education in Leicester, England, and later at the University of Ottawa, Ontario. He completed four years of post-fellowship training in reproductive endocrinology and infertility at the University of Ottawa and Monash University, Melbourne, Australia. Since joining the faculty at McMaster, Dr. Hughes has also completed his masters in clinical epidemiology and biostatistics.

In addition to training as a reproductive endocrine and Infertility specialist, Dr. Hughes has worked as a general practitioner in a remote area of Northern British Columbia, called Bella Bella, at a community hospital run by the United Church of Canada. He has many interests outside medicine, including fine art, windsurfing and skiing. Ed lives in Ancaster, Ontario with his wife (a pediatrician), their three children and many pets.

Dr. Hughes’ research interests include clinical epidemiology, effectiveness of sub-fertility treatments, the effects of smoking, aging and environmental exposures on reproduction and the inhibin/TGFß peptide family. He has recently led and completed a multi-centre randomized controlled trial of expectant management versus in vitro fertilization (EMVI). He is currently beginning research work on Art Therapy as a healing tool for women dealing with infertility. Dr. Hughes has lectured on these topics both nationally and internationally.

Dr. Hughes is a fellow of the Royal College of Physicians and Surgeons of Canada. Author and coauthor of numerous publications, Dr. Hughes’ work has appeared in such journals as The Journal of Clinical Endocrinology and Metabolism, Human Reproduction and Fertility and Sterility. He is a referee for The British Journal of Obstetrics and Gynaecology, Fertility and Sterility, Human Reproduction and Canadian Medical Journal. He is an associate editor of the Journal Human Reproduction Update and a founding editor of The Cochrane Collaboration Sub-Fertility module. Dr Hughes also sits on the Science Advisory Panel to the Agency for Human Reproduction Canada.

PUBLICATIONS

O’Reilly, D., Bowen, J.M., Perampaladas, K., Qureshi, R., Xie, F. and Hughes, E., 2017. Feasibility of an altruistic sperm donation program in Canada: results from a population-based model. Reproductive Health, 14(1), p.8.

Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2),  pp.e39-e40.

Hughes, E.G., Sawyer, A., DeJean, D. and Adamson, G.D., 2016. Cross-border reproductive care in North America: a pilot study testing a prospective data collection program for in vitro fertilization clinics in Canada and the United States. Fertility and sterility, 105(3), pp.786-790.

Beck, J.I., Boothroyd, C., Proctor, M., Farquhar, C. and Hughes, E., 2016. Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation. Cochrane Database of Systematic Reviews, (1), pp.1-44.

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Hughes, E.G., Grantmyre, J. and Zini, A., 2015. An Integrated Approach to Male-Factor Subfertility: Bridging the Gap Between Fertility Specialists Trained in Urology and Gynaecology. Journal of Obstetrics and Gynaecology Canada, 37(3), pp.258-265.

Hughes, E.G., 2015. Singleton birth at term: an old alarm or a new debate?. Human Reproduction, 30(10), pp.2254-2256.

Mohiyiddeen L, Hardiman A., Fitzgerald C., Hughes E., Mol BJ, Johnson N, Watson. (2015) A Tubal Flushing for Subfertility. Cochrane Library.

Hughes, E. and Pierson, R., 2014. Art and Medicine: Hand and Glove. Journal of Obstetrics and Gynaecology Canada, 36(12), p.1136.

Pierson, R. and Hughes, E., 2014. The Birth of Cupid. Journal of Obstetrics and Gynaecology Canada, 36(3), p.280.

Hughes, E. and Pierson, R., 2014. Pregnant woman. Journal of Obstetrics and Gynaecology Canada, 36(4), p.368.

Pierson, R. and Hughes, E., 2014. Placenta Bowl. Journal of Obstetrics and Gynaecology Canada, 36(10), p.944.

Hughes, E. and Pierson, R., 2014. Mother and Child: A Quiet Mystery. Journal of Obstetrics and Gynaecology Canada, 36(9), p.848.

Pierson, R. and Hughes, E., 2014. Moche Pot. Journal of Obstetrics and Gynaecology Canada, 36(7), p.656.

Pierson, R. and Hughes, E., 2014. Medieval Caesarean Section. Journal of Obstetrics and Gynaecology Canada, 36(11), p.1040.

Hughes, E. and Pierson, R., 2014. From Cradle to Grave. Journal of Obstetrics and Gynaecology Canada, 36(8), p.752.

Hughes, E., and Pierson, R., 2014. William Smellie and the macabre side of obstetrical science. Journal of Obstetrics and Gynaecology Canada, 36(6), p.560.

Pierson, R. and Hughes, E., 2014. A new year—an old hope. Journal of Obstetrics and Gynaecology Canada, 36(1), p.96.

Hughes, E. and Pierson, R., 2014. Love Conquers All. Journal of Obstetrics and  Gynaecology Canada, 36(2),  p.192.

Pierson, R. and Hughes, E., 2014. Primitive Passion. Journal of Obstetrics and Gynaecology Canada, 36(5), p.464.

Hughes, E. and Pierson, R., 2013. The Arnolfini Wedding: The World’s Most Famous Phantom Pregnancy. Journal of Obstetrics and Gynaecology Canada, 35(12), p.1152.

Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

Hughes, E. and Pierson, R., 2013. The Birth of Asclepius: A Postmortem Caesarean Like No Other. Journal of Obstetrics and Gynaecology Canada, 35(8), p.768.

Hughes, E. and Pierson, R., 2013. All Things Come From Eggs. Journal of Obstetrics and Gynaecology Canada, 35(1), p.96.

Hughes, E. and Pierson, R., 2013. The Animalcules of Antoni Van Leeuwenhoek. Journal of Obstetrics and Gynaecology Canada, 35(10), p.960.

van den Boogaard, N.M., Bensdorp, A.J., Rengerink, K.O., Barnhart, K., Bhattacharya, S., Custers, I.M., Coutifaris, C., Goverde, A.J., Guzick, D.S., Hughes, E.C. and Factor-Litvak, P., 2013. Prognostic profiles and the effectiveness of assisted conception: secondary analyses of individual patient data. Human reproduction update, Jan-  Feb;20(1):141-51.

Pierson, Roger, and FCAHS FEAS. “Motherhood Undone: A Magical Teaching Tool.” Journal of Obstetrics and Gynaecology Canada 35, no. 3 (2013): 288.

Hughes, E. and Pierson, R., 2013. Life on a half-shell. Journal of Obstetrics and Gynaecology Canada, 35(2),   p.192.

Pierson, R. and Hughes, E., 2013. Imagine All the Species. Journal of Obstetrics and Gynaecology Canada, 35(11), p.1056.

Hughes, E. and Pierson, R., 2013. Frieze Frame. Journal of Obstetrics and Gynaecology Canada, 35(7), p.680.

Pierson, R. and Hughes E., 2013. Broken Dreams of Motherhood: Frida’s Pictures of Pain. J Obstet Gynaecol Can, 35(4), p.392.

Hughes, E., and Pierson R., 2013. Art and Reproductive Science: Celebrating a Glorious Marriage. J Obstet Gynaecol Can, 35(1), pp.17-18.

Hughes, E. and Pierson, R., 2013. A Dangerous Journey: Giving Birth in the 1800s. Journal of Obstetrics and Gynaecology Canada, 35(9), p.864.

Pierson, R. and Hughes, E., 2013. Love in Bloom. Journal of Obstetrics and Gynaecology Canada, 35(5), p.488.

Pierson, R. and Hughes, E., 2013. The Birth of Gossip. Journal of Obstetrics and Gynaecology Canada, 35(6), p.584.

Veltman-Verhulst, S.M., Cohlen, B.J., Hughes, E. and Heineman, M.J., 2012. Intra-uterine insemination for unexplained subfertility. Cochran Database Syst Rev. 2012 Sep 12;9

Sadeu, J.C., Doedée, A.M.C.M., Neal, M.S., Hughes, E.G. and Foster, W.G., 2012. Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses. Reproductive biomedicine online, 24(2), pp.174-179.

Shmorgun, D., Claman, P., Gysler, M., Hemmings, R., Cheung, A.P., Goodrow, G.J., Hughes, E.G., Min, J.K., Roberts, J., Senikas, V. and Wong, B.C.M., 2012. The diagnosis and management of ovarian hyperstimulation syndrome. International Journal of Gynecology & Obstetrics, 116(3), pp.268-273.

Hughes, E.G., van Wely, M. and Farquhar, C.M., 2012. Cochrane reviews in perspective: the importance of appropriate conclusions and timing of publication. Human Reproduction.  27 (1): 3-5.

Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

Cook, J.L., Collins, J., Buckett, W., Racowsky, C., Hughes, E. and Jarvi, K., 2011. Assisted reproductive technology-related multiple births: Canada in an international context. Journal of Obstetrics and Gynaecology Canada, 33(2), pp.159-167.

Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.

Hughes, E., Brown, J., Collins, J.J., Farquhar, C., Fedorkow, D.M. and Vanderkerchove, P., 2007. Ovulation suppression for endometriosis for women with subfertility. The Cochrane Library.

BIO

Eileen Hutton has a BSc in nursing (Queen’s University, 1974), MScN in parent child nursing (University of Toronto, 1985), a certificate in midwifery (Michener Institute of Applied Health Sciences, 1993), and a PhD in clinical epidemiology (University of Toronto, 2003).

Hutton has received numerous academic awards including the Michael Smith Foundation for Health Research, Career Scholar (2004), a Canadian Institutes of Health Research, New Investigator Award (2004) and Canadian Institutes of Health Research, Research Fellowships (1998–2002 and 2002–03). In June 2006, she was presented with the Western Regional Award by the Society of Obstetricians and Gynaecologists of Canada (SOGC) in recognition of her leadership in research and education.

She was an assistant clinical professor in the McMaster University Department of Family Medicine 1993–2003 and 2003–06, an assistant professor at the University of British Columbia in the division of midwifery at the Child and Family Research Institute. She is now a professor in obstetrics and gynecology, and the assistant dean of the Midwifery Education Program. Professor Hutton also served as professor of midwifery sciences at Vrije University, Amsterdam from 2010–15 on part-time secondment.

Hutton has held many positions in local, provincial and national organizations. As an appointed member of the Ontario Midwifery Education Curriculum Design Committee, Hutton was part of the team which made recommendations for the development of the Midwifery Education Program in Ontario and provided the prototype for the University of British Columbia program.

She has been active in the Society of Obstetricians and Gynaecologists of Canada, playing a pivotal role in representing her profession as the first midwife associate member to council and the first midwife on the Advances in Labour and Risk Management (ALARM) committee. She is a past president of the Association of Ontario Midwives, a founder and current co-editor of the Canadian Journal of Midwifery Research and Practice.

Hutton’s clinical experience is in obstetrical nursing and midwifery. Her research interest lies in clinical practice pertaining to normal childbirth with a particular focus on clinical trial methodology, transdisciplinary research and knowledge translation.

RESEARCH

Research Themes

Mode of birth; Twin birth; External cephalic version (breech birth)

PUBLICATIONS

Hutton, E.K., Simioni, J.C., Thabane, L. and Early ECV2 Trial Collaborative Group, 2017. Predictors of success of external cephalic version and cephalic presentation at birth among 1,253 women with non-cephalic presentation using logistic regression and classification tree analyses. Acta obstetricia et gynecologica Scandinavica. (epub ahead of print: doi: 10.1111/aogs.13161)

Warmelink, J.C., de Cock, T.P., Combee, Y., Rongen, M., Wiegers, T.A. and Hutton, E.K., 2017. Student midwives’ perceptions on the organisation of maternity care and alternative maternity care models in the Netherlands-a qualitative study. BMC Pregnancy and Childbirth, 17(1), p.24.

Krueger, S., Simioni, J., Griffith, L. and Hutton, E., 2017. O-OBS/GYN-S-105 Labour Outcomes after Successful External Cephalic Version Compared to Spontaneous Cephalic Version. Journal of Obstetrics and Gynaecology Canada, 39(5), p.394.

Baron, R., Heesterbeek, Q., Manniën, J., Hutton, E.K., Brug, J. and Westerman, M.J., 2017. Exploring health education with midwives, as perceived by pregnant women in primary care: A qualitative study in the Netherlands. Midwifery, 46, pp.37-44.

Poole, K.L., McDonald, S.D., Griffith, L.E. and Hutton, E.K., 2017. Association of external cephalic version before term with late preterm birth. Acta obstetricia et gynecologica Scandinavica. (epub ahead of print: doi: 10.1111/aogs.13153)

Hutton, E., Farmer, M.J. and Carson, G.D., 2016. The roles of multidisciplinary team members in the care of pregnant women. Journal of Obstetrics and Gynaecology Canada, 38(11), pp.1068-1069.

Asztalos, E.V., Hannah, M.E., Hutton, E.K., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A., Joseph, K.S., Ohlsson, A., Ross, S. and Sanchez, J.J., 2016. Twin Birth Study: 2-year neurodevelopmental follow-up of the randomized trial of planned cesarean or planned vaginal delivery for twin pregnancy. American journal of obstetrics and gynecology, 214(3), pp.371-e1.

Hutton, E.K., 2016. The Safety of Home Birth. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.331-336.

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.

Hutton, E.K., 2016. External cepahlic version should be undertaken by midwives. BJOG: An International Journal of Obstetrics & Gynaecology, 123(3), pp.426-426.

Ahmed, R.J., Gafni, A., Hutton, E.K., Hu, Z.J., Pullenayegum, E., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E. and Menzies, J., 2016. The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial) Novelty and Significance. Hypertension, 68(4), pp.1049-1055.

Ahmed, R.J., Gafni, A., Hutton, E.K. and Early ECV2 Trial Collaborative Group, 2016. The Cost Implications in Ontario, Alberta, and British Columbia of Early Versus Delayed External Cephalic Version in the Early External Cephalic Version 2 (EECV2) Trial. Journal of Obstetrics and Gynaecology Canada, 38(3), pp.235-245.

Magee, L.A., von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. The Control of Hypertension In Pregnancy Study (CHIPS) randomized controlled trial–is severe hypertension just an elevated blood pressure?. Hypertension, 68, pp.1153-59.

Magee, L.A., von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. The CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study) Novelty and Significance. Hypertension, 68(5), pp.1153-1159.

Klomp, T., de Jonge, A., Hutton, E.K., Hers, S. and Lagro-Janssen, A.L., 2016. Perceptions of labour pain management of Dutch primary care midwives: a focus group study. BMC pregnancy and childbirth, 16(1), p.6.

Hutton, E., Farmer, M.J. and Carson, G.D., 2016. Les rôles des membres de l’équipe multidisciplinaire dans les soins aux femmes enceintes. Journal of Obstetrics and Gynaecology Canada, 38(11), pp.1070-1071.

Baron, R., te Velde, S.J., Heymans, M.W., Klomp, T., Hutton, E.K. and Brug, J., 2016. The Relationships of Health Behaviour and Psychological Characteristics with Spontaneous Preterm Birth in Nulliparous Women. Maternal and Child Health Journal, pp.1-10.

Martin, L., Gitsels-van der Wal, J.T., Pereboom, M.T., Spelten, E.R., Hutton, E.K. and van Dulmen, S., 2016. Clients’ psychosocial communication and midwives’ verbal and nonverbal communication during prenatal counseling for anomaly screening. Patient education and counseling, 99(1), pp.85-91.

Baas, C.I., Wiegers, T.A., Cock, T.P., Erwich, J.J.H., Spelten, E.R., Boer, M.R. and Hutton, E.K., 2016. Client-Related Factors Associated with a “Less than Good” Experience of Midwifery Care during Childbirth in the Netherlands. Birth, 44(1), pp. 58-67.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. Can adverse maternal and perinatal outcomes be predicted when blood pressure becomes elevated? Secondary analyses from the CHIPS (Control of Hypertension In Pregnancy Study) randomized controlled trial. Acta obstetricia et gynecologica Scandinavica, 95(7), pp.763-776.

Beuckens, A., Rijnders, M., Verburgt-Doeleman, G.H.M., Rijninks-van Driel, G.C., Thorpe, J. and Hutton, E.K., 2015. An observational study of the success and complications of 2546 external cephalic versions in low-risk pregnant women performed by trained midwives. BJOG: An International Journal of Obstetrics & Gynaecology.

Klomp, T., Witteveen, A.B., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2016. A qualitative interview study into experiences of management of labor pain among women in midwife-led care in the Netherlands. Journal of Psychosomatic Obstetrics & Gynecology, pp.1-9.

Simioni, J., Hutton, E.K., Gunn, E., Holloway, A.C., Stearns, J.C., McDonald, H., Mousseau, A., Schertzer, J.D., Ratcliffe, E.M., Thabane, L. and Surette, M.G., 2016. A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol. BMC pediatrics, 16(1), p.183.

Murray-Davis, B., McVittie, J., Barrett, J.F. and Hutton, E.K., 2016. Exploring Women’s Preferences for the Mode of Delivery in Twin Gestations: Results of the Twin Birth Study. Birth, 43(4), pp.285-292.

Vidler, M., Magee, L.A., Von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J. and Gafni, A., 2016. Women’s views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). European Journal of Obstetrics & Gynecology and Reproductive Biology, 206,  pp.105-113.

Murray-Davis, B., McVittie, J., Barrett, J.F. and Hutton, E.K., 2016. Exploring Women’s Preferences for the Mode of Delivery in Twin Gestations: Results of the Twin Birth Study. Birth, 43(4), pp.285-292.

de Jonge, A., de Vries, R., Lagro-Janssen, A.L., Malata, A., Declercq, E., Downe, S. and Hutton, E.K., 2015. The importance of evaluating primary midwifery care for improving the health of women and infants. Frontiers in medicine, 2.

Hutton, E.K., Hannah, M.E., Ross, S., Joseph, K.S., Ohlsson, A., Asztalos, E.V., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A. and Mangoff, K., 2015. Maternal outcomes at 3 months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial. BJOG: An International Journal of Obstetrics & Gynaecology, 122(12), pp.1653-1662.

Monen, L., Kuppens, S.M., Hasaart, T.H., Oosterbaan, H.P., Oei, S.G., Wijnen, H., Hutton, E.K., Vader, H.L. and Pop, V.J., 2015. Maternal thyrotropin is independently related to Small for Gestational Age neonates at term. Clinical endocrinology, 82(2), pp.254-259.

Butler, M.M., Hutton, E.K. and McNiven, P.S., 2016. Midwifery education in Canada. Midwifery, 33, pp.28-30.

Martin, L., Gitsels-van der Wal, J.T., Pereboom, M.T., Spelten, E.R., Hutton, E.K. and van Dulmen, S., 2015. Midwives’ perceptions of communication during videotaped counseling for prenatal anomaly tests: How do they relate to clients’ perceptions and independent observations?. Patient education and counseling, 98(5), pp.588-597.

Hutton, E.K., Cappelletti, A., Reitsma, A.H., Simioni, J., Horne, J., McGregor, C. and Ahmed, R.J., 2015. Outcomes associated with planned place of birth among women with low-risk pregnancies. Canadian Medical Association Journal, pp.cmaj-150564.

Hutton, H.E., McCaul, M.E., Norris, J., Valliant, J.D., Abrefa-Gyan, T. and Chander, G., 2015. Sex-Related Alcohol Expectancies Among African American Women Attending an Urban STI Clinic. Journal of sex research, 52(5),  pp.580-589.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2015. Less-tight versus tight control of hypertension in pregnancy. New England Journal of Medicine, 372(5), pp.407-417.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2015. [59-OR]: The control of hypertension in pregnancy study (CHIPS) randomized controlled trial–Is the type of antihypertensive important?. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health, 5(1), pp.30-31.

Warmelink, J.C., Wiegers, T.A., de Cock, T.P., Spelten, E.R. and Hutton, E.K., 2015. Career plans of primary care midwives in the Netherlands and their intentions to leave the current job. Human resources for health, 13(1), p.29.

Mei-Dan, E., Asztalos, E., Willan, A., Allen, A., Armson, B.A., Gafni, A., Hannah, M., Hutton, E., Joseph, K., Ohlsson, A. and Ross, S., 2015. Twin birth study: incidence of caesarean delivery in induction of twin pregnancies. American Journal of Obstetrics & Gynecology, 212(1), p.S52.

Baas, C.I., Erwich, J.J.H., Wiegers, T.A., Cock, T.P. and Hutton, E.K., 2015. Women’s suggestions for improving midwifery care in the Netherlands. Birth, 42(4), pp.369-378.

Baron, R., Manniën, J., te Velde, S.J., Klomp, T., Hutton, E.K. and Brug, J., 2015. Socio-demographic inequalities across a range of health status indicators and health behaviours among pregnant women in prenatal primary care: a cross-sectional study. BMC pregnancy and childbirth, 15(1), p.261.

Spelten, E.R., Martin, L., Gitsels, J.T., Pereboom, M.T., Hutton, E.K. and van Dulmen, S., 2015. Introducing video recording in primary care midwifery for research purposes: procedure, dataset, and use. Midwifery, 31(1), pp.95-102.

Westerneng, M., de Cock, P., Spelten, E.R., Honig, A. and Hutton, E.K., 2015. Factorial invariance of pregnancy-specific anxiety dimensions across nulliparous and parous pregnant women. Journal of health psychology, 20(2), pp.164-172.

Hutton, E.K., Hofmeyr, G.J. and Dowswell, T., 2015. External cephalic version for breech presentation before term. The Cochrane Library.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J.,  Sanchez, J. and Gafni, A., 2015. Control of Hypertension In Pregnancy Study randomised controlled trial—are the results dependent on the choice of labetalol or methyldopa?. BJOG: An International Journal of Obstetrics &  Gynaecology.

Gitsels-van der Wal, J.T., Martin, L., Manniën, J., Verhoeven, P., Hutton, E.K. and Reinders, H.S., 2015. Antenatal counselling for congenital anomaly tests: Pregnant Muslim Moroccan women’s  preferences. Midwifery, 31(3), pp.e50-e57.

Martin, L., Hutton, E.K., Gitsels-van der Wal, J.T., Spelten, E.R., Kuiper, F., Pereboom, M.T. and van  Dulmen, S., 2015. Antenatal counselling for congenital anomaly tests: An exploratory video-observational study about client–midwife communication. Midwifery, 31(1), pp.37-46.

Warmelink, J.C., Hoijtink, K., Noppers, M., Wiegers, T.A., de Cock, T.P., Klomp, T. and Hutton, E.K., 2015. An explorative study of factors contributing to the job satisfaction of primary care midwives. Midwifery, 31(4), pp.482-488.

Hall, W.A., Hutton, E., Brant, R.F., Collet, J.P., Gregg, K., Saunders, R., Ipsiroglu, O., Gafni, A., Triolet, K., Tse, L. and Bhagat, R., 2015. A randomized controlled trial of an intervention for infants’ behavioral sleep problems. BMC pediatrics, 15(1), p.181.

Gitsels-van der Wal, J.T., Martin, L., Manniën, J., Verhoeven, P., Hutton, E.K. and Reinders, H.S., 2015. A qualitative study on how Muslim women of Moroccan descent approach antenatal anomaly screening. Midwifery, 31(3), pp.e43-e49.

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Ahmed, R., Simioni, J., Dore, S., Marrin, M., DeSantis, J., Leyland, N., Gardosi, J. and Hutton, E., 2015. Learning from Adverse Events in Obstetrics: Is a Standardized Computer Tool an Effective Strategy for Root Cause Analysis?. Journal of Obstetrics and Gynaecology Canada, 37(8), pp.728-735.

Vallee-Pouliot K, Janssen P, Hutton E. Home birth study fails to identify credentials of midwives conducting home birth. Am J Obstet Bynecol. 2015 Feb;212(2):253-4. doi: 10.1016/j.ajob.2014.10.028. Epub 2014 Oct 19.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2015. Do labetalol and methyldopa have different effects on pregnancy outcome? Analysis of data from the Control of Hypertension In Pregnancy Study (CHIPS) trial. BJOG: An International Journal of Obstetrics & Gynaecology.

Reitsma, A., Chu, R., Thorpe, J., McDonald, S., Thabane, L. and Hutton, E., 2014. Accounting for center in the Early External Cephalic Version trials: an empirical comparison of statistical methods to adjust for center in a multicenter trial with binary outcomes. Trials, 15(1), p.377.

Murray-Davis, B., McDonald, H., Rietsma, A., Coubrough, M. and Hutton, E., 2014. Deciding on home or hospital birth: Results of the Ontario choice of birthplace survey. Midwifery, 30(7), pp.869-876.

Hutton, H.E., Chander, G., Green, P.P., Hutsell, C.A., Weingarten, K. and Peterson, K.L., 2014. A novel integration effort to reduce the risk for alcohol-exposed pregnancy among women attending urban STD clinics. Public Health Reports, 129(1_suppl1), pp.56-62.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K., Menzies, J.M., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2014. The Control of Hypertension In Pregnancy Study (CHIPS) randomised controlled trial. Archives of Disease in Childhood-Fetal and Neonatal Edition, 99(Suppl 1), pp.A5-A6.

Pereboom, M.T., Manniën, J., Rours, G.I.J., Spelten, E.R., Hutton, E.K. and Schellevis, F.G., 2014. Chlamydia trachomatis infection during pregnancy: Knowledge, test practices, and attitudes of Dutch midwives. Scandinavian journal of infectious diseases, 46(2), pp.107-113.

Hutton, E.K. and Hall, W., 2014. Psychoeducation for pregnant women with fear of childbirth increases rates of spontaneous vaginal delivery, reduces caesarean rates and improves delivery experience. Evidence-based nursing, 17(4), pp.105-105.

Wiegers, T.A., Warmelink, J.C., Spelten, E.R., Klomp, T. and Hutton, E.K., 2014. Work and workload of Dutch primary care midwives in 2010. Midwifery, 30(9), pp.991-997.

Pereboom, M.T., Manniën, J., van Almkerk, K.D., Spelten, E.R., Gitsels, J.T., Martin, L., Hutton, E.K. and Schellevis, F.G., 2014. What information do Dutch midwives give clients about toxoplasmosis, listeriosis and cytomegalovirus prevention? An exploratory study of videotaped consultations. Patient education and counseling, 96(1), pp.29-35.

Klomp, T., Manniën, J., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2014. What do midwives need to know about approaches of women towards labour pain management? A qualitative interview study into expectations of management of labour pain for pregnant women receiving midwife-led care in the Netherlands. Midwifery, 30(4), pp.432-438.

Barrett, J., Asztalos, E., Willan, A., Mei-Dan, E., Allen, A., Armson, B.A., Gafni, A., Hannah, M., Hutton, E., Joseph, K. and Ohlsson, A., 2014. 578: Twin Birth Study: neonatal and maternal outcomes in induction in twin pregnancies. American Journal of Obstetrics & Gynecology, 210(1), p.S285.

Hutton, E.K. and Thorpe, J., 2014. Consequences of meconium stained amniotic fluid: What does the evidence tell us?. Early human development, 90(7), pp.333-339.

Gitsels-van der Wal, J.T., Manniën, J., Ghaly, M.M., Verhoeven, P.S., Hutton, E.K. and Reinders, H.S., 2014. The role of religion in decision-making on antenatal screening of congenital anomalies: a qualitative study amongst Muslim Turkish origin immigrants. Midwifery, 30(3), pp.297-302.

Heaman, M.I., Sword, W.A., Akhtar-Danesh, N., Bradford, A., Tough, S., Janssen, P.A., Young, D.C., Kingston, D.A., Hutton, E.K. and Helewa, M.E., 2014. Quality of prenatal care questionnaire: instrument development and testing. BMC pregnancy and childbirth, 14(1), p.188.

Hutton, E.K., Reitsma, A., Thorpe, J., Brunton, G. and Kaufman, K., 2014. Protocol: systematic review and meta-analyses of birth outcomes for women who intend at the onset of labour to give birth at home compared to women of low obstetrical risk who intend to give birth in hospital. Systematic reviews, 3(1), p.55.

Gitsels–van der Wal, J.T., Manniën, J., Gitsels, L.A., Reinders, H.S., Verhoeven, P.S., Ghaly, M.M., Klomp, T. and Hutton, E.K., 2014. Prenatal screening for congenital anomalies: exploring midwives’ perceptions of counseling clients with religious backgrounds. BMC pregnancy and childbirth, 14(1), p.237.

Martin, L., Hutton, E.K., Spelten, E.R., Gitsels-van der Wal, J.T. and van Dulmen, S., 2014. Midwives’ views on appropriate antenatal counselling for congenital anomaly tests: Do they match clients’ preferences?. Midwifery, 30(6), pp.600-609.

Pereboom, M.T., Manniën, J., Spelten, E.R., Hutton, E.K. and Schellevis, F.G., 2014. Maternal cytomegalovirus infection prevention: The role of Dutch primary care midwives. Midwifery, 30(12), pp.1196-1201.

Hutton, E.K., Hannah, M.E., Ross, S., Asztalos, E.V., Willan, A.R., Allen, A.C., Armson, A.B., Gafni, A., Joseph, K.S., Ohlsson, A. and Barrett, J.F., 2014, March. Maternal 3 Month Outcomes after Planned Cesarean (CS) vs Planned Vaginal Birth (VB) for Twin Pregnancies: The Twin Birth Study (TBS). Reproductive Sciences (Vol. 21, No. 3,  pp. 284A-284A).

Pereboom, M.T., Spelten, E.R., Manniën, J., Rours, G.I.J., Morré, S.A., Schellevis, F.G. and Hutton, E.K., 2014. Knowledge and acceptability of Chlamydia trachomatis screening among pregnant women and their partners; a cross-sectional study. BMC public health, 14(1), p.704.

Manniën, J., de Jonge, A., Cornel, M.C., Spelten, E. and Hutton, E.K., 2014. Factors associated with not using folic acid supplements preconceptionally. Public health nutrition, 17(10), pp.2344-2350.

Gitsels-van der Wal, J.T., Verhoeven, P.S., Manniën, J., Martin, L., Reinders, H.S., Spelten, E. and Hutton, E.K., 2014. Factors affecting the uptake of prenatal screening tests for congenital anomalies; a multicentre prospective cohort study. BMC pregnancy and childbirth, 14(1), p.264.

Murray-Davis, B., McDonald, H., Rietsma, A., Coubrough, M. and Hutton, E., 2014. Deciding on home or hospital birth: Results of the Ontario choice of birthplace survey. Midwifery, 30(7), pp.869-876.

Barrett, J., Asztalos, E., Willan, A., Hannah, M., Hutton, E., Allen, A., Armson, B.A., Gafni, A., Joseph, K., Ohlsson, A. and Ross, S., 2014. Twin Birth Study: an analysis of the predictors for a successful planned vaginal twin birth. American Journal of Obstetrics & Gynecology, 210(1), p.S293.

Wainman, B., Murray-Davis, B., McDonald, H., Hutton, E., Cheng, E. and Geurts, C., 2013. Pharmacology revealed-an enhanced e-book for midwifery education. The FASEB Journal, 27(1 Supplement), pp.665-6.

Barrett, J., Aztalos, E., Willan, A., Joseph, K., Armson, B.A., Hutton, E., Allen, A., Ohlsson, A., Ross, S., Farrell, S. and Gafni, A., 2013. The Twin Birth Study: a multicenter RCT of planned cesarean section (CS) and planned vaginal birth (VB) for twin pregnancies 320 to 386/7 weeks. American Journal of Obstetrics & Gynecology, 208(1), pp.S4-S5.

Kuppens, S.M., Brugman, A., Hasaart, T.H., Hutton, E.K. and Pop, V.J., 2013. The effect of change in a labour management protocol on caesarean section rate in nulliparous women. Journal of Obstetrics and Gynaecology Canada, 35(6), pp.508-514.

Martin, L., Van Dulmen, S., Spelten, E., De Jonge, A., De Cock, P. and Hutton, E., 2013. Prenatal counseling for congenital anomaly tests: parental preferences and perceptions of midwife performance. Prenatal diagnosis, 33(4), pp.341-353.

Pereboom, M.T., Manniën, J., Spelten, E.R., Schellevis, F.G. and Hutton, E.K., 2013. Observational study to assess pregnant women’s knowledge and behaviour to prevent toxoplasmosis, listeriosis and cytomegalovirus. BMC pregnancy and childbirth, 13(1), p.98.

Kuppens, S.M., Hutton, E.K., Hasaart, T.H., Aichi, N., Wijnen, H.A. and Pop, V.J., 2013. Mode of delivery following successful external cephalic version: comparison with spontaneous cephalic presentations at delivery. Journal of Obstetrics and Gynaecology Canada, 35(10), pp.883-888.

Klomp, T., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2013. Dutch women in midwife-led care at  the onset of labour: which pain relief do they prefer and what do they use?. BMC Pregnancy and childbirth, 13(1),  p.230.

Baas, C., Wiegers, T., de Cock, P., Koelewijn, J. and Hutton, E., 2013. Continuous support during childbirth by maternity care assistants: An exploration of opinions in the Netherlands. International Journal of Childbirth, 3(2),  pp.76-85.

Hutton, E.K., Stoll, K. and Taha, N., 2013. An observational study of umbilical cord clamping practices of maternity care providers in a tertiary care center. Birth, 40(1), pp.39-45.

De Jonge, A., Baron, R., Westerneng, M., Twisk, J. and Hutton, E.K., 2013. Perinatal mortality rate in the Netherlands compared to other European countries: a secondary analysis of Euro-PERISTAT data. Midwifery, 29(8),  pp.1011-1018.

Baron, R., Manniën, J., de Jonge, A., Heymans, M.W., Klomp, T., Hutton, E.K. and Brug, J., 2013. Socio- demographic and lifestyle-related characteristics associated with self-reported any, daily and occasional smoking during pregnancy. PLoS One, 8(9), p.e74197.

Barrett, J.F., Hannah, M.E., Hutton, E.K., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A., Joseph, K.S., Mason, D., Ohlsson, A. and Ross, S., 2013. A randomized trial of planned cesarean or vaginal delivery for twin pregnancy. New England Journal of Medicine, 369(14), pp.1295-1305.

Murray-Davis B, Marion A, Malott A, Reitsma A, Hutton E for the Early ECV2 Trial Collaborative Group. Women’s experiences of participating in the ECV2 Trial. Birth;39(1):1-9. doi: 10.111/j.1523-536X.2011.00510.x. Epub  2012 Jan 9

Murray-Davis, B., McNiven, P., McDonald, H., Malott, A., Elarar, L. and Hutton, E., 2012. Why home birth? A qualitative study exploring women’s decision making about place of birth in two Canadian provinces. Midwifery, 28(5), pp.576-581.

Sword, W., Heaman, M.I., Brooks, S., Tough, S., Janssen, P.A., Young, D., Kingston, D., Helewa, M.E., Akhtar-Danesh, N. and Hutton, E., 2012. Women’s and care providers’ perspectives of quality prenatal care: a qualitative descriptive study. BMC pregnancy and childbirth, 12(1), p.29.

Murray-Davis, B., Marion, A., Malott, A., Reitsma, A. and Hutton, E.K., 2012. Women’s experiences of participating in the early external cephalic version 2 trial. Birth, 39(1), pp.30-38.

Srinivasjois RM, Shah S, Shah PS: Knowledge Synthesis Group on Determinants Of Preterm/LBW Births (including Hutton EK). Biracial couples and adverse birth outcomes: a systematic review and meta-analyses. Acta Obstet Gynecol Scand. 2012 Oct;91(10):1134-46. di: 10.1111/j.1600-0412.2012.01501.x. Epub 2012 Aug 24. Review

De Hundt, M., Vlemmix, F., Bais, J.M.J., Hutton, E.K., De Groot, C.J., Mol, B.W.J. and Kok, M., 2012. Risk factors for developmental dysplasia of the hip: a meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 165(1), pp.8-17.

van Rheenen P, Hutton E Less iron deficiency after late cord clamping. Journal for Midwives.Inst. Rijnstate Hospital, Arnhem, NL. 29-32. December 1, 2012.

McDonald, S.D., Pullenayegum, E., Bracken, K., Chen, A.M., McDonald, H., Malott, A., Hutchison, R., Haley, S., Lutsiv, O., Taylor, V.H. and Good, C., 2012. Comparison of midwifery, family medicine, and obstetric patients’ understanding of weight gain during pregnancy: a minority of women report correct counselling. Journal of Obstetrics and Gynaecology Canada, 34(2), pp.129-135.

Hutton, E.K., Hannah, M.E., Ross, S.J., Delisle, M.F., Carson, G.D., Windrim, R., Ohlsson, A., Willan, A.R., Gafni, A., Sylvestre, G. and Natale, R., 2012. The Early External Cephalic Version 2 Trial: An International Multicenter Randomized-controlled Trial of Timing of ECV for Breech Pregnancies. Obstetric Anesthesia Digest, 32(2), p.128.

Martin, L., Dulmen, S.V., Spelten, E. and Hutton, E., 2012. Prenatal genetic counseling: future parents prefer to make decisions together, using professional advice.  NIVEL – The Netherlands Institute for Health Services Research

Hutton, E.K. and Kornelsen, J., 2012. Patient-Initiated Elective Cesarean Section of Nulliparous Women in British Columbia, Canada. Birth, 39(3), pp.175-182.

Malott, A.M., Kaufman, K., Thorpe, J., Saxell, L., Becker, G., Paulette, L., Ashe, A., Martin, K., Yeates, L. and Hutton, E.K., 2012. Models of organization of maternity care by midwives in Canada: a descriptive review. Journal of Obstetrics and Gynaecology Canada, 34(10), pp.961-970.

Manniën, J., Klomp, T., Wiegers, T., Pereboom, M., Brug, J., de Jonge, A., van der Meijde, M., Hutton, E., Schellevis, F. and Spelten, E., 2012. Evaluation of primary care midwifery in the Netherlands: design and rationale of a dynamic cohort study (DELIVER). BMC health services research, 12(1), p.69.

Kornelsen, J. and Hutton, E., 2012. Attributes and Experiences of Patient-Initiated Elective Cesarean Section. Canadian Journal of Midwifery Research and Practice, 11(1), p.9.

Stoll, K. and Hutton, E., 2012. A Survey of Umbilical Cord Clamping Practices and Attitudes of Canadian Maternity Care Providers-Survol des pratiques en matière de clampage du cordon ombilical et des attitudes des fournisseurs de soins obstétricaux canadiens. Canadian Journal of Midwifery Research and Practice, 11(3), p.18.

Hall, W.A., Stoll, K., Hutton, E.K. and Brown, H., 2012. A prospective study of effects of psychological factors and sleep on obstetric interventions, mode of birth, and neonatal outcomes among low-risk British Columbian women. BMC pregnancy and childbirth, 12(1), p.78.

Spelten, E., Gitsels, J., Pereboom, M., Martin, L., Hutton, E. and Dulmen, S.V., 2012. Video recording to improve the quality of prenatal genetic counselling.  NIVEL – The Netherlands Institute for Health Services Research

McDonald, S.D., Pullenayegum, E., Taylor, V., Lutsiv, O., Bracken, K., Good, C., Hutton, E., Chen, A.M., Hutchison, R., Malott, A. and McDonald, H., 2011. 182-Three-quarters of overweight and obese women are planning on exceeding the gestational weight gain recommendations. Canadian Journal of Diabetes, 35(2), p.187.

McDonald SD, Han Z, Mulla S, Lutisv O, Lee T, Beyene J; Knowledge Synthesis Group. High gestational weight gain and the risk of preterm birth and low birth weight; a systematic review and meta-analysis. J Obstet Gynaecol Can. 2011 Dec;33(12):1223-33

Malott, A.M., Davis, B.M., McDonald, H. and Hutton, E., 2009. Midwifery care in eight industrialized countries: how does Canadian midwifery compare?. Journal of Obstetrics and Gynaecology Canada, 31(10), pp.974-979.

BIO

Eileen Hutton has a BSc in nursing (Queen’s University, 1974), MScN in parent child nursing (University of Toronto, 1985), a certificate in midwifery (Michener Institute of Applied Health Sciences, 1993), and a PhD in clinical epidemiology (University of Toronto, 2003).

Hutton has received numerous academic awards including the Michael Smith Foundation for Health Research, Career Scholar (2004), a Canadian Institutes of Health Research, New Investigator Award (2004) and Canadian Institutes of Health Research, Research Fellowships (1998–2002 and 2002–03). In June 2006, she was presented with the Western Regional Award by the Society of Obstetricians and Gynaecologists of Canada (SOGC) in recognition of her leadership in research and education.

She was an assistant clinical professor in the McMaster University Department of Family Medicine 1993–2003 and 2003–06, an assistant professor at the University of British Columbia in the division of midwifery at the Child and Family Research Institute. She is now a professor in obstetrics and gynecology, and the assistant dean of the Midwifery Education Program. Professor Hutton also served as professor of midwifery sciences at Vrije University, Amsterdam from 2010–15 on part-time secondment.

Hutton has held many positions in local, provincial and national organizations. As an appointed member of the Ontario Midwifery Education Curriculum Design Committee, Hutton was part of the team which made recommendations for the development of the Midwifery Education Program in Ontario and provided the prototype for the University of British Columbia program.

She has been active in the Society of Obstetricians and Gynaecologists of Canada, playing a pivotal role in representing her profession as the first midwife associate member to council and the first midwife on the Advances in Labour and Risk Management (ALARM) committee. She is a past president of the Association of Ontario Midwives, a founder and current co-editor of the Canadian Journal of Midwifery Research and Practice.

Hutton’s clinical experience is in obstetrical nursing and midwifery. Her research interest lies in clinical practice pertaining to normal childbirth with a particular focus on clinical trial methodology, transdisciplinary research and knowledge translation.

RESEARCH

Research Themes

Mode of birth; Twin birth; External cephalic version (breech birth)

PUBLICATIONS

Hutton, E.K., Simioni, J.C., Thabane, L. and Early ECV2 Trial Collaborative Group, 2017. Predictors of success of external cephalic version and cephalic presentation at birth among 1,253 women with non-cephalic presentation using logistic regression and classification tree analyses. Acta obstetricia et gynecologica Scandinavica. (epub ahead of print: doi: 10.1111/aogs.13161)

Warmelink, J.C., de Cock, T.P., Combee, Y., Rongen, M., Wiegers, T.A. and Hutton, E.K., 2017. Student midwives’ perceptions on the organisation of maternity care and alternative maternity care models in the Netherlands-a qualitative study. BMC Pregnancy and Childbirth, 17(1), p.24.

Krueger, S., Simioni, J., Griffith, L. and Hutton, E., 2017. O-OBS/GYN-S-105 Labour Outcomes after Successful External Cephalic Version Compared to Spontaneous Cephalic Version. Journal of Obstetrics and Gynaecology Canada, 39(5), p.394.

Baron, R., Heesterbeek, Q., Manniën, J., Hutton, E.K., Brug, J. and Westerman, M.J., 2017. Exploring health education with midwives, as perceived by pregnant women in primary care: A qualitative study in the Netherlands. Midwifery, 46, pp.37-44.

Poole, K.L., McDonald, S.D., Griffith, L.E. and Hutton, E.K., 2017. Association of external cephalic version before term with late preterm birth. Acta obstetricia et gynecologica Scandinavica. (epub ahead of print: doi: 10.1111/aogs.13153)

Hutton, E., Farmer, M.J. and Carson, G.D., 2016. The roles of multidisciplinary team members in the care of pregnant women. Journal of Obstetrics and Gynaecology Canada, 38(11), pp.1068-1069.

Asztalos, E.V., Hannah, M.E., Hutton, E.K., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A., Joseph, K.S., Ohlsson, A., Ross, S. and Sanchez, J.J., 2016. Twin Birth Study: 2-year neurodevelopmental follow-up of the randomized trial of planned cesarean or planned vaginal delivery for twin pregnancy. American journal of obstetrics and gynecology, 214(3), pp.371-e1.

Hutton, E.K., 2016. The Safety of Home Birth. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.331-336.

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.

Hutton, E.K., 2016. External cepahlic version should be undertaken by midwives. BJOG: An International Journal of Obstetrics & Gynaecology, 123(3), pp.426-426.

Ahmed, R.J., Gafni, A., Hutton, E.K., Hu, Z.J., Pullenayegum, E., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E. and Menzies, J., 2016. The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial) Novelty and Significance. Hypertension, 68(4), pp.1049-1055.

Ahmed, R.J., Gafni, A., Hutton, E.K. and Early ECV2 Trial Collaborative Group, 2016. The Cost Implications in Ontario, Alberta, and British Columbia of Early Versus Delayed External Cephalic Version in the Early External Cephalic Version 2 (EECV2) Trial. Journal of Obstetrics and Gynaecology Canada, 38(3), pp.235-245.

Magee, L.A., von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. The Control of Hypertension In Pregnancy Study (CHIPS) randomized controlled trial–is severe hypertension just an elevated blood pressure?. Hypertension, 68, pp.1153-59.

Magee, L.A., von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. The CHIPS Randomized Controlled Trial (Control of Hypertension in Pregnancy Study) Novelty and Significance. Hypertension, 68(5), pp.1153-1159.

Klomp, T., de Jonge, A., Hutton, E.K., Hers, S. and Lagro-Janssen, A.L., 2016. Perceptions of labour pain management of Dutch primary care midwives: a focus group study. BMC pregnancy and childbirth, 16(1), p.6.

Hutton, E., Farmer, M.J. and Carson, G.D., 2016. Les rôles des membres de l’équipe multidisciplinaire dans les soins aux femmes enceintes. Journal of Obstetrics and Gynaecology Canada, 38(11), pp.1070-1071.

Baron, R., te Velde, S.J., Heymans, M.W., Klomp, T., Hutton, E.K. and Brug, J., 2016. The Relationships of Health Behaviour and Psychological Characteristics with Spontaneous Preterm Birth in Nulliparous Women. Maternal and Child Health Journal, pp.1-10.

Martin, L., Gitsels-van der Wal, J.T., Pereboom, M.T., Spelten, E.R., Hutton, E.K. and van Dulmen, S., 2016. Clients’ psychosocial communication and midwives’ verbal and nonverbal communication during prenatal counseling for anomaly screening. Patient education and counseling, 99(1), pp.85-91.

Baas, C.I., Wiegers, T.A., Cock, T.P., Erwich, J.J.H., Spelten, E.R., Boer, M.R. and Hutton, E.K., 2016. Client-Related Factors Associated with a “Less than Good” Experience of Midwifery Care during Childbirth in the Netherlands. Birth, 44(1), pp. 58-67.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2016. Can adverse maternal and perinatal outcomes be predicted when blood pressure becomes elevated? Secondary analyses from the CHIPS (Control of Hypertension In Pregnancy Study) randomized controlled trial. Acta obstetricia et gynecologica Scandinavica, 95(7), pp.763-776.

Beuckens, A., Rijnders, M., Verburgt-Doeleman, G.H.M., Rijninks-van Driel, G.C., Thorpe, J. and Hutton, E.K., 2015. An observational study of the success and complications of 2546 external cephalic versions in low-risk pregnant women performed by trained midwives. BJOG: An International Journal of Obstetrics & Gynaecology.

Klomp, T., Witteveen, A.B., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2016. A qualitative interview study into experiences of management of labor pain among women in midwife-led care in the Netherlands. Journal of Psychosomatic Obstetrics & Gynecology, pp.1-9.

Simioni, J., Hutton, E.K., Gunn, E., Holloway, A.C., Stearns, J.C., McDonald, H., Mousseau, A., Schertzer, J.D., Ratcliffe, E.M., Thabane, L. and Surette, M.G., 2016. A comparison of intestinal microbiota in a population of low-risk infants exposed and not exposed to intrapartum antibiotics: The Baby & Microbiota of the Intestine cohort study protocol. BMC pediatrics, 16(1), p.183.

Murray-Davis, B., McVittie, J., Barrett, J.F. and Hutton, E.K., 2016. Exploring Women’s Preferences for the Mode of Delivery in Twin Gestations: Results of the Twin Birth Study. Birth, 43(4), pp.285-292.

Vidler, M., Magee, L.A., Von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J. and Gafni, A., 2016. Women’s views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). European Journal of Obstetrics & Gynecology and Reproductive Biology, 206,  pp.105-113.

Murray-Davis, B., McVittie, J., Barrett, J.F. and Hutton, E.K., 2016. Exploring Women’s Preferences for the Mode of Delivery in Twin Gestations: Results of the Twin Birth Study. Birth, 43(4), pp.285-292.

de Jonge, A., de Vries, R., Lagro-Janssen, A.L., Malata, A., Declercq, E., Downe, S. and Hutton, E.K., 2015. The importance of evaluating primary midwifery care for improving the health of women and infants. Frontiers in medicine, 2.

Hutton, E.K., Hannah, M.E., Ross, S., Joseph, K.S., Ohlsson, A., Asztalos, E.V., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A. and Mangoff, K., 2015. Maternal outcomes at 3 months after planned caesarean section versus planned vaginal birth for twin pregnancies in the Twin Birth Study: a randomised controlled trial. BJOG: An International Journal of Obstetrics & Gynaecology, 122(12), pp.1653-1662.

Monen, L., Kuppens, S.M., Hasaart, T.H., Oosterbaan, H.P., Oei, S.G., Wijnen, H., Hutton, E.K., Vader, H.L. and Pop, V.J., 2015. Maternal thyrotropin is independently related to Small for Gestational Age neonates at term. Clinical endocrinology, 82(2), pp.254-259.

Butler, M.M., Hutton, E.K. and McNiven, P.S., 2016. Midwifery education in Canada. Midwifery, 33, pp.28-30.

Martin, L., Gitsels-van der Wal, J.T., Pereboom, M.T., Spelten, E.R., Hutton, E.K. and van Dulmen, S., 2015. Midwives’ perceptions of communication during videotaped counseling for prenatal anomaly tests: How do they relate to clients’ perceptions and independent observations?. Patient education and counseling, 98(5), pp.588-597.

Hutton, E.K., Cappelletti, A., Reitsma, A.H., Simioni, J., Horne, J., McGregor, C. and Ahmed, R.J., 2015. Outcomes associated with planned place of birth among women with low-risk pregnancies. Canadian Medical Association Journal, pp.cmaj-150564.

Hutton, H.E., McCaul, M.E., Norris, J., Valliant, J.D., Abrefa-Gyan, T. and Chander, G., 2015. Sex-Related Alcohol Expectancies Among African American Women Attending an Urban STI Clinic. Journal of sex research, 52(5),  pp.580-589.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2015. Less-tight versus tight control of hypertension in pregnancy. New England Journal of Medicine, 372(5), pp.407-417.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2015. [59-OR]: The control of hypertension in pregnancy study (CHIPS) randomized controlled trial–Is the type of antihypertensive important?. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health, 5(1), pp.30-31.

Warmelink, J.C., Wiegers, T.A., de Cock, T.P., Spelten, E.R. and Hutton, E.K., 2015. Career plans of primary care midwives in the Netherlands and their intentions to leave the current job. Human resources for health, 13(1), p.29.

Mei-Dan, E., Asztalos, E., Willan, A., Allen, A., Armson, B.A., Gafni, A., Hannah, M., Hutton, E., Joseph, K., Ohlsson, A. and Ross, S., 2015. Twin birth study: incidence of caesarean delivery in induction of twin pregnancies. American Journal of Obstetrics & Gynecology, 212(1), p.S52.

Baas, C.I., Erwich, J.J.H., Wiegers, T.A., Cock, T.P. and Hutton, E.K., 2015. Women’s suggestions for improving midwifery care in the Netherlands. Birth, 42(4), pp.369-378.

Baron, R., Manniën, J., te Velde, S.J., Klomp, T., Hutton, E.K. and Brug, J., 2015. Socio-demographic inequalities across a range of health status indicators and health behaviours among pregnant women in prenatal primary care: a cross-sectional study. BMC pregnancy and childbirth, 15(1), p.261.

Spelten, E.R., Martin, L., Gitsels, J.T., Pereboom, M.T., Hutton, E.K. and van Dulmen, S., 2015. Introducing video recording in primary care midwifery for research purposes: procedure, dataset, and use. Midwifery, 31(1), pp.95-102.

Westerneng, M., de Cock, P., Spelten, E.R., Honig, A. and Hutton, E.K., 2015. Factorial invariance of pregnancy-specific anxiety dimensions across nulliparous and parous pregnant women. Journal of health psychology, 20(2), pp.164-172.

Hutton, E.K., Hofmeyr, G.J. and Dowswell, T., 2015. External cephalic version for breech presentation before term. The Cochrane Library.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J.,  Sanchez, J. and Gafni, A., 2015. Control of Hypertension In Pregnancy Study randomised controlled trial—are the results dependent on the choice of labetalol or methyldopa?. BJOG: An International Journal of Obstetrics &  Gynaecology.

Gitsels-van der Wal, J.T., Martin, L., Manniën, J., Verhoeven, P., Hutton, E.K. and Reinders, H.S., 2015. Antenatal counselling for congenital anomaly tests: Pregnant Muslim Moroccan women’s  preferences. Midwifery, 31(3), pp.e50-e57.

Martin, L., Hutton, E.K., Gitsels-van der Wal, J.T., Spelten, E.R., Kuiper, F., Pereboom, M.T. and van  Dulmen, S., 2015. Antenatal counselling for congenital anomaly tests: An exploratory video-observational study about client–midwife communication. Midwifery, 31(1), pp.37-46.

Warmelink, J.C., Hoijtink, K., Noppers, M., Wiegers, T.A., de Cock, T.P., Klomp, T. and Hutton, E.K., 2015. An explorative study of factors contributing to the job satisfaction of primary care midwives. Midwifery, 31(4), pp.482-488.

Hall, W.A., Hutton, E., Brant, R.F., Collet, J.P., Gregg, K., Saunders, R., Ipsiroglu, O., Gafni, A., Triolet, K., Tse, L. and Bhagat, R., 2015. A randomized controlled trial of an intervention for infants’ behavioral sleep problems. BMC pediatrics, 15(1), p.181.

Gitsels-van der Wal, J.T., Martin, L., Manniën, J., Verhoeven, P., Hutton, E.K. and Reinders, H.S., 2015. A qualitative study on how Muslim women of Moroccan descent approach antenatal anomaly screening. Midwifery, 31(3), pp.e43-e49.

Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Ahmed, R., Simioni, J., Dore, S., Marrin, M., DeSantis, J., Leyland, N., Gardosi, J. and Hutton, E., 2015. Learning from Adverse Events in Obstetrics: Is a Standardized Computer Tool an Effective Strategy for Root Cause Analysis?. Journal of Obstetrics and Gynaecology Canada, 37(8), pp.728-735.

Vallee-Pouliot K, Janssen P, Hutton E. Home birth study fails to identify credentials of midwives conducting home birth. Am J Obstet Bynecol. 2015 Feb;212(2):253-4. doi: 10.1016/j.ajob.2014.10.028. Epub 2014 Oct 19.

Magee, L.A., Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., Asztalos, E., Murphy, K.E., Menzies, J., Sanchez, J. and Gafni, A., 2015. Do labetalol and methyldopa have different effects on pregnancy outcome? Analysis of data from the Control of Hypertension In Pregnancy Study (CHIPS) trial. BJOG: An International Journal of Obstetrics & Gynaecology.

Reitsma, A., Chu, R., Thorpe, J., McDonald, S., Thabane, L. and Hutton, E., 2014. Accounting for center in the Early External Cephalic Version trials: an empirical comparison of statistical methods to adjust for center in a multicenter trial with binary outcomes. Trials, 15(1), p.377.

Murray-Davis, B., McDonald, H., Rietsma, A., Coubrough, M. and Hutton, E., 2014. Deciding on home or hospital birth: Results of the Ontario choice of birthplace survey. Midwifery, 30(7), pp.869-876.

Hutton, H.E., Chander, G., Green, P.P., Hutsell, C.A., Weingarten, K. and Peterson, K.L., 2014. A novel integration effort to reduce the risk for alcohol-exposed pregnancy among women attending urban STD clinics. Public Health Reports, 129(1_suppl1), pp.56-62.

Magee, L.A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., Murphy, K., Menzies, J.M., Sanchez, J., Singer, J., Gafni, A. and Gruslin, A., 2014. The Control of Hypertension In Pregnancy Study (CHIPS) randomised controlled trial. Archives of Disease in Childhood-Fetal and Neonatal Edition, 99(Suppl 1), pp.A5-A6.

Pereboom, M.T., Manniën, J., Rours, G.I.J., Spelten, E.R., Hutton, E.K. and Schellevis, F.G., 2014. Chlamydia trachomatis infection during pregnancy: Knowledge, test practices, and attitudes of Dutch midwives. Scandinavian journal of infectious diseases, 46(2), pp.107-113.

Hutton, E.K. and Hall, W., 2014. Psychoeducation for pregnant women with fear of childbirth increases rates of spontaneous vaginal delivery, reduces caesarean rates and improves delivery experience. Evidence-based nursing, 17(4), pp.105-105.

Wiegers, T.A., Warmelink, J.C., Spelten, E.R., Klomp, T. and Hutton, E.K., 2014. Work and workload of Dutch primary care midwives in 2010. Midwifery, 30(9), pp.991-997.

Pereboom, M.T., Manniën, J., van Almkerk, K.D., Spelten, E.R., Gitsels, J.T., Martin, L., Hutton, E.K. and Schellevis, F.G., 2014. What information do Dutch midwives give clients about toxoplasmosis, listeriosis and cytomegalovirus prevention? An exploratory study of videotaped consultations. Patient education and counseling, 96(1), pp.29-35.

Klomp, T., Manniën, J., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2014. What do midwives need to know about approaches of women towards labour pain management? A qualitative interview study into expectations of management of labour pain for pregnant women receiving midwife-led care in the Netherlands. Midwifery, 30(4), pp.432-438.

Barrett, J., Asztalos, E., Willan, A., Mei-Dan, E., Allen, A., Armson, B.A., Gafni, A., Hannah, M., Hutton, E., Joseph, K. and Ohlsson, A., 2014. 578: Twin Birth Study: neonatal and maternal outcomes in induction in twin pregnancies. American Journal of Obstetrics & Gynecology, 210(1), p.S285.

Hutton, E.K. and Thorpe, J., 2014. Consequences of meconium stained amniotic fluid: What does the evidence tell us?. Early human development, 90(7), pp.333-339.

Gitsels-van der Wal, J.T., Manniën, J., Ghaly, M.M., Verhoeven, P.S., Hutton, E.K. and Reinders, H.S., 2014. The role of religion in decision-making on antenatal screening of congenital anomalies: a qualitative study amongst Muslim Turkish origin immigrants. Midwifery, 30(3), pp.297-302.

Heaman, M.I., Sword, W.A., Akhtar-Danesh, N., Bradford, A., Tough, S., Janssen, P.A., Young, D.C., Kingston, D.A., Hutton, E.K. and Helewa, M.E., 2014. Quality of prenatal care questionnaire: instrument development and testing. BMC pregnancy and childbirth, 14(1), p.188.

Hutton, E.K., Reitsma, A., Thorpe, J., Brunton, G. and Kaufman, K., 2014. Protocol: systematic review and meta-analyses of birth outcomes for women who intend at the onset of labour to give birth at home compared to women of low obstetrical risk who intend to give birth in hospital. Systematic reviews, 3(1), p.55.

Gitsels–van der Wal, J.T., Manniën, J., Gitsels, L.A., Reinders, H.S., Verhoeven, P.S., Ghaly, M.M., Klomp, T. and Hutton, E.K., 2014. Prenatal screening for congenital anomalies: exploring midwives’ perceptions of counseling clients with religious backgrounds. BMC pregnancy and childbirth, 14(1), p.237.

Martin, L., Hutton, E.K., Spelten, E.R., Gitsels-van der Wal, J.T. and van Dulmen, S., 2014. Midwives’ views on appropriate antenatal counselling for congenital anomaly tests: Do they match clients’ preferences?. Midwifery, 30(6), pp.600-609.

Pereboom, M.T., Manniën, J., Spelten, E.R., Hutton, E.K. and Schellevis, F.G., 2014. Maternal cytomegalovirus infection prevention: The role of Dutch primary care midwives. Midwifery, 30(12), pp.1196-1201.

Hutton, E.K., Hannah, M.E., Ross, S., Asztalos, E.V., Willan, A.R., Allen, A.C., Armson, A.B., Gafni, A., Joseph, K.S., Ohlsson, A. and Barrett, J.F., 2014, March. Maternal 3 Month Outcomes after Planned Cesarean (CS) vs Planned Vaginal Birth (VB) for Twin Pregnancies: The Twin Birth Study (TBS). Reproductive Sciences (Vol. 21, No. 3,  pp. 284A-284A).

Pereboom, M.T., Spelten, E.R., Manniën, J., Rours, G.I.J., Morré, S.A., Schellevis, F.G. and Hutton, E.K., 2014. Knowledge and acceptability of Chlamydia trachomatis screening among pregnant women and their partners; a cross-sectional study. BMC public health, 14(1), p.704.

Manniën, J., de Jonge, A., Cornel, M.C., Spelten, E. and Hutton, E.K., 2014. Factors associated with not using folic acid supplements preconceptionally. Public health nutrition, 17(10), pp.2344-2350.

Gitsels-van der Wal, J.T., Verhoeven, P.S., Manniën, J., Martin, L., Reinders, H.S., Spelten, E. and Hutton, E.K., 2014. Factors affecting the uptake of prenatal screening tests for congenital anomalies; a multicentre prospective cohort study. BMC pregnancy and childbirth, 14(1), p.264.

Murray-Davis, B., McDonald, H., Rietsma, A., Coubrough, M. and Hutton, E., 2014. Deciding on home or hospital birth: Results of the Ontario choice of birthplace survey. Midwifery, 30(7), pp.869-876.

Barrett, J., Asztalos, E., Willan, A., Hannah, M., Hutton, E., Allen, A., Armson, B.A., Gafni, A., Joseph, K., Ohlsson, A. and Ross, S., 2014. Twin Birth Study: an analysis of the predictors for a successful planned vaginal twin birth. American Journal of Obstetrics & Gynecology, 210(1), p.S293.

Wainman, B., Murray-Davis, B., McDonald, H., Hutton, E., Cheng, E. and Geurts, C., 2013. Pharmacology revealed-an enhanced e-book for midwifery education. The FASEB Journal, 27(1 Supplement), pp.665-6.

Barrett, J., Aztalos, E., Willan, A., Joseph, K., Armson, B.A., Hutton, E., Allen, A., Ohlsson, A., Ross, S., Farrell, S. and Gafni, A., 2013. The Twin Birth Study: a multicenter RCT of planned cesarean section (CS) and planned vaginal birth (VB) for twin pregnancies 320 to 386/7 weeks. American Journal of Obstetrics & Gynecology, 208(1), pp.S4-S5.

Kuppens, S.M., Brugman, A., Hasaart, T.H., Hutton, E.K. and Pop, V.J., 2013. The effect of change in a labour management protocol on caesarean section rate in nulliparous women. Journal of Obstetrics and Gynaecology Canada, 35(6), pp.508-514.

Martin, L., Van Dulmen, S., Spelten, E., De Jonge, A., De Cock, P. and Hutton, E., 2013. Prenatal counseling for congenital anomaly tests: parental preferences and perceptions of midwife performance. Prenatal diagnosis, 33(4), pp.341-353.

Pereboom, M.T., Manniën, J., Spelten, E.R., Schellevis, F.G. and Hutton, E.K., 2013. Observational study to assess pregnant women’s knowledge and behaviour to prevent toxoplasmosis, listeriosis and cytomegalovirus. BMC pregnancy and childbirth, 13(1), p.98.

Kuppens, S.M., Hutton, E.K., Hasaart, T.H., Aichi, N., Wijnen, H.A. and Pop, V.J., 2013. Mode of delivery following successful external cephalic version: comparison with spontaneous cephalic presentations at delivery. Journal of Obstetrics and Gynaecology Canada, 35(10), pp.883-888.

Klomp, T., de Jonge, A., Hutton, E.K. and Lagro-Janssen, A.L., 2013. Dutch women in midwife-led care at  the onset of labour: which pain relief do they prefer and what do they use?. BMC Pregnancy and childbirth, 13(1),  p.230.

Baas, C., Wiegers, T., de Cock, P., Koelewijn, J. and Hutton, E., 2013. Continuous support during childbirth by maternity care assistants: An exploration of opinions in the Netherlands. International Journal of Childbirth, 3(2),  pp.76-85.

Hutton, E.K., Stoll, K. and Taha, N., 2013. An observational study of umbilical cord clamping practices of maternity care providers in a tertiary care center. Birth, 40(1), pp.39-45.

De Jonge, A., Baron, R., Westerneng, M., Twisk, J. and Hutton, E.K., 2013. Perinatal mortality rate in the Netherlands compared to other European countries: a secondary analysis of Euro-PERISTAT data. Midwifery, 29(8),  pp.1011-1018.

Baron, R., Manniën, J., de Jonge, A., Heymans, M.W., Klomp, T., Hutton, E.K. and Brug, J., 2013. Socio- demographic and lifestyle-related characteristics associated with self-reported any, daily and occasional smoking during pregnancy. PLoS One, 8(9), p.e74197.

Barrett, J.F., Hannah, M.E., Hutton, E.K., Willan, A.R., Allen, A.C., Armson, B.A., Gafni, A., Joseph, K.S., Mason, D., Ohlsson, A. and Ross, S., 2013. A randomized trial of planned cesarean or vaginal delivery for twin pregnancy. New England Journal of Medicine, 369(14), pp.1295-1305.

Murray-Davis B, Marion A, Malott A, Reitsma A, Hutton E for the Early ECV2 Trial Collaborative Group. Women’s experiences of participating in the ECV2 Trial. Birth;39(1):1-9. doi: 10.111/j.1523-536X.2011.00510.x. Epub  2012 Jan 9

Murray-Davis, B., McNiven, P., McDonald, H., Malott, A., Elarar, L. and Hutton, E., 2012. Why home birth? A qualitative study exploring women’s decision making about place of birth in two Canadian provinces. Midwifery, 28(5), pp.576-581.

Sword, W., Heaman, M.I., Brooks, S., Tough, S., Janssen, P.A., Young, D., Kingston, D., Helewa, M.E., Akhtar-Danesh, N. and Hutton, E., 2012. Women’s and care providers’ perspectives of quality prenatal care: a qualitative descriptive study. BMC pregnancy and childbirth, 12(1), p.29.

Murray-Davis, B., Marion, A., Malott, A., Reitsma, A. and Hutton, E.K., 2012. Women’s experiences of participating in the early external cephalic version 2 trial. Birth, 39(1), pp.30-38.

Srinivasjois RM, Shah S, Shah PS: Knowledge Synthesis Group on Determinants Of Preterm/LBW Births (including Hutton EK). Biracial couples and adverse birth outcomes: a systematic review and meta-analyses. Acta Obstet Gynecol Scand. 2012 Oct;91(10):1134-46. di: 10.1111/j.1600-0412.2012.01501.x. Epub 2012 Aug 24. Review

De Hundt, M., Vlemmix, F., Bais, J.M.J., Hutton, E.K., De Groot, C.J., Mol, B.W.J. and Kok, M., 2012. Risk factors for developmental dysplasia of the hip: a meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 165(1), pp.8-17.

van Rheenen P, Hutton E Less iron deficiency after late cord clamping. Journal for Midwives.Inst. Rijnstate Hospital, Arnhem, NL. 29-32. December 1, 2012.

McDonald, S.D., Pullenayegum, E., Bracken, K., Chen, A.M., McDonald, H., Malott, A., Hutchison, R., Haley, S., Lutsiv, O., Taylor, V.H. and Good, C., 2012. Comparison of midwifery, family medicine, and obstetric patients’ understanding of weight gain during pregnancy: a minority of women report correct counselling. Journal of Obstetrics and Gynaecology Canada, 34(2), pp.129-135.

Hutton, E.K., Hannah, M.E., Ross, S.J., Delisle, M.F., Carson, G.D., Windrim, R., Ohlsson, A., Willan, A.R., Gafni, A., Sylvestre, G. and Natale, R., 2012. The Early External Cephalic Version 2 Trial: An International Multicenter Randomized-controlled Trial of Timing of ECV for Breech Pregnancies. Obstetric Anesthesia Digest, 32(2), p.128.

Martin, L., Dulmen, S.V., Spelten, E. and Hutton, E., 2012. Prenatal genetic counseling: future parents prefer to make decisions together, using professional advice.  NIVEL – The Netherlands Institute for Health Services Research

Hutton, E.K. and Kornelsen, J., 2012. Patient-Initiated Elective Cesarean Section of Nulliparous Women in British Columbia, Canada. Birth, 39(3), pp.175-182.

Malott, A.M., Kaufman, K., Thorpe, J., Saxell, L., Becker, G., Paulette, L., Ashe, A., Martin, K., Yeates, L. and Hutton, E.K., 2012. Models of organization of maternity care by midwives in Canada: a descriptive review. Journal of Obstetrics and Gynaecology Canada, 34(10), pp.961-970.

Manniën, J., Klomp, T., Wiegers, T., Pereboom, M., Brug, J., de Jonge, A., van der Meijde, M., Hutton, E., Schellevis, F. and Spelten, E., 2012. Evaluation of primary care midwifery in the Netherlands: design and rationale of a dynamic cohort study (DELIVER). BMC health services research, 12(1), p.69.

Kornelsen, J. and Hutton, E., 2012. Attributes and Experiences of Patient-Initiated Elective Cesarean Section. Canadian Journal of Midwifery Research and Practice, 11(1), p.9.

Stoll, K. and Hutton, E., 2012. A Survey of Umbilical Cord Clamping Practices and Attitudes of Canadian Maternity Care Providers-Survol des pratiques en matière de clampage du cordon ombilical et des attitudes des fournisseurs de soins obstétricaux canadiens. Canadian Journal of Midwifery Research and Practice, 11(3), p.18.

Hall, W.A., Stoll, K., Hutton, E.K. and Brown, H., 2012. A prospective study of effects of psychological factors and sleep on obstetric interventions, mode of birth, and neonatal outcomes among low-risk British Columbian women. BMC pregnancy and childbirth, 12(1), p.78.

Spelten, E., Gitsels, J., Pereboom, M., Martin, L., Hutton, E. and Dulmen, S.V., 2012. Video recording to improve the quality of prenatal genetic counselling.  NIVEL – The Netherlands Institute for Health Services Research

McDonald, S.D., Pullenayegum, E., Taylor, V., Lutsiv, O., Bracken, K., Good, C., Hutton, E., Chen, A.M., Hutchison, R., Malott, A. and McDonald, H., 2011. 182-Three-quarters of overweight and obese women are planning on exceeding the gestational weight gain recommendations. Canadian Journal of Diabetes, 35(2), p.187.

McDonald SD, Han Z, Mulla S, Lutisv O, Lee T, Beyene J; Knowledge Synthesis Group. High gestational weight gain and the risk of preterm birth and low birth weight; a systematic review and meta-analysis. J Obstet Gynaecol Can. 2011 Dec;33(12):1223-33

Malott, A.M., Davis, B.M., McDonald, H. and Hutton, E., 2009. Midwifery care in eight industrialized countries: how does Canadian midwifery compare?. Journal of Obstetrics and Gynaecology Canada, 31(10), pp.974-979.

BIO

Dr. Waldo Jimenez completed his degree in medicine at Universidad de Concepcion, Chile in 1997. He completed residency training in obstetrics and gynecology at Universidad Catolica, Chile in 2000. He then went on to complete a masters in clinical epidemiology at the University of Toronto in 2007, while also completing his fellowship in obstetrics and gynecology at the University of Toronto in 2008.

Dr. Jimenez was an assistant professor in the Department of Obstetrics & Gynecology, Universidad Catolica, Concpecion, Chile from 2000–05. He then became an assistant professor in the Department of Obstetrics & Gynecology at the University of Toronto, Credit Valley Hospital from 2008–10. Dr. Jimenez became an assistant professor in the Department of Obstetrics & Gynecology at McMaster University, Juravinski Cancer Centre in 2010, and since 2016 has held the rank of associate professor.

AWARDS

2012 – McMaster University, Council on Resident Education in Obstetrics and Gynecology (CREOG) National Faculty Award for Excellence in Resident Education

RESEARCH INTERESTS

Ongoing Research

Prospective cohort study evaluating identification rate of sentinel node in the management of endometrial cancer utilizing a combined method of cervical and myometrial injections.

Role: principal investigator

Grant: Juravinski Cancer Centre Foundation

PUBLICATIONS

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS-0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Covens, A., Vella, E.T., Kennedy, E.B., Reade, C.J., Jimenez, W. and Le, T., 2015. Sentinel lymph node biopsy in vulvar cancer: systematic review, meta-analysis and guideline recommendations. Gynecologic oncology, 137(2), pp.351-361

Rosen, B., Dodge, J., Giede, C., Jimenez, W., Cibulska, P., Sinesat, S., Bernardini, M., Mcalpine, J., Finlayson, S., Miller, D. and Elkanah, O., 2012. Implementation of oncology surgery in Western Kenya. Canadian Medical Association Journal, 55(4), p.284.

Reade, C.J., Jimenez, W., O’Reilly, D. and Covens, A., 2012. Sentinel lymph node biopsy in vulvar cancer: a health technology assessment for the canadian health care context. Journal of Obstetrics and Gynaecology Canada, 34(11), pp.1053-1065.

Elit, L., Jimenez, W., McAlpine, J., Ghatage, P., Miller, D. and Plante, M., 2011. Prévention du cancer du col utérin au sein de milieux ne disposant que de faibles ressources. Journal of Obstetrics and Gynaecology Canada, 33(3), pp.280-288.

Elit, L., LaRoche, A., Smith, L., Mazurka, J., Moens, F., Hauspy, J. and Jimenez, W., 2011. Management of women with surgically staged 1 uterine papillary serous cancer. ISRN obstetrics and gynecology, 2011.

Elit, L., Jimenez, W., McAlpine, J., Ghatage, P., Miller, D. and Plante, M., 2011. Cervical cancer prevention in low-resource settings. Journal of Obstetrics and Gynaecology Canada, 33(3), pp.272-279.

Hauspy, Jan, Waldo Jiménez, Barry Rosen, Walter H. Gotlieb, Michael Fung-Kee-Fung, and Marie Plante. “Laparoscopic surgery for endometrial cancer: a review.” Journal of Obstetrics and Gynaecology Canada 32, no. 6 (2010): 570-579.

Gortzak-Uzan, L., Jimenez, W., Nofech-Mozes, S., Ismiil, N., Khalifa, M.A., Dubé, V., Rosen, B., Murphy, J., Laframboise, S. and Covens, A., 2010. Sentinel lymph node biopsy vs. pelvic lymphadenectomy in early stage cervical cancer: is it time to change the gold standard?. Gynecologic oncology, 116(1), pp.28-32.

Elit, L.M., Rosen, B., Jimenez, W., Giede, C., Cybulska, P., Sinasac, S., Dodge, J., Ayush, E., Omenge, O., Bernardini, M. and Finlayson, S., 2010. Teaching cervical cancer surgery in low-or middle-resource countries. International Journal of Gynecological Cancer, 20(9), pp.1604-1608.

Jiménez, W., Paszat, L., Kupets, R., Wilton, A. and Tinmouth, J., 2009. Presumed previous human papillomavirus (HPV) related gynecological cancer in women diagnosed with anal cancer in the province of Ontario. Gynecologic oncology, 114(3), pp.395-398.

BIO

Dr. Waldo Jimenez completed his degree in medicine at Universidad de Concepcion, Chile in 1997. He completed residency training in obstetrics and gynecology at Universidad Catolica, Chile in 2000. He then went on to complete a masters in clinical epidemiology at the University of Toronto in 2007, while also completing his fellowship in obstetrics and gynecology at the University of Toronto in 2008.

Dr. Jimenez was an assistant professor in the Department of Obstetrics & Gynecology, Universidad Catolica, Concpecion, Chile from 2000–05. He then became an assistant professor in the Department of Obstetrics & Gynecology at the University of Toronto, Credit Valley Hospital from 2008–10. Dr. Jimenez became an assistant professor in the Department of Obstetrics & Gynecology at McMaster University, Juravinski Cancer Centre in 2010, and since 2016 has held the rank of associate professor.

AWARDS

2012 – McMaster University, Council on Resident Education in Obstetrics and Gynecology (CREOG) National Faculty Award for Excellence in Resident Education

RESEARCH INTERESTS

Ongoing Research

Prospective cohort study evaluating identification rate of sentinel node in the management of endometrial cancer utilizing a combined method of cervical and myometrial injections.

Role: principal investigator

Grant: Juravinski Cancer Centre Foundation

PUBLICATIONS

Jimenez, W., Maxwell, J., Daya, D., Sur, M., Elit, L., Eiriksson, L., Reade, C. and Lytwyn, A., 2015. UNDIFFERENTIATED ENDOMETRIAL CANCER, A DIFFERENT ENTITY WITH AN AGGRESSIVE BEHAVIOR: IGCS-0060 Uterine Cancer, including Sarcoma. International Journal of Gynecological Cancer, 25, p.69.

Covens, A., Vella, E.T., Kennedy, E.B., Reade, C.J., Jimenez, W. and Le, T., 2015. Sentinel lymph node biopsy in vulvar cancer: systematic review, meta-analysis and guideline recommendations. Gynecologic oncology, 137(2), pp.351-361

Rosen, B., Dodge, J., Giede, C., Jimenez, W., Cibulska, P., Sinesat, S., Bernardini, M., Mcalpine, J., Finlayson, S., Miller, D. and Elkanah, O., 2012. Implementation of oncology surgery in Western Kenya. Canadian Medical Association Journal, 55(4), p.284.

Reade, C.J., Jimenez, W., O’Reilly, D. and Covens, A., 2012. Sentinel lymph node biopsy in vulvar cancer: a health technology assessment for the canadian health care context. Journal of Obstetrics and Gynaecology Canada, 34(11), pp.1053-1065.

Elit, L., Jimenez, W., McAlpine, J., Ghatage, P., Miller, D. and Plante, M., 2011. Prévention du cancer du col utérin au sein de milieux ne disposant que de faibles ressources. Journal of Obstetrics and Gynaecology Canada, 33(3), pp.280-288.

Elit, L., LaRoche, A., Smith, L., Mazurka, J., Moens, F., Hauspy, J. and Jimenez, W., 2011. Management of women with surgically staged 1 uterine papillary serous cancer. ISRN obstetrics and gynecology, 2011.

Elit, L., Jimenez, W., McAlpine, J., Ghatage, P., Miller, D. and Plante, M., 2011. Cervical cancer prevention in low-resource settings. Journal of Obstetrics and Gynaecology Canada, 33(3), pp.272-279.

Hauspy, Jan, Waldo Jiménez, Barry Rosen, Walter H. Gotlieb, Michael Fung-Kee-Fung, and Marie Plante. “Laparoscopic surgery for endometrial cancer: a review.” Journal of Obstetrics and Gynaecology Canada 32, no. 6 (2010): 570-579.

Gortzak-Uzan, L., Jimenez, W., Nofech-Mozes, S., Ismiil, N., Khalifa, M.A., Dubé, V., Rosen, B., Murphy, J., Laframboise, S. and Covens, A., 2010. Sentinel lymph node biopsy vs. pelvic lymphadenectomy in early stage cervical cancer: is it time to change the gold standard?. Gynecologic oncology, 116(1), pp.28-32.

Elit, L.M., Rosen, B., Jimenez, W., Giede, C., Cybulska, P., Sinasac, S., Dodge, J., Ayush, E., Omenge, O., Bernardini, M. and Finlayson, S., 2010. Teaching cervical cancer surgery in low-or middle-resource countries. International Journal of Gynecological Cancer, 20(9), pp.1604-1608.

Jiménez, W., Paszat, L., Kupets, R., Wilton, A. and Tinmouth, J., 2009. Presumed previous human papillomavirus (HPV) related gynecological cancer in women diagnosed with anal cancer in the province of Ontario. Gynecologic oncology, 114(3), pp.395-398.

BIO

Dr. Karnis is originally from Toronto. She pursued her undergraduate studies at McMaster University, where she earned a bachelor of arts and science. In 1993, she graduated from medical school at McMaster University. Dr. Karnis completed her internship at the University of Toronto, in the Department of Obstetrics and Gynecology. She then returned to McMaster for her residency in obstetrics and oynecology. Upon completion of her residency, Dr. Karnis moved to Boston, Massachusetts where she engaged in a three-year fellowship in reproductive endocrinology and infertility at Harvard Medical School, in conjunction with the Beth Israel Deaconess Medical Center and Boston IVF. Following her subspeciality training, she returned to Hamilton and joined the Hamilton Health Sciences Centre for Reproductive Care. In 2009, the Centre for Reproductive Care closed and she opened The Ontario Network of Experts in Fertility (ONE Fertility) with partners Dr. Shilpa Amin (GREI) and Mr. Mike Neal (Embryology). ONE Fertility is a full service fertility centre and reproductive endocrinology clinic. Dr. Karnis is a fellow of the Royal College of Physicians and Surgeons of Canada and is U.S. Board Eligible in obstetrics and gynecology and reproductive endocrinology and infertility.

RESEARCH INTERESTS

Research Themes

Infertility; Reproductive endocrinology; Turner syndrome

PUBLICATIONS

Tan, L., Krichevsky, L., Greenblatt, E., Casper, R., Laskin, C.A., Sierra, S., Hannam, T., Karnis, M.F., Librach, C.L. and Sharma, P.A., 2016. Retrospective analysis of the efficacy of ART and reproductive outcomes in females with Fragile X associated primary ovarian insufficiency. Fertility and Sterility, 106(3), p.e241.

Lin, A.E., Karnis, M.F., Calderwood, L., Crenshaw, M., Bhatt, A., Souter, I., Silberbach, M. and Reindollar, R.H., 2016. Proposal for a national registry to monitor women with Turner syndrome seeking assisted reproductive technology. Fertility and sterility, 105(6), pp.1446-1448.

Taerk, E., Hughes, E., Greenberg, C., Neal, M., Amin, S., Faghih, M. and Karnis, M., 2016. Choriogonadotropin alpha administration is associated with an increased clinical pregnancy rate among infertile couples undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertility and Sterility, 105(2), pp.e39-e40.

Deniz, S.G., Hughes, E.G., Neal, M.S., Faghih, M., Amin, S. and Karnis, M.F., 2016. Are health care providers adequately educating couples for embryo disposition decisions?. Fertility and sterility, 105(3), pp.684-689.

Faghih, M., Deniz, S., Neal, M., Amin, S., Hughes, E. and Karnis, M., 2013. Impact of active cycle endometrial biopsy on implantation and pregnancy rates in fresh IVF cycles in patients with history of implantation failure. Fertility and Sterility, 100(3), p.S293.

Karnis, M., 2012. Fertility, pregnancy, and medical management of Turner syndrome in the reproductive years. Fertility and Sterility, 98(4), 787-791.

Karnis, M., 2012. Catastrophic Consequences of Assisted Reproduction: The Case of Turner Syndrome. Seminars in Reproductive Medicine, 30(02), 116-122.

Willoughby, K., DiPaolo, L., Deys, L., Lagunov, A., Amin, S., Faghih, M., Hughes, E., Karnis, M., Ashkar, F., King, W.A. and Neal, M.S., 2011. P-152 Comparison of serum and follicular fluid thyrotropin levels and human embryo development in vitro. Human Reproduction, 26(suppl_1), pp.i182-i183.

Neal, M.S., DiPaolo, L., Willoughby, K., Faghih, M., Karnis, M., Hughes, E.G. and Portwine, C., 2008. Fertility preservation for young women with cancer: Hope for the future. Current Women’s Health Reviews, 4(4), pp.258-265.