Information Box Group
Nicholas Leyland
BASc, MD, MHCM, FRCSC
Professor
General, Minimally Invasive Gynaecological Surgery
BIO
Dr. Nicholas Leyland earned his bachelor of applied science from the University of Guelph in 1979, and his medical degree from the University of Toronto in 1983. In 1988, he earned his FRCSC. In 2006, he graduated Summa Cum Lauda from Harvard University with a master’s of health care management. Dr. Leyland joined the Faculty of Health Sciences at McMaster University as an associate clinical professor in obstetrics and gynecology in 2009. On July 1, 2010, Dr. Leyland became professor and chair of the Department of Obstetrics & Gynecology.
RESEARCH
Research Themes
Endometriosis; Pelvic pain; Biomarkers; Abnormal uterine bleeding; Clinical practice guidelines; Minimally invasive surgery; Uterine fibroids; Selective progesterone receptor modulators; Perioperative surgical pain optimization; Simulation in surgical training
PUBLICATIONS
Taylor, H. S., Giudice, L. C., Lessey, B. A., Abrao, M. S., Kotarski, J., Archer, D. F.,… & Gallagher, J. C. (2017). Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. The New England journal of medicine. 377(1), p.28-40.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Mosher, A., Tsoulis, M., Leyland, N. and Foster, W., 2017.The Role of Melatonin and Prostaglandins in Endometriosis. Journal of Obstetrics and Gynaecology Canada, 39(5), p.398.
Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. (2017). Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. Journal of Obstetrics and Gynaecology Canada.
Arendas, K., Singh, S.S., Jackie, T., Clancy, A. and Leyland, N., 2017. Laparoscopic Cerclage: Challenging Cases. Journal of Obstetrics and Gynaecology Canada, 39(5), p.382.
Laberge, P., Garza-Leal, J., Fortin, C., Grainger, D., Johns, D.A., Adkins, R.T., Presthus, J., Basinski, C., Swarup, M., Gimpelson, R. and Leyland, N., 2017. A Randomized Controlled Multicenter US Food and Drug Administration Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System: One-Year Follow-Up Results. Journal of minimally invasive gynecology, 24(1), pp.124-132.
Leung, S., Leyland, N. and Murji, A., 2016. Decreasing Diagnostic Hysteroscopy Performed in the Operating Room: A Quality Improvement Initiative. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.351-356.
Arendas, K. and Leyland, N.A., 2016. Use of ulipristal acetate for the management of fibroid-related acute abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 38(1), pp.80-83.
Murji, A., De Gasperis-Brigante, C. and Leyland, N., 2016. Richter’s Hernia After Laparoscopic Surgery. Journal of Minimally Invasive Gynecology, 24(4), pp.518-19.
Vilos, G.A., Allaire, C., Laberge, P.Y. and Leyland, N., 2016. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S550-S576.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N., Solnik, J. and Murji, A., 2016. Does Ulipristal Acetate Objectively Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology, 23(7), pp.S2-S3.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.
Laberge, P.Y., Garza-Leal, J., Fortin, C., Thiel, J., Johns, D.A., Grainger, D., Presthus, J., Adkins, T., Leyland, N., Basinski, C. and Gimpelson, R., 2016. A Randomized, Controlled, Multi-Center Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System. One-Year Follow-Up Results. Journal of Minimally Invasive Gynecology, 23(7), p.S44.
Wessels, J.M., Kay, V.R., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2016. Assessing brain-derived neurotrophic factor as a novel clinical marker of endometriosis. Fertility and Sterility, 105(1), pp.119-128.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P. and Vilos, G., 2016. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S609-S628.
Singh, S., Best, C., Dunn, S., Leyland, N. and Wolfman, W.L., 2016. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S231-S263.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.179-181.
Leyland, N., 2015. Myomectomy After Uliprisal Acetate. Journal of Minimally Invasive Gynecology, 22(6), p.S144.
Singh, S.S., Scott, S., Bougie, O. and Leyland, N., 2016. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S537-S549.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.79-81.
Arendas, K., Aldossary, M., Cipolla, A., Leader, A. and Leyland, N.A., 2015. Hysteroscopic resection in the management of early-stage endometrial cancer: report of 2 cases and review of the literature. Journal of minimally invasive gynecology, 22(1), pp.34-39.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Endometrial ablation in the management of abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.362-376.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.377-379.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Ahmed, R., Simioni, J., Dore, S., Marrin, M., DeSantis, J., Leyland, N., Gardosi, J. and Hutton, E., 2015. Learning from Adverse Events in Obstetrics: Is a Standardized Computer Tool an Effective Strategy for Root Cause Analysis?. Journal of Obstetrics and Gynaecology Canada, 37(8), pp.728-735.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2015. Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors. Human Reproduction, p.dev018.
Arendas, K., Foster, W.G. and Leyland, N.A., 2015. Impact of surgical excision of deep infltratng bowel endometriosis on health-related quality of life: review of current literature. Journal of Endometriosis and Pelvic Pain Disorders, 7(1), pp.3-9.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.68-78.
Arendas, K., Coll-Black, M. and Leyland, N.A., 2015. Approach to the Obliterated Posterior Cul-De-Sac. Journal of Minimally Invasive Gynecology, 22(6), p.S120.
Leyland, N.A., 2015. The Selective Progesterone Receptor Modulator, Ulipristal Acetate, in the Management of Symptomatic Uterine Fibroids. Journal of minimally invasive gynecology, 22(6S), p.S73.
Bougie, O., Murji, A., Arendas, K., Vilos, G., Allaire, C., Laberge, P., Leyland, N., Chen, I. and Singh, S.S., 2015. Power Morcellation in Gynecologic Surgery: A Survey of Canadian Practice. Journal of Minimally Invasive Gynecology, 22(6), p.S99.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. The management of uterine leiomyomas. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.157-178.
Arendas, K. and Leyland, N.A., 2014. Para-Ovarian Endomerioma in a Patient with a Congenital Uterine Anomaly. Journal of Minimally Invasive Gynecology, 21(6), p.S216.
Wessels, J.M., Wu, L., Leyland, N.A., Wang, H. and Foster, W.G., 2014. The brain-uterus connection: brain derived neurotrophic factor (BDNF) and its receptor (Ntrk2) are conserved in the mammalian uterus. PloS one, 9(4), p.e94036.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2014. Good proteins gone bad: brain-derived neurotrophic factor and its receptors in endometriotic implants and the role of estrogen. Fertility and Sterility, 102(3), pp.e10-e11.
Arendas, K., Al-Dossary, M.I., Leader, A. and Leyland, N.A., 2014. Successful Pregnancy after Targeted Hysteroscopy for Endometrial Adenocarcinoma. Journal of Minimally Invasive Gynecology, 21(6), p.S7.
Thiel, J.A., Rattray, D.D. and Leyland, N., 2014. Laparoscopic Radiofrequency Volumetric Thermal Ablation (RFVTA) of Symptomatic Fibroids and Myomectomy: A Randomized Trial of Uterine-Sparing Techniques in Canada. Journal of Minimally Invasive Gynecology, 21(6), p.S101.
Clancy, A. A., N. Leyland, and S. S. Singh. “Approach to Laparoscopic Cerclage.” Journal of Minimally Invasive Gynecology 21, no. 6 (2014): S65.
Tepperman, E.D., Sobel, M.L., Murji, A. and Leyland, N.A., 2014. Appendectomy in Gynecology. Journal of Minimally Invasive Gynecology, 21(6), p.S20.
Toor, K., Wessels, J.M., Agarwal, S.K., Leyland, N. and Foster, W.G., 2014. Clinical markers of endometriosis: have we been too quick to judge?. Medical hypotheses, 82(4), pp.493-501.
Laberge, P., Garza-Leal, J., Fortin, C., Basinski, C., Thiel, J., Leyland, N., Presthus, J., Johns, A., Grainger, D., Adkins, T. and Swarup, M., 2014. A Prospective, Randomized, Multi-Center, Controlled, International Clinical Study of the Safety and Efficacy of the MINERVA Endometrial Ablation System. 6 & 12-Months Follow-Up Results. Journal of Minimally Invasive Gynecology, 21(6), p.S144.
Arendas, K. and Leyland, N.A., 2014. Ulipristal Acetate for the Management of Acute Fibroid-Related Menorrhagia. Journal of Minimally Invasive Gynecology, 21(6), p.S196.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., CLINIQUE-GYNECOLOGIE, C.D.P., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M. and Lemyre, M., 2013. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.476-479.
Wessels, J.M., Leyland, N.A., Agarwal, S., Murji, A. and Foster, W.G., 2013. Can brain-derived neurotrophic factor be a clinical marker for endometriosis?. Fertility and Sterility, 100(3), pp.S101-S102.
Murji, A., Sobel, M. and Leyland, N., 2013. Uterine and Internal Iliac Artery Ligation: Anatomy and Clinical Applications for Benign Gynecology. The Journal of Minimally Invasive Gynecology, 6(20), p.S182.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., CLINIQUE-GYNÉCOLOGIE, C.D.P., Leyland, N., Wolfman, W. and Allaire, C., 2013. Chirurgie esthétique génitale chez la femme. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1113-1114.
Singh, S.S., Mehra, N., Hopkins, L., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Liste de contrôle de la sécurité chirurgicale en obstétrique-gynécologie. Journal of Obstetrics and Gynaecology Canada, 35(1), pp.84-85.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., Leyland, N., Wolfman, W., Allaire, C. and Awadalla, A., 2013. Female genital cosmetic surgery. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1108-1112.
Murji, A., Glass, K. and Leyland, N., 2013. Isthmocele. Journal of Obstetrics and Gynaecology Canada, 35(9), p.780.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Abnormal uterine bleeding in pre-menopausal women. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.47
Wessels, J.M., Leyland, N. and Foster, W.G., 2012. Uterine Expression of Brain-Derived Neurotrophic Factor (BDNF) and Its Receptor During the Estrous Cycle and Menstrual Cycle. Biology of Reproduction, 87(Suppl 1), pp.335-335.
Lokuge, S., Fruci, V., Abraham, T., Youash, S., Bates, S. and Leyland, N., 2012. Does Innate Motor Skill Predict Medical Student’s Interest in Pursuing a Surgical Specialty?. Journal of Minimally Invasive Gynecology, 19(6), p.S25.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2011. Oral contraceptives and the risk of venous thromboembolism: an update. International Journal of Gynecology & Obstetrics, 112(3), pp.252-256.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Asymptomatic endometrial thickening. Journal of Obstetrics and Gynaecology Canada, 32(10), pp.990-999.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Adhesion prevention in gynaecological surgery. International Journal of Gynecology & Obstetrics, 111(2), pp193-7.
Leyland, N., Casper, R., Laberge, P., Singh, S.S., Allen, L., Arendas, K., Allaire, C., Awadalla, A., Best, C., Contestabile, E. and Dunn, S., 2010. Endometriosis: diagnosis and management. Journal of Obstetrics and Gynaecology Canada, 32(7), pp.S1-S3.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Épaississement endométrial asymptomatique. Journal of Obstetrics and Gynaecology Canada, 32(11), pp.1070-1081.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Hystérectomie supracervicale. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.69-76.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Prévention des adhérences en chirurgie gynécologique. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.603-608.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Supracervical hysterectomy. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.62-68.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2010. Oral contraceptives and the risk of venous thromboembolism: an update. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1192-1197.
Nicholas Leyland
BASc, MD, MHCM, FRCSC
Professor
General, Minimally Invasive Gynaecological Surgery
Mathew Leonardi
Assistant Professor
Minimally Invasive Gynaecological Surgery
Mathew Leonardi
Assistant Professor
Minimally Invasive Gynaecological Surgery
Lea Luketic
MSc, MD, FRCSC
Assistant Professor
General
BIO
Dr. Lea Luketic is currently an assistant professor of obstetrics and gynecology at McMaster University and a practicing obstetrician and gynecologist at St. Joseph’s Healthcare. She earned her bachelor of science at the University of Guelph and a master of science at McMaster University. She obtained her MD from the University of Toronto in 2010. Her residency training in obstetrics and gynecology was completed at McMaster University in 2015. She then went on to complete a fellowship in minimally invasive gynecologic surgery at Mount Sinai Hospital at the University of Toronto and joined the Department of Obstetrics & Gynecology at McMaster University in 2017. She is currently working on finishing a master of science in healthcare quality at Queen’s University.
Awards
Resident Teaching Award in 2015
RESEARCH INTERESTS
Research Themes
Uterine fibroids; Patient safety; Healthcare quality; Minimally invasive gynecologic surgery
PUBLICATIONS
Luketic, L., Jacobson, M., Allen, L., Bernardini, M. and Sobel, M., 2017. Risk-Reducing Salpingo-Oophorectomy in BRCA Mutation Carriers. Journal of Obstetrics and Gynaecology Canada, 39(5), p.397.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Zwayne, N., Kives, S., Luketic, L. and Allen, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Pediatric and Adolescent Gynecology, 29(2), p.165
Zwayne, N., Allen, L., Kives, S. and Luketic, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Obstetrics and Gynaecology Canada, 38(5), p.504.
Luketic, L., Sobel, M. and Murji, A., 2016. Surgical Management of Cesarean Scar Pregnancy. Journal of Minimally Invasive Gynecology, 23(7), p.S154.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World Without Indigo Carmine. Journal of Obstetrics and Gynaecology Canada, 38(5), p.493.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World without Indigo Carmine. Journal of Minimally Invasive Gynecology, 23(7), p.S157.
Luketic, L. and Murji, A., 2016. Options to Evaluate Ureter Patency at Cystoscopy in a World Without Indigo Carmine. Journal of minimally invasive gynecology, 23(6), pp.878-885.
White-Campbell, M., Luketic, L. and MacDonald, S., 2014. Psychosocial groupwork for older adults having substance use and mental health issues. Groupwork, 24(1), pp.60-80.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Luketic, L., Delanghe, J., Sobol, P.T., Yang, P., Frotten, E., Mossman, K.L., Gauldie, J., Bramson, J. and Wan, Y., 2007. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. The Journal of Immunology, 179(8), pp.5024-5032.
Lea Luketic
MSc, MD, FRCSC
Assistant Professor
General
Meghan O'Leary
Assistant Professor
Minimally Invasive Gynaecological Surgery
BIO
Dr. Meghan O’Leary (she/her) is a Minimally Invasive Gynecologic Surgeon working at St. Joseph’s Healthcare in Hamilton, Ontario affiliated with McMaster University. She completed her residency in OBGYN at McMaster University and followed this with a 2-year MIGS fellowship in Calgary, Alberta. The focus of her fellowship training was endometriosis/adenomyosis management with a focus on excisional surgery, in addition to management of fibroids, and other advanced hysteroscopic and laparoscopic operations. Her clinical passions and research interests include medical and surgical education and triaging systems for increasing access to endometriosis specialists. She is an East Coaster at heart, enjoying trips to her hometown of St. John’s, Newfoundland
Meghan O'Leary
Assistant Professor
Minimally Invasive Gynaecological Surgery
Sarah Scattolon
MD, FRCSC
Assistant Professor
General; Minimally Invasive Gynecological Surgery
BIO
Dr. Sarah Scattolon is an academic obstetrician and minimally invasive gynecologic surgeon in the Department of Obstetrics & Gynecology at McMaster University. Dr. Scattolon completed her doctorate of medicine at the University of Toronto and her obstetrics and gynecology residency at McMaster University. She has also completed a two-year fellowship in minimally invasive gynecology surgery at McMaster University.
Dr. Scattolon’s practice focuses on complex gynecologic surgery, endometriosis care, fibroids and low-risk obstetrics. She plays an active role in teaching trainees of all levels and is currently pursuing a master’s in health research methodology with a focus on health services. Dr. Scattolon’s research interests include optimization of medical and surgical treatments of endometriosis, knowledge translation and adherence to clinical practice guidelines.
RESEARCH INTERESTS
Endometriosis; Pelvic pain; Knowledge translation; Clinical practice guidelines; Medical therapies for Endometriosis
Sarah Scattolon
MD, FRCSC
Assistant Professor
General; Minimally Invasive Gynecological Surgery
Nicholas Leyland
BASc, MD, MHCM, FRCSC
Professor
General, Minimally Invasive Gynaecological Surgery
BIO
Dr. Nicholas Leyland earned his bachelor of applied science from the University of Guelph in 1979, and his medical degree from the University of Toronto in 1983. In 1988, he earned his FRCSC. In 2006, he graduated Summa Cum Lauda from Harvard University with a master’s of health care management. Dr. Leyland joined the Faculty of Health Sciences at McMaster University as an associate clinical professor in obstetrics and gynecology in 2009. On July 1, 2010, Dr. Leyland became professor and chair of the Department of Obstetrics & Gynecology.
RESEARCH
Research Themes
Endometriosis; Pelvic pain; Biomarkers; Abnormal uterine bleeding; Clinical practice guidelines; Minimally invasive surgery; Uterine fibroids; Selective progesterone receptor modulators; Perioperative surgical pain optimization; Simulation in surgical training
PUBLICATIONS
Taylor, H. S., Giudice, L. C., Lessey, B. A., Abrao, M. S., Kotarski, J., Archer, D. F.,… & Gallagher, J. C. (2017). Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. The New England journal of medicine. 377(1), p.28-40.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Mosher, A., Tsoulis, M., Leyland, N. and Foster, W., 2017.The Role of Melatonin and Prostaglandins in Endometriosis. Journal of Obstetrics and Gynaecology Canada, 39(5), p.398.
Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. (2017). Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. Journal of Obstetrics and Gynaecology Canada.
Arendas, K., Singh, S.S., Jackie, T., Clancy, A. and Leyland, N., 2017. Laparoscopic Cerclage: Challenging Cases. Journal of Obstetrics and Gynaecology Canada, 39(5), p.382.
Laberge, P., Garza-Leal, J., Fortin, C., Grainger, D., Johns, D.A., Adkins, R.T., Presthus, J., Basinski, C., Swarup, M., Gimpelson, R. and Leyland, N., 2017. A Randomized Controlled Multicenter US Food and Drug Administration Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System: One-Year Follow-Up Results. Journal of minimally invasive gynecology, 24(1), pp.124-132.
Leung, S., Leyland, N. and Murji, A., 2016. Decreasing Diagnostic Hysteroscopy Performed in the Operating Room: A Quality Improvement Initiative. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.351-356.
Arendas, K. and Leyland, N.A., 2016. Use of ulipristal acetate for the management of fibroid-related acute abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 38(1), pp.80-83.
Murji, A., De Gasperis-Brigante, C. and Leyland, N., 2016. Richter’s Hernia After Laparoscopic Surgery. Journal of Minimally Invasive Gynecology, 24(4), pp.518-19.
Vilos, G.A., Allaire, C., Laberge, P.Y. and Leyland, N., 2016. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S550-S576.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N., Solnik, J. and Murji, A., 2016. Does Ulipristal Acetate Objectively Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology, 23(7), pp.S2-S3.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.
Laberge, P.Y., Garza-Leal, J., Fortin, C., Thiel, J., Johns, D.A., Grainger, D., Presthus, J., Adkins, T., Leyland, N., Basinski, C. and Gimpelson, R., 2016. A Randomized, Controlled, Multi-Center Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System. One-Year Follow-Up Results. Journal of Minimally Invasive Gynecology, 23(7), p.S44.
Wessels, J.M., Kay, V.R., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2016. Assessing brain-derived neurotrophic factor as a novel clinical marker of endometriosis. Fertility and Sterility, 105(1), pp.119-128.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P. and Vilos, G., 2016. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S609-S628.
Singh, S., Best, C., Dunn, S., Leyland, N. and Wolfman, W.L., 2016. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S231-S263.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.179-181.
Leyland, N., 2015. Myomectomy After Uliprisal Acetate. Journal of Minimally Invasive Gynecology, 22(6), p.S144.
Singh, S.S., Scott, S., Bougie, O. and Leyland, N., 2016. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S537-S549.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.79-81.
Arendas, K., Aldossary, M., Cipolla, A., Leader, A. and Leyland, N.A., 2015. Hysteroscopic resection in the management of early-stage endometrial cancer: report of 2 cases and review of the literature. Journal of minimally invasive gynecology, 22(1), pp.34-39.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Endometrial ablation in the management of abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.362-376.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.377-379.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Ahmed, R., Simioni, J., Dore, S., Marrin, M., DeSantis, J., Leyland, N., Gardosi, J. and Hutton, E., 2015. Learning from Adverse Events in Obstetrics: Is a Standardized Computer Tool an Effective Strategy for Root Cause Analysis?. Journal of Obstetrics and Gynaecology Canada, 37(8), pp.728-735.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2015. Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors. Human Reproduction, p.dev018.
Arendas, K., Foster, W.G. and Leyland, N.A., 2015. Impact of surgical excision of deep infltratng bowel endometriosis on health-related quality of life: review of current literature. Journal of Endometriosis and Pelvic Pain Disorders, 7(1), pp.3-9.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.68-78.
Arendas, K., Coll-Black, M. and Leyland, N.A., 2015. Approach to the Obliterated Posterior Cul-De-Sac. Journal of Minimally Invasive Gynecology, 22(6), p.S120.
Leyland, N.A., 2015. The Selective Progesterone Receptor Modulator, Ulipristal Acetate, in the Management of Symptomatic Uterine Fibroids. Journal of minimally invasive gynecology, 22(6S), p.S73.
Bougie, O., Murji, A., Arendas, K., Vilos, G., Allaire, C., Laberge, P., Leyland, N., Chen, I. and Singh, S.S., 2015. Power Morcellation in Gynecologic Surgery: A Survey of Canadian Practice. Journal of Minimally Invasive Gynecology, 22(6), p.S99.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. The management of uterine leiomyomas. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.157-178.
Arendas, K. and Leyland, N.A., 2014. Para-Ovarian Endomerioma in a Patient with a Congenital Uterine Anomaly. Journal of Minimally Invasive Gynecology, 21(6), p.S216.
Wessels, J.M., Wu, L., Leyland, N.A., Wang, H. and Foster, W.G., 2014. The brain-uterus connection: brain derived neurotrophic factor (BDNF) and its receptor (Ntrk2) are conserved in the mammalian uterus. PloS one, 9(4), p.e94036.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2014. Good proteins gone bad: brain-derived neurotrophic factor and its receptors in endometriotic implants and the role of estrogen. Fertility and Sterility, 102(3), pp.e10-e11.
Arendas, K., Al-Dossary, M.I., Leader, A. and Leyland, N.A., 2014. Successful Pregnancy after Targeted Hysteroscopy for Endometrial Adenocarcinoma. Journal of Minimally Invasive Gynecology, 21(6), p.S7.
Thiel, J.A., Rattray, D.D. and Leyland, N., 2014. Laparoscopic Radiofrequency Volumetric Thermal Ablation (RFVTA) of Symptomatic Fibroids and Myomectomy: A Randomized Trial of Uterine-Sparing Techniques in Canada. Journal of Minimally Invasive Gynecology, 21(6), p.S101.
Clancy, A. A., N. Leyland, and S. S. Singh. “Approach to Laparoscopic Cerclage.” Journal of Minimally Invasive Gynecology 21, no. 6 (2014): S65.
Tepperman, E.D., Sobel, M.L., Murji, A. and Leyland, N.A., 2014. Appendectomy in Gynecology. Journal of Minimally Invasive Gynecology, 21(6), p.S20.
Toor, K., Wessels, J.M., Agarwal, S.K., Leyland, N. and Foster, W.G., 2014. Clinical markers of endometriosis: have we been too quick to judge?. Medical hypotheses, 82(4), pp.493-501.
Laberge, P., Garza-Leal, J., Fortin, C., Basinski, C., Thiel, J., Leyland, N., Presthus, J., Johns, A., Grainger, D., Adkins, T. and Swarup, M., 2014. A Prospective, Randomized, Multi-Center, Controlled, International Clinical Study of the Safety and Efficacy of the MINERVA Endometrial Ablation System. 6 & 12-Months Follow-Up Results. Journal of Minimally Invasive Gynecology, 21(6), p.S144.
Arendas, K. and Leyland, N.A., 2014. Ulipristal Acetate for the Management of Acute Fibroid-Related Menorrhagia. Journal of Minimally Invasive Gynecology, 21(6), p.S196.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., CLINIQUE-GYNECOLOGIE, C.D.P., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M. and Lemyre, M., 2013. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.476-479.
Wessels, J.M., Leyland, N.A., Agarwal, S., Murji, A. and Foster, W.G., 2013. Can brain-derived neurotrophic factor be a clinical marker for endometriosis?. Fertility and Sterility, 100(3), pp.S101-S102.
Murji, A., Sobel, M. and Leyland, N., 2013. Uterine and Internal Iliac Artery Ligation: Anatomy and Clinical Applications for Benign Gynecology. The Journal of Minimally Invasive Gynecology, 6(20), p.S182.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., CLINIQUE-GYNÉCOLOGIE, C.D.P., Leyland, N., Wolfman, W. and Allaire, C., 2013. Chirurgie esthétique génitale chez la femme. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1113-1114.
Singh, S.S., Mehra, N., Hopkins, L., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Liste de contrôle de la sécurité chirurgicale en obstétrique-gynécologie. Journal of Obstetrics and Gynaecology Canada, 35(1), pp.84-85.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., Leyland, N., Wolfman, W., Allaire, C. and Awadalla, A., 2013. Female genital cosmetic surgery. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1108-1112.
Murji, A., Glass, K. and Leyland, N., 2013. Isthmocele. Journal of Obstetrics and Gynaecology Canada, 35(9), p.780.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Abnormal uterine bleeding in pre-menopausal women. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.47
Wessels, J.M., Leyland, N. and Foster, W.G., 2012. Uterine Expression of Brain-Derived Neurotrophic Factor (BDNF) and Its Receptor During the Estrous Cycle and Menstrual Cycle. Biology of Reproduction, 87(Suppl 1), pp.335-335.
Lokuge, S., Fruci, V., Abraham, T., Youash, S., Bates, S. and Leyland, N., 2012. Does Innate Motor Skill Predict Medical Student’s Interest in Pursuing a Surgical Specialty?. Journal of Minimally Invasive Gynecology, 19(6), p.S25.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2011. Oral contraceptives and the risk of venous thromboembolism: an update. International Journal of Gynecology & Obstetrics, 112(3), pp.252-256.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Asymptomatic endometrial thickening. Journal of Obstetrics and Gynaecology Canada, 32(10), pp.990-999.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Adhesion prevention in gynaecological surgery. International Journal of Gynecology & Obstetrics, 111(2), pp193-7.
Leyland, N., Casper, R., Laberge, P., Singh, S.S., Allen, L., Arendas, K., Allaire, C., Awadalla, A., Best, C., Contestabile, E. and Dunn, S., 2010. Endometriosis: diagnosis and management. Journal of Obstetrics and Gynaecology Canada, 32(7), pp.S1-S3.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Épaississement endométrial asymptomatique. Journal of Obstetrics and Gynaecology Canada, 32(11), pp.1070-1081.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Hystérectomie supracervicale. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.69-76.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Prévention des adhérences en chirurgie gynécologique. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.603-608.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Supracervical hysterectomy. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.62-68.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2010. Oral contraceptives and the risk of venous thromboembolism: an update. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1192-1197.
Nicholas Leyland
BASc, MD, MHCM, FRCSC
Professor
General, Minimally Invasive Gynaecological Surgery
BIO
Dr. Nicholas Leyland earned his bachelor of applied science from the University of Guelph in 1979, and his medical degree from the University of Toronto in 1983. In 1988, he earned his FRCSC. In 2006, he graduated Summa Cum Lauda from Harvard University with a master’s of health care management. Dr. Leyland joined the Faculty of Health Sciences at McMaster University as an associate clinical professor in obstetrics and gynecology in 2009. On July 1, 2010, Dr. Leyland became professor and chair of the Department of Obstetrics & Gynecology.
RESEARCH
Research Themes
Endometriosis; Pelvic pain; Biomarkers; Abnormal uterine bleeding; Clinical practice guidelines; Minimally invasive surgery; Uterine fibroids; Selective progesterone receptor modulators; Perioperative surgical pain optimization; Simulation in surgical training
PUBLICATIONS
Taylor, H. S., Giudice, L. C., Lessey, B. A., Abrao, M. S., Kotarski, J., Archer, D. F.,… & Gallagher, J. C. (2017). Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. The New England journal of medicine. 377(1), p.28-40.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Mosher, A., Tsoulis, M., Leyland, N. and Foster, W., 2017.The Role of Melatonin and Prostaglandins in Endometriosis. Journal of Obstetrics and Gynaecology Canada, 39(5), p.398.
Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. (2017). Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. Journal of Obstetrics and Gynaecology Canada.
Arendas, K., Singh, S.S., Jackie, T., Clancy, A. and Leyland, N., 2017. Laparoscopic Cerclage: Challenging Cases. Journal of Obstetrics and Gynaecology Canada, 39(5), p.382.
Laberge, P., Garza-Leal, J., Fortin, C., Grainger, D., Johns, D.A., Adkins, R.T., Presthus, J., Basinski, C., Swarup, M., Gimpelson, R. and Leyland, N., 2017. A Randomized Controlled Multicenter US Food and Drug Administration Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System: One-Year Follow-Up Results. Journal of minimally invasive gynecology, 24(1), pp.124-132.
Leung, S., Leyland, N. and Murji, A., 2016. Decreasing Diagnostic Hysteroscopy Performed in the Operating Room: A Quality Improvement Initiative. Journal of Obstetrics and Gynaecology Canada, 38(4), pp.351-356.
Arendas, K. and Leyland, N.A., 2016. Use of ulipristal acetate for the management of fibroid-related acute abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 38(1), pp.80-83.
Murji, A., De Gasperis-Brigante, C. and Leyland, N., 2016. Richter’s Hernia After Laparoscopic Surgery. Journal of Minimally Invasive Gynecology, 24(4), pp.518-19.
Vilos, G.A., Allaire, C., Laberge, P.Y. and Leyland, N., 2016. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S550-S576.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N., Solnik, J. and Murji, A., 2016. Does Ulipristal Acetate Objectively Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology, 23(7), pp.S2-S3.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Dore, S., Marrin, M., DeSantis, J., Sabatino, L., DeFrance, B., Leyland, N., Gardosi, J. and Hutton, E., 2016. Implementation of an interprofessional team review of adverse events in obstetrics using a standardized computer tool: A mixed methods study. Journal of Obstetrics and Gynaecology Canada, 38(2), pp.168-176.
Laberge, P.Y., Garza-Leal, J., Fortin, C., Thiel, J., Johns, D.A., Grainger, D., Presthus, J., Adkins, T., Leyland, N., Basinski, C. and Gimpelson, R., 2016. A Randomized, Controlled, Multi-Center Trial of the Safety and Efficacy of the Minerva Endometrial Ablation System. One-Year Follow-Up Results. Journal of Minimally Invasive Gynecology, 23(7), p.S44.
Wessels, J.M., Kay, V.R., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2016. Assessing brain-derived neurotrophic factor as a novel clinical marker of endometriosis. Fertility and Sterility, 105(1), pp.119-128.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P. and Vilos, G., 2016. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S609-S628.
Singh, S., Best, C., Dunn, S., Leyland, N. and Wolfman, W.L., 2016. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S231-S263.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. Prise en charge des léiomyomes utérins. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.179-181.
Leyland, N., 2015. Myomectomy After Uliprisal Acetate. Journal of Minimally Invasive Gynecology, 22(6), p.S144.
Singh, S.S., Scott, S., Bougie, O. and Leyland, N., 2016. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 38(12), pp.S537-S549.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Mise à jour technique sur le morcellement tissulaire dans le cadre d’une chirurgie gynécologique: Son utilisation, ses complications et les risques liés à la présence insoupçonnée de tumeurs malignes. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.79-81.
Arendas, K., Aldossary, M., Cipolla, A., Leader, A. and Leyland, N.A., 2015. Hysteroscopic resection in the management of early-stage endometrial cancer: report of 2 cases and review of the literature. Journal of minimally invasive gynecology, 22(1), pp.34-39.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Endometrial ablation in the management of abnormal uterine bleeding. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.362-376.
Laberge, P., Leyland, N., Murji, A., Fortin, C., Martyn, P., Vilos, G., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S. and Heywood, M., 2015. Ablation de l’endomètre dans la prise en charge des saignements utérins anormaux. Journal of Obstetrics and Gynaecology Canada, 37(4), pp.377-379.
Murray-Davis, B., McDonald, H., Cross-Sudworth, F., Ahmed, R., Simioni, J., Dore, S., Marrin, M., DeSantis, J., Leyland, N., Gardosi, J. and Hutton, E., 2015. Learning from Adverse Events in Obstetrics: Is a Standardized Computer Tool an Effective Strategy for Root Cause Analysis?. Journal of Obstetrics and Gynaecology Canada, 37(8), pp.728-735.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2015. Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors. Human Reproduction, p.dev018.
Arendas, K., Foster, W.G. and Leyland, N.A., 2015. Impact of surgical excision of deep infltratng bowel endometriosis on health-related quality of life: review of current literature. Journal of Endometriosis and Pelvic Pain Disorders, 7(1), pp.3-9.
Singh, S.S., Scott, S., Bougie, O., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Bullen, A., Burnett, M., Goldstein, S. and Lemyre, M., 2015. Technical update on tissue morcellation during gynaecologic surgery: its uses, complications, and risks of unsuspected malignancy. Journal of Obstetrics and Gynaecology Canada, 37(1), pp.68-78.
Arendas, K., Coll-Black, M. and Leyland, N.A., 2015. Approach to the Obliterated Posterior Cul-De-Sac. Journal of Minimally Invasive Gynecology, 22(6), p.S120.
Leyland, N.A., 2015. The Selective Progesterone Receptor Modulator, Ulipristal Acetate, in the Management of Symptomatic Uterine Fibroids. Journal of minimally invasive gynecology, 22(6S), p.S73.
Bougie, O., Murji, A., Arendas, K., Vilos, G., Allaire, C., Laberge, P., Leyland, N., Chen, I. and Singh, S.S., 2015. Power Morcellation in Gynecologic Surgery: A Survey of Canadian Practice. Journal of Minimally Invasive Gynecology, 22(6), p.S99.
Vilos, G.A., Allaire, C., Laberge, P.Y., Leyland, N., Vilos, A.G., Murji, A. and Chen, I., 2015. The management of uterine leiomyomas. Journal of Obstetrics and Gynaecology Canada, 37(2), pp.157-178.
Arendas, K. and Leyland, N.A., 2014. Para-Ovarian Endomerioma in a Patient with a Congenital Uterine Anomaly. Journal of Minimally Invasive Gynecology, 21(6), p.S216.
Wessels, J.M., Wu, L., Leyland, N.A., Wang, H. and Foster, W.G., 2014. The brain-uterus connection: brain derived neurotrophic factor (BDNF) and its receptor (Ntrk2) are conserved in the mammalian uterus. PloS one, 9(4), p.e94036.
Wessels, J.M., Leyland, N.A., Agarwal, S.K. and Foster, W.G., 2014. Good proteins gone bad: brain-derived neurotrophic factor and its receptors in endometriotic implants and the role of estrogen. Fertility and Sterility, 102(3), pp.e10-e11.
Arendas, K., Al-Dossary, M.I., Leader, A. and Leyland, N.A., 2014. Successful Pregnancy after Targeted Hysteroscopy for Endometrial Adenocarcinoma. Journal of Minimally Invasive Gynecology, 21(6), p.S7.
Thiel, J.A., Rattray, D.D. and Leyland, N., 2014. Laparoscopic Radiofrequency Volumetric Thermal Ablation (RFVTA) of Symptomatic Fibroids and Myomectomy: A Randomized Trial of Uterine-Sparing Techniques in Canada. Journal of Minimally Invasive Gynecology, 21(6), p.S101.
Clancy, A. A., N. Leyland, and S. S. Singh. “Approach to Laparoscopic Cerclage.” Journal of Minimally Invasive Gynecology 21, no. 6 (2014): S65.
Tepperman, E.D., Sobel, M.L., Murji, A. and Leyland, N.A., 2014. Appendectomy in Gynecology. Journal of Minimally Invasive Gynecology, 21(6), p.S20.
Toor, K., Wessels, J.M., Agarwal, S.K., Leyland, N. and Foster, W.G., 2014. Clinical markers of endometriosis: have we been too quick to judge?. Medical hypotheses, 82(4), pp.493-501.
Laberge, P., Garza-Leal, J., Fortin, C., Basinski, C., Thiel, J., Leyland, N., Presthus, J., Johns, A., Grainger, D., Adkins, T. and Swarup, M., 2014. A Prospective, Randomized, Multi-Center, Controlled, International Clinical Study of the Safety and Efficacy of the MINERVA Endometrial Ablation System. 6 & 12-Months Follow-Up Results. Journal of Minimally Invasive Gynecology, 21(6), p.S144.
Arendas, K. and Leyland, N.A., 2014. Ulipristal Acetate for the Management of Acute Fibroid-Related Menorrhagia. Journal of Minimally Invasive Gynecology, 21(6), p.S196.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., CLINIQUE-GYNECOLOGIE, C.D.P., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M. and Lemyre, M., 2013. Saignements utérins anormaux chez les femmes préménopausées. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.476-479.
Wessels, J.M., Leyland, N.A., Agarwal, S., Murji, A. and Foster, W.G., 2013. Can brain-derived neurotrophic factor be a clinical marker for endometriosis?. Fertility and Sterility, 100(3), pp.S101-S102.
Murji, A., Sobel, M. and Leyland, N., 2013. Uterine and Internal Iliac Artery Ligation: Anatomy and Clinical Applications for Benign Gynecology. The Journal of Minimally Invasive Gynecology, 6(20), p.S182.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., CLINIQUE-GYNÉCOLOGIE, C.D.P., Leyland, N., Wolfman, W. and Allaire, C., 2013. Chirurgie esthétique génitale chez la femme. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1113-1114.
Singh, S.S., Mehra, N., Hopkins, L., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Dunn, S., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Liste de contrôle de la sécurité chirurgicale en obstétrique-gynécologie. Journal of Obstetrics and Gynaecology Canada, 35(1), pp.84-85.
Shaw, D., Lefebvre, G., Bouchard, C., Shapiro, J., Blake, J., Allen, L., Cassell, K., Leyland, N., Wolfman, W., Allaire, C. and Awadalla, A., 2013. Female genital cosmetic surgery. Journal of Obstetrics and Gynaecology Canada, 35(12), pp.1108-1112.
Murji, A., Glass, K. and Leyland, N., 2013. Isthmocele. Journal of Obstetrics and Gynaecology Canada, 35(9), p.780.
Singh, S., Best, C., Dunn, S., Leyland, N., Wolfman, W.L., Wolfman, W., Allaire, C., Awadalla, A., Heywood, M., Lemyre, M. and Marcoux, V., 2013. Abnormal uterine bleeding in pre-menopausal women. Journal of Obstetrics and Gynaecology Canada, 35(5), pp.47
Wessels, J.M., Leyland, N. and Foster, W.G., 2012. Uterine Expression of Brain-Derived Neurotrophic Factor (BDNF) and Its Receptor During the Estrous Cycle and Menstrual Cycle. Biology of Reproduction, 87(Suppl 1), pp.335-335.
Lokuge, S., Fruci, V., Abraham, T., Youash, S., Bates, S. and Leyland, N., 2012. Does Innate Motor Skill Predict Medical Student’s Interest in Pursuing a Surgical Specialty?. Journal of Minimally Invasive Gynecology, 19(6), p.S25.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2011. Oral contraceptives and the risk of venous thromboembolism: an update. International Journal of Gynecology & Obstetrics, 112(3), pp.252-256.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Asymptomatic endometrial thickening. Journal of Obstetrics and Gynaecology Canada, 32(10), pp.990-999.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Adhesion prevention in gynaecological surgery. International Journal of Gynecology & Obstetrics, 111(2), pp193-7.
Leyland, N., Casper, R., Laberge, P., Singh, S.S., Allen, L., Arendas, K., Allaire, C., Awadalla, A., Best, C., Contestabile, E. and Dunn, S., 2010. Endometriosis: diagnosis and management. Journal of Obstetrics and Gynaecology Canada, 32(7), pp.S1-S3.
Wolfman, W., Leyland, N., Heywood, M., Singh, S.S., Rittenberg, D.A., Soucy, R., Allaire, C., Awadalla, A., Best, C., Dunn, S. and Leroux, N., 2010. Épaississement endométrial asymptomatique. Journal of Obstetrics and Gynaecology Canada, 32(11), pp.1070-1081.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Hystérectomie supracervicale. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.69-76.
Robertson, D., Lefebvre, G., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Contestabile, E., Dunn, S., Heywood, M. and Leroux, N., 2010. Prévention des adhérences en chirurgie gynécologique. Journal of Obstetrics and Gynaecology Canada, 32(6), pp.603-608.
Kives, S., Lefebvre, G., Wolfman, W., Leyland, N., Allaire, C., Awadalla, A., Best, C., Leroux, N., Potestio, F., Rittenberg, D. and Soucy, R., 2010. Supracervical hysterectomy. Journal of Obstetrics and Gynaecology Canada, 32(1), pp.62-68.
Reid, R., Leyland, N., Wolfman, W., Allaire, C., Awadalla, A., Best, C., Dunn, S., Lemyre, M., Marcoux, V., Menard, C. and Potestio, F., 2010. Oral contraceptives and the risk of venous thromboembolism: an update. Journal of Obstetrics and Gynaecology Canada, 32(12), pp.1192-1197.
Mathew Leonardi
Assistant Professor
Minimally Invasive Gynaecological Surgery
Mathew Leonardi
Assistant Professor
Minimally Invasive Gynaecological Surgery
Lea Luketic
MSc, MD, FRCSC
Assistant Professor
General
BIO
Dr. Lea Luketic is currently an assistant professor of obstetrics and gynecology at McMaster University and a practicing obstetrician and gynecologist at St. Joseph’s Healthcare. She earned her bachelor of science at the University of Guelph and a master of science at McMaster University. She obtained her MD from the University of Toronto in 2010. Her residency training in obstetrics and gynecology was completed at McMaster University in 2015. She then went on to complete a fellowship in minimally invasive gynecologic surgery at Mount Sinai Hospital at the University of Toronto and joined the Department of Obstetrics & Gynecology at McMaster University in 2017. She is currently working on finishing a master of science in healthcare quality at Queen’s University.
Awards
Resident Teaching Award in 2015
RESEARCH INTERESTS
Research Themes
Uterine fibroids; Patient safety; Healthcare quality; Minimally invasive gynecologic surgery
PUBLICATIONS
Luketic, L., Jacobson, M., Allen, L., Bernardini, M. and Sobel, M., 2017. Risk-Reducing Salpingo-Oophorectomy in BRCA Mutation Carriers. Journal of Obstetrics and Gynaecology Canada, 39(5), p.397.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Zwayne, N., Kives, S., Luketic, L. and Allen, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Pediatric and Adolescent Gynecology, 29(2), p.165
Zwayne, N., Allen, L., Kives, S. and Luketic, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Obstetrics and Gynaecology Canada, 38(5), p.504.
Luketic, L., Sobel, M. and Murji, A., 2016. Surgical Management of Cesarean Scar Pregnancy. Journal of Minimally Invasive Gynecology, 23(7), p.S154.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World Without Indigo Carmine. Journal of Obstetrics and Gynaecology Canada, 38(5), p.493.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World without Indigo Carmine. Journal of Minimally Invasive Gynecology, 23(7), p.S157.
Luketic, L. and Murji, A., 2016. Options to Evaluate Ureter Patency at Cystoscopy in a World Without Indigo Carmine. Journal of minimally invasive gynecology, 23(6), pp.878-885.
White-Campbell, M., Luketic, L. and MacDonald, S., 2014. Psychosocial groupwork for older adults having substance use and mental health issues. Groupwork, 24(1), pp.60-80.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Luketic, L., Delanghe, J., Sobol, P.T., Yang, P., Frotten, E., Mossman, K.L., Gauldie, J., Bramson, J. and Wan, Y., 2007. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. The Journal of Immunology, 179(8), pp.5024-5032.
Lea Luketic
MSc, MD, FRCSC
Assistant Professor
General
BIO
Dr. Lea Luketic is currently an assistant professor of obstetrics and gynecology at McMaster University and a practicing obstetrician and gynecologist at St. Joseph’s Healthcare. She earned her bachelor of science at the University of Guelph and a master of science at McMaster University. She obtained her MD from the University of Toronto in 2010. Her residency training in obstetrics and gynecology was completed at McMaster University in 2015. She then went on to complete a fellowship in minimally invasive gynecologic surgery at Mount Sinai Hospital at the University of Toronto and joined the Department of Obstetrics & Gynecology at McMaster University in 2017. She is currently working on finishing a master of science in healthcare quality at Queen’s University.
Awards
Resident Teaching Award in 2015
RESEARCH INTERESTS
Research Themes
Uterine fibroids; Patient safety; Healthcare quality; Minimally invasive gynecologic surgery
PUBLICATIONS
Luketic, L., Jacobson, M., Allen, L., Bernardini, M. and Sobel, M., 2017. Risk-Reducing Salpingo-Oophorectomy in BRCA Mutation Carriers. Journal of Obstetrics and Gynaecology Canada, 39(5), p.397.
Luketic, L., Shirreff, L., Kives, S., Liu, G., El Sugy, R., Leyland, N.,… & Murji, A. (2017). Does Ulipristal Acetate Affect Surgical Experience at Laparoscopic Myomectomy?. Journal of Minimally Invasive Gynecology. 24(5), p.797-802
Zwayne, N., Kives, S., Luketic, L. and Allen, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Pediatric and Adolescent Gynecology, 29(2), p.165
Zwayne, N., Allen, L., Kives, S. and Luketic, L., 2016. A Modified Version of the Laparoscopic Assisted Davydov Procedure. Journal of Obstetrics and Gynaecology Canada, 38(5), p.504.
Luketic, L., Sobel, M. and Murji, A., 2016. Surgical Management of Cesarean Scar Pregnancy. Journal of Minimally Invasive Gynecology, 23(7), p.S154.
Murji, A., Luketic, L., Sobel, M.L., Kulasegaram, K.M., Leyland, N. and Posner, G., 2016. Evaluating the effect of distractions in the operating room on clinical decision-making and patient safety. Surgical endoscopy, 30(10), pp.4499-4504.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World Without Indigo Carmine. Journal of Obstetrics and Gynaecology Canada, 38(5), p.493.
Luketic, L. and Murji, A., 2016. Cystoscopy in a World without Indigo Carmine. Journal of Minimally Invasive Gynecology, 23(7), p.S157.
Luketic, L. and Murji, A., 2016. Options to Evaluate Ureter Patency at Cystoscopy in a World Without Indigo Carmine. Journal of minimally invasive gynecology, 23(6), pp.878-885.
White-Campbell, M., Luketic, L. and MacDonald, S., 2014. Psychosocial groupwork for older adults having substance use and mental health issues. Groupwork, 24(1), pp.60-80.
Murji, A., Luketic, L., Kulasegaram, M., Leyland, N. and Grierson, L., 2013. Evaluating the Effect of Distractions on Residents in the Operating Room. Journal of Minimally Invasive Gynecology, 20(6), p.S24.
Luketic, L., Delanghe, J., Sobol, P.T., Yang, P., Frotten, E., Mossman, K.L., Gauldie, J., Bramson, J. and Wan, Y., 2007. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. The Journal of Immunology, 179(8), pp.5024-5032.
Meghan O'Leary
Assistant Professor
Minimally Invasive Gynaecological Surgery
BIO
Dr. Meghan O’Leary (she/her) is a Minimally Invasive Gynecologic Surgeon working at St. Joseph’s Healthcare in Hamilton, Ontario affiliated with McMaster University. She completed her residency in OBGYN at McMaster University and followed this with a 2-year MIGS fellowship in Calgary, Alberta. The focus of her fellowship training was endometriosis/adenomyosis management with a focus on excisional surgery, in addition to management of fibroids, and other advanced hysteroscopic and laparoscopic operations. Her clinical passions and research interests include medical and surgical education and triaging systems for increasing access to endometriosis specialists. She is an East Coaster at heart, enjoying trips to her hometown of St. John’s, Newfoundland
Meghan O'Leary
Assistant Professor
Minimally Invasive Gynaecological Surgery
BIO
Dr. Meghan O’Leary (she/her) is a Minimally Invasive Gynecologic Surgeon working at St. Joseph’s Healthcare in Hamilton, Ontario affiliated with McMaster University. She completed her residency in OBGYN at McMaster University and followed this with a 2-year MIGS fellowship in Calgary, Alberta. The focus of her fellowship training was endometriosis/adenomyosis management with a focus on excisional surgery, in addition to management of fibroids, and other advanced hysteroscopic and laparoscopic operations. Her clinical passions and research interests include medical and surgical education and triaging systems for increasing access to endometriosis specialists. She is an East Coaster at heart, enjoying trips to her hometown of St. John’s, Newfoundland
Sarah Scattolon
MD, FRCSC
Assistant Professor
General; Minimally Invasive Gynecological Surgery
BIO
Dr. Sarah Scattolon is an academic obstetrician and minimally invasive gynecologic surgeon in the Department of Obstetrics & Gynecology at McMaster University. Dr. Scattolon completed her doctorate of medicine at the University of Toronto and her obstetrics and gynecology residency at McMaster University. She has also completed a two-year fellowship in minimally invasive gynecology surgery at McMaster University.
Dr. Scattolon’s practice focuses on complex gynecologic surgery, endometriosis care, fibroids and low-risk obstetrics. She plays an active role in teaching trainees of all levels and is currently pursuing a master’s in health research methodology with a focus on health services. Dr. Scattolon’s research interests include optimization of medical and surgical treatments of endometriosis, knowledge translation and adherence to clinical practice guidelines.
RESEARCH INTERESTS
Endometriosis; Pelvic pain; Knowledge translation; Clinical practice guidelines; Medical therapies for Endometriosis
Sarah Scattolon
MD, FRCSC
Assistant Professor
General; Minimally Invasive Gynecological Surgery
BIO
Dr. Sarah Scattolon is an academic obstetrician and minimally invasive gynecologic surgeon in the Department of Obstetrics & Gynecology at McMaster University. Dr. Scattolon completed her doctorate of medicine at the University of Toronto and her obstetrics and gynecology residency at McMaster University. She has also completed a two-year fellowship in minimally invasive gynecology surgery at McMaster University.
Dr. Scattolon’s practice focuses on complex gynecologic surgery, endometriosis care, fibroids and low-risk obstetrics. She plays an active role in teaching trainees of all levels and is currently pursuing a master’s in health research methodology with a focus on health services. Dr. Scattolon’s research interests include optimization of medical and surgical treatments of endometriosis, knowledge translation and adherence to clinical practice guidelines.
RESEARCH INTERESTS
Endometriosis; Pelvic pain; Knowledge translation; Clinical practice guidelines; Medical therapies for Endometriosis